Microglial reactivity and functional deficits following traumatic brain injury in the neonate rat

2021 ◽  
Author(s):  
Lauren A. Hanlon
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Functional Deficits ◽  
Neonate Rat

scholarly journals Poly-arginine Peptide R18D Reduces Neuroinflammation and Functional Deficits Following Traumatic Brain Injury in the Long-Evans Rat

2019 ◽  
Vol 25 (4) ◽  
pp. 1563-1572 ◽  
Author(s):  
Li Shan Chiu ◽  
Ryan S. Anderton ◽  
Jane L. Cross ◽  
Vince W. Clark ◽  
Neville W. Knuckey ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Functional Deficits ◽  
Long Evans

The Neurosteroids Progesterone and Allopregnanolone Reduce Cell Death, Gliosis, and Functional Deficits after Traumatic Brain Injury in Rats

2005 ◽  
Vol 22 (1) ◽  
pp. 106-118 ◽  
Author(s):  
Myriam Djebaili ◽  
Qingmin Guo ◽  
Edward H. Pettus ◽  
Stuart W. Hoffman ◽  
Donald G. Stein
Keyword(s):  
Traumatic Brain Injury ◽  
Cell Death ◽  
Brain Injury ◽  
Functional Deficits

scholarly journals Predicting longitudinal patterns of functional deficits in children with traumatic brain injury.

2009 ◽  
Vol 23 (3) ◽  
pp. 271-282 ◽  
Author(s):  
Taryn B. Fay ◽  
Keith Owen Yeates ◽  
Shari L. Wade ◽  
Dennis Drotar ◽  
Terry Stancin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Longitudinal Patterns ◽  
Functional Deficits

Neurostimulation for traumatic brain injury

2014 ◽  
Vol 121 (5) ◽  
pp. 1219-1231 ◽  
Author(s):  
Samuel S. Shin ◽  
C. Edward Dixon ◽  
David O. Okonkwo ◽  
R. Mark Richardson
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Animal Models ◽  
Cognitive Deficits ◽  
Public Health Problem ◽  
Functional Deficits ◽  
Therapeutic Modalities ◽  
Significant Public Health Problem ◽  
Significant Public Health ◽  
Deep Brain

Traumatic brain injury (TBI) remains a significant public health problem and is a leading cause of death and disability in many countries. Durable treatments for neurological function deficits following TBI have been elusive, as there are currently no FDA-approved therapeutic modalities for mitigating the consequences of TBI. Neurostimulation strategies using various forms of electrical stimulation have recently been applied to treat functional deficits in animal models and clinical stroke trials. The results from these studies suggest that neurostimulation may augment improvements in both motor and cognitive deficits after brain injury. Several studies have taken this approach in animal models of TBI, showing both behavioral enhancement and biological evidence of recovery. There have been only a few studies using deep brain stimulation (DBS) in human TBI patients, and future studies are warranted to validate the feasibility of this technique in the clinical treatment of TBI. In this review, the authors summarize insights from studies employing neurostimulation techniques in the setting of brain injury. Moreover, they relate these findings to the future prospect of using DBS to ameliorate motor and cognitive deficits following TBI.

Magnesium attenuates persistent functional deficits following diffuse traumatic brain injury in rats

2003 ◽  
Vol 336 (1) ◽  
pp. 41-44 ◽  
Author(s):  
Robert Vink ◽  
Christine A. O'Connor ◽  
Alan J. Nimmo ◽  
Deanne L. Heath
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Functional Deficits

Neurogenic inflammation is associated with development of edema and functional deficits following traumatic brain injury in rats

Neuropeptides ◽  
2004 ◽  
Vol 38 (1) ◽  
pp. 40-47 ◽  
Author(s):  
A.J. Nimmo ◽  
I. Cernak ◽  
D.L. Heath ◽  
X. Hu ◽  
C.J. Bennett ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Neurogenic Inflammation ◽  
Functional Deficits

Motor and Cognitive Functional Deficits Following Diffuse Traumatic Brain Injury in the Immature Rat

1997 ◽  
Vol 14 (2) ◽  
pp. 99-108 ◽  
Author(s):  
P. DAVID ADELSON ◽  
C. EDWARD DIXON ◽  
PAUL ROBICHAUD ◽  
PATRICK M. KOCHANEK
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Immature Rat ◽  
Functional Deficits
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