Effect of thermal treatment on generation of reactive oxidative species (ROS) from sugar solutions

2021 ◽  
Author(s):  
Qingyang (Carly) Wang
2016 ◽  
Vol 196 ◽  
pp. 301-308 ◽  
Author(s):  
Qingyang Wang ◽  
Erwann Durand ◽  
Ryan J. Elias ◽  
Rohan V. Tikekar

2022 ◽  
Vol 19 (2) ◽  
pp. 025601
Author(s):  
Alessandra R Lima ◽  
Lucas D Dias ◽  
Matheus Garbuio ◽  
Natalia M Inada ◽  
Vanderlei S Bagnato

Abstract The control of pests and vector-borne diseases (VDBs) are considered public health issues Worldwide. Among the control techniques and pesticides used so far, photodynamic inactivation (PDI) has been shown as an eco-friendly, low cost, and efficient approach to eliminate pests and VDBs. PDI is characterized using a photosensitizing molecule, light and molecular oxygen (O2) resulting in production of reactive oxidative species which can promote the oxidation of biomolecules on pests and vectors. Herein, we review the past 51 years (1970–2021) regarding the use of photo pesticides, reporting the most important parameters for the protocol applied, the results obtained, and limitations. Moreover, we described the mechanism of action of the PDI, main classes of photopesticides used so far as well as the cell death mechanism resulting from the photodynamic action.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Yi Song ◽  
Zhiqi Zhang ◽  
Hang Xing ◽  
Yixin He ◽  
guangbin shi ◽  
...  

Introduction: Cardioplegic-ischemia/reperfusion (CP-I/R) and diabetes mellitus (DM) are correlated with coronary endothelial dysfunction and inactivated small conductance calcium-activated-potassium (SK) channels. Increased reactive oxidative species (ROS), such as mitochondrial ROS (mROS) may contribute to oxidative injury. Thus, we hypothesized that inhibition of mROS may protect coronary SK channels and endothelial function against CP-I/R-induced injury. Objective: A cardioplegic hypoxia and reoxygenation (CP-H/R) model consisting of coronary endothelial cells and small coronary arteries with or without DM were employed for examining whether MT could protect against coronary endothelial and SK channel dysfunction. Methods: Small coronary arteries (<150μm) and endothelial cells (MHECs) were dissected from the mouse heart with non-diabetes (ND) and DM (n=6/group). The microvessels or MHECs were subjected to hypoxia with cardioplegia and re-oxygenated. The microvessels or MHECs were treated with or without MT (10 -5 M) 5-minutes before and during CP-hypoxia. Microvascular vasodilation function was assessed in vitro by administration of vasoconstrictor, then ADP or NS309,respectively. K + currents of MHECs were measured by whole-cell patch clamp. The levels of endothelial mROS was measured by MitoSox TM . Results: CP-H/R significantly attenuated endothelial SK channels activity and the coronary relaxation responses to ADP and NS309 in the ND and DM groups. Treatment with MT enhanced coronary relaxation responses to ADP or NS309 ( p <0.05, Fig 1. A, B), and similar findings were seen in endothelial SK channel currents in both ND and DM MHECs ( p <0.05, Fig 1. C-F). In addition, treating MHECs with MT reduced CP-H/R-induced mROS in ND and DM groups. Conclusions: Administration of MT improves endothelial SK channels activity which may contribute to its enhancement of endothelium-dependent vasorelaxation following CP-H/R.


2019 ◽  
Vol 137 ◽  
pp. 74-86 ◽  
Author(s):  
Xiaoyu Zhang ◽  
Qin Xia ◽  
Rui Wei ◽  
Hongfei Song ◽  
Jiaqi Mi ◽  
...  

2020 ◽  
Vol 396 ◽  
pp. 122616 ◽  
Author(s):  
Xavier Bellanger ◽  
Raphaël Schneider ◽  
Clément Dezanet ◽  
Boussad Arroua ◽  
Lavinia Balan ◽  
...  

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