Development and fabrication of silver composite PEEK to prevent microbial attachment and periprosthetic infection

2021 ◽  
Author(s):  
David Joseph Jaekel
Keyword(s):  
Periprosthetic Infection ◽  
Silver Composite ◽  
Microbial Attachment

Application of Innovative Hydroxyapatite Materials in 3D Printing for Biocompatible Voice Implants

2018 ◽  
Vol 69 (4) ◽  
pp. 840-842
Author(s):  
Wojciech Musialik ◽  
Marcin Nabialek ◽  
Slawomir Letkiewicz ◽  
Andrei Victor Sandu ◽  
Katarzyna Bloch
Keyword(s):  
3D Printing ◽  
Surgical Procedures ◽  
Bacterial Infections ◽  
Fungal Infections ◽  
Colloidal Silver ◽  
Bone Implants ◽  
External Ring ◽  
Voice Prostheses ◽  
3D Printers ◽  
Silver Composite

The paper presents the possibility of using an innovative hydroxyapatite filament Ca10(PO4)6(OH)2 for printing in 3D printers of bone implants and the possibility of using it during implantation with voice prostheses. The introduction of an additional colloidal silver composite in voice implants will contribute to the reduction of bacterial infections, fungal infections and granulomatous hyperplasia. The creation of a stable external ring of the vocal fistula will remove complications associated with it with enlargement of the fistula and leakiness of voice implants. The ability to print with a hydroxyapatite filament will allow digital pre-surgery modeling of bone implants suited to the needs of surgical procedures.

scholarly journals Superhydrophobic Nanocoatings as Intervention against Biofilm-Associated Bacterial Infections

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1046
Author(s):  
Yinghan Chan ◽  
Xun Hui Wu ◽  
Buong Woei Chieng ◽  
Nor Azowa Ibrahim ◽  
Yoon Yee Then
Keyword(s):  
Biofilm Formation ◽  
Bacterial Infections ◽  
Therapeutic Strategies ◽  
Public Healthcare ◽  
Persistent Infections ◽  
Promising Strategy ◽  
Antimicrobial Interventions ◽  
Novel Therapeutic Strategies ◽  
Insight Into ◽  
Microbial Attachment

Biofilm formation represents a significant cause of concern as it has been associated with increased morbidity and mortality, thereby imposing a huge burden on public healthcare system throughout the world. As biofilms are usually resistant to various conventional antimicrobial interventions, they may result in severe and persistent infections, which necessitates the development of novel therapeutic strategies to combat biofilm-based infections. Physicochemical modification of the biomaterials utilized in medical devices to mitigate initial microbial attachment has been proposed as a promising strategy in combating polymicrobial infections, as the adhesion of microorganisms is typically the first step for the formation of biofilms. For instance, superhydrophobic surfaces have been shown to possess substantial anti-biofilm properties attributed to the presence of nanostructures. In this article, we provide an insight into the mechanisms underlying biofilm formation and their composition, as well as the applications of nanomaterials as superhydrophobic nanocoatings for the development of novel anti-biofilm therapies.

Cultures From Genitourinary Prostheses at Reoperation: Questioning the Role of Staphylococcus Epidermidis in Periprosthetic Infection

1995 ◽  
Vol 154 (2) ◽  
pp. 387-390 ◽  
Author(s):  
Mark R. Licht ◽  
Drogo K. Montague ◽  
Kenneth W. Angermeier ◽  
Milton M. Lakin
Keyword(s):  
Staphylococcus Epidermidis ◽  
Periprosthetic Infection

scholarly journals The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites

2015 ◽  
Vol 7 (269) ◽  
pp. 269ra1-269ra1 ◽  
Author(s):  
C. Schneider ◽  
D. F. Smith ◽  
R. D. Cummings ◽  
K. F. Boligan ◽  
R. G. Hamilton ◽  
...  
Keyword(s):  
Human Igg ◽  
Attachment Sites ◽  
Microbial Attachment

Antibacterial activities of centrifugally spun polyethylene oxide/silver composite nanofibers

2021 ◽  
Author(s):  
Md Toukir Hasan ◽  
Ramiro Gonzalez ◽  
Mircea Chipara ◽  
Luis Materon ◽  
Jason Parsons ◽  
...  
Keyword(s):  
Polyethylene Oxide ◽  
Composite Nanofibers ◽  
Antibacterial Activities ◽  
Silver Composite

scholarly journals OPTIMIZATION OF DIAGNOSIS AND TREATMENT FOR PERIPROSTHETIC KNEE INFECTION

2017 ◽  
pp. 14-19
Author(s):  
S. P. Shpinyak ◽  
A. P. Barabash ◽  
Yu. A. Barabash
Keyword(s):  
Public Health ◽  
Periprosthetic Infection ◽  
Public Health System ◽  
Diagnosis And Treatment ◽  
Surgical Interventions ◽  
Knee Infection ◽  
Long Period ◽  
Periprosthetic Knee Infection

Purpose of study: to analyze the modern approaches to classification of large joints periprosthetic infection (PPI) and evaluate the results of revision surgical interventions in patients with deep PPI of the knee. Patients and methods. One hundred fifty three patients, 51 men and 102 women (mean age 57.3±12.4 years), with deep PPI were operated on. Treatment tactics was determined by the term after primary operation. In early PPI (n=31) sanitation interventions with implant preservation and in late PPI (n=122) – two step interventions with long period between the operations (over 4 weeks) were performed. Results. Follow up made up from 2 to 5 years. Sanitation interventions with implant preservation were successful in71% of patients. In group of patients with late PPI satisfactory results were achieved in 89.6% of cases. On the basis of the obtained data the variants of diagnosis and treatment tactics optimization as well as its adaptation to domestic public health system were proposed.

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