MALD/I TOF PSD and CID: Understanding precision, resolution, and mass accuracy and MALD/I TOFMS: Investigation of discrimination issues related to solubility

2021 ◽  
Author(s):  
Andrew J. Hoteling
Keyword(s):  
Mass Accuracy

Unprecedented Ultrahigh Resolution FT-ICR Mass Spectrometry and Parts-Per-Billion Mass Accuracy Enable Direct Characterization of Nickel and Vanadyl Porphyrins in Petroleum from Natural Seeps

2014 ◽  
Vol 28 (4) ◽  
pp. 2454-2464 ◽  
Author(s):  
Amy M. McKenna ◽  
Jeffrey T. Williams ◽  
Jonathan C. Putman ◽  
Christoph Aeppli ◽  
Christopher M. Reddy ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mass Accuracy ◽  
Ultrahigh Resolution ◽  
Ft Icr

scholarly journals Co-formulants in plant protection products: An analytical approach to their determination by gas chromatography–high resolution mass accuracy spectrometry

Talanta ◽  
2021 ◽  
pp. 122641
Author(s):  
Antonio Jesús Maldonado-Reina ◽  
Rosalía López-Ruiz ◽  
Antonia Garrido-Frenich ◽  
F. Javier Arrebola ◽  
Roberto Romero-González
Keyword(s):  
Gas Chromatography ◽  
High Resolution ◽  
Analytical Approach ◽  
Plant Protection ◽  
Plant Protection Products ◽  
Mass Accuracy ◽  
High Resolution Mass ◽  
Resolution Mass

The proteomic future: where mass spectrometry should be taking us

2012 ◽  
Vol 444 (2) ◽  
pp. 169-181 ◽  
Author(s):  
Jay J. Thelen ◽  
Ján A. Miernyk
Keyword(s):  
Mass Spectrometry ◽  
Gel Electrophoresis ◽  
Protein Structures ◽  
Research Area ◽  
Mass Accuracy ◽  
Two Dimensional ◽  
Two Dimensional Gel Electrophoresis ◽  
Post Translational Modifications ◽  
Peptide Separation ◽  
Research Areas

A newcomer to the -omics era, proteomics, is a broad instrument-intensive research area that has advanced rapidly since its inception less than 20 years ago. Although the ‘wet-bench’ aspects of proteomics have undergone a renaissance with the improvement in protein and peptide separation techniques, including various improvements in two-dimensional gel electrophoresis and gel-free or off-gel protein focusing, it has been the seminal advances in MS that have led to the ascension of this field. Recent improvements in sensitivity, mass accuracy and fragmentation have led to achievements previously only dreamed of, including whole-proteome identification, and quantification and extensive mapping of specific PTMs (post-translational modifications). With such capabilities at present, one might conclude that proteomics has already reached its zenith; however, ‘capability’ indicates that the envisioned goals have not yet been achieved. In the present review we focus on what we perceive as the areas requiring more attention to achieve the improvements in workflow and instrumentation that will bridge the gap between capability and achievement for at least most proteomes and PTMs. Additionally, it is essential that we extend our ability to understand protein structures, interactions and localizations. Towards these ends, we briefly focus on selected methods and research areas where we anticipate the next wave of proteomic advances.

Number of Shoes Tested During a Running Shoe Mass Perception Task May Not Influence Accuracy

2020 ◽  
Vol 127 (1-4) ◽  
pp. 23-29
Author(s):  
James G. Saxton ◽  
Joel G. Greenya ◽  
Christopher L. Kliethermes ◽  
David S. Senchina
Keyword(s):  
Young Adult ◽  
Experimental Design ◽  
Rank Order ◽  
Mass Accuracy ◽  
Testing Session ◽  
Adult Males ◽  
Order Task ◽  
Running Shoes ◽  
Design Factors ◽  
Analogue Scales

Commercially available running shoes differ in terms of their relative masses. It is unclear how well consumers may be able to judge mass differences from wearing alone, though previous studies suggest that perceptual outcomes may be influenced by experimental design factors such as the length of time worn. The purpose of this study was to investigate how the number of shoes used in a testing session impacts wearers' mass perceptual accuracy. Forty-eight young adult males ran for 5 min in 4 pairs of shoes (their own running shoes plus 3 unfamiliar pairs) before being asked whether an unfamiliar running shoe was heavier or lighter than their own, and to indicate perceptions of shoe heaviness (mass), comfort, stability, and temperature using visual analogue scales (VAS). A subset (n=18) was also asked to provide global rank orderings after wearing all 4 pairs of shoes. Participants were 67% accurate in the heavier/lighter task and 64% accurate in the global rank order task. Global rank order scores and VAS heaviness marks were significantly and positively correlated. Mass accuracy scores (n=48) were then compared to a previous study (n=25) performed by the same investigators using the same methods but with 6 pairs of shoes instead of 4. No difference in accuracy scores for either the heavier/lighter comparisons or global rank order scores between the study populations was found, suggesting that the number of test shoes may not influence mass perception accuracy.

scholarly journals ProteinProcessor: A probabilistic analysis using mass accuracy and the MS spectrum

PROTEOMICS ◽  
2016 ◽  
Vol 16 (18) ◽  
pp. 2480-2490 ◽  
Author(s):  
Jonathan A. Epstein ◽  
Paul S. Blank ◽  
Brian C. Searle ◽  
Aaron D. Catlin ◽  
Stephanie M. Cologna ◽  
...  
Keyword(s):  
Probabilistic Analysis ◽  
Mass Accuracy

Mass Accuracy and Sequence Requirements for Protein Database Searching

1999 ◽  
Vol 275 (1) ◽  
pp. 39-46 ◽  
Author(s):  
M.Kirk Green ◽  
Murray V. Johnston ◽  
Barbara S. Larsen
Keyword(s):  
Mass Accuracy ◽  
Database Searching ◽  
Protein Database ◽  
Sequence Requirements
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