Mechanistic modeling and model-based studies in spontaneous solution polymerization of alkyl acrylate monomers

This thesis is concerned with the integration of a model-based and experimental analysis for the systematic investigation of transient electrodialysis (ED) processes. In this context a mechanistic process model for transient ED systems is developed which is based on a rigorous dynamic description of the underlying ionic transport processes. Important requirements for a systematic model development are elaborated in a systematic manner. This includes the development of a new method for the characterization of partial differential-algebraic equations and an experimental sensitivity analysis of a transient electrodialysis system. The findings can easily be generalized to related electrochemical processes such as fuel cells or batteries. By this means this work provides important results for scientist and engineers in the fields of mechanistic modeling, electromembrane processes and electrochemical systems. ...

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Long-Range Polar Effect on the C-ON Bond Homolysis in (tert-Butyl[1-(diethylphosphonyl)-2,2-dimethylpropyl]aminoxyl) SG1-Based Alkoxyamines

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc20042223 ◽

2004 ◽

Vol 69 (12) ◽

pp. 2223-2238 ◽

Cited By ~ 23

Author(s):

Denis Bertin ◽

Didier Gigmes ◽

Sylvain R. A. Marque ◽

Stephan Milardo ◽

Jérôme Peri ◽

...

Keyword(s):

Radical Polymerization ◽

Rate Constant ◽

Rate Constants ◽

Bond Cleavage ◽

Nitroxyl Radicals ◽

Cleavage Rate ◽

Factors Influencing ◽

Alkyl Acrylate ◽

Bond Homolysis ◽

Acrylate Monomers

Alkoxyamines and persistent nitroxyl radicals are important regulators of nitroxide-mediated radical polymerization. Because the polymerization times decrease with the increasing rate constant of the homolysis of the C-ON bond between the polymer chain and the nitroxyl moiety, the factors influencing the cleavage rate constant are of considerable interest. Because alkyl acrylate monomers are among the most used in polymerization, we present the measures of the rate constants (kd) of the C-ON bond cleavage for new SG1 based alkoxyamine models containing para-substituted aromatic acrylates (4-XC6H4OC(O)C(Me)H-SG1). It appears that the values of kd increase with the electron-withdrawing properties of the para-substituent groups (4-X) of the ester SG1-based alkoxyamines.

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Representation, abstraction, and simple-minded sophisticates

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002942 ◽

2020 ◽

Vol 43 ◽

Author(s):

Peter Dayan

Keyword(s):

Decision Theory ◽

Predictive Coding ◽

Bayesian Decision Theory ◽

Bayesian Decision ◽

Model Based ◽

Model Free

Abstract Bayesian decision theory provides a simple formal elucidation of some of the ways that representation and representational abstraction are involved with, and exploit, both prediction and its rather distant cousin, predictive coding. Both model-free and model-based methods are involved.

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Quantitative Model-Based Image Analysis of NuMa Distribution Links Nuclear Organization with Cell Phenotype

Microscopy and Microanalysis ◽

10.1017/s1431927600028968 ◽

2001 ◽

Vol 7 (S2) ◽

pp. 578-579

Author(s):

David W. Knowles ◽

Sophie A. Lelièvre ◽

Carlos Ortiz de Solόrzano ◽

Stephen J. Lockett ◽

Mina J. Bissell ◽

...

Keyword(s):

Image Analysis ◽

Mammary Epithelial Cells ◽

Nuclear Organization ◽

Critical Role ◽

Quantitative Model ◽

Mammary Epithelial ◽

Cell Phenotype ◽

Proliferating Cells ◽

Mitotic Apparatus ◽

Model Based

The extracellular matrix (ECM) plays a critical role in directing cell behaviour and morphogenesis by regulating gene expression and nuclear organization. Using non-malignant (S1) human mammary epithelial cells (HMECs), it was previously shown that ECM-induced morphogenesis is accompanied by the redistribution of nuclear mitotic apparatus (NuMA) protein from a diffuse pattern in proliferating cells, to a multi-focal pattern as HMECs growth arrested and completed morphogenesis . A process taking 10 to 14 days.To further investigate the link between NuMA distribution and the growth stage of HMECs, we have investigated the distribution of NuMA in non-malignant S1 cells and their malignant, T4, counter-part using a novel model-based image analysis technique. This technique, based on a multi-scale Gaussian blur analysis (Figure 1), quantifies the size of punctate features in an image. Cells were cultured in the presence and absence of a reconstituted basement membrane (rBM) and imaged in 3D using confocal microscopy, for fluorescently labeled monoclonal antibodies to NuMA (fαNuMA) and fluorescently labeled total DNA.

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Model-Based Clustering and Classification for Data Science

10.1017/9781108644181 ◽

2019 ◽

Cited By ~ 17

Author(s):

Charles Bouveyron ◽

Gilles Celeux ◽

T. Brendan Murphy ◽

Adrian E. Raftery

Keyword(s):

Data Science ◽

Model Based Clustering ◽

Model Based ◽

Clustering And Classification

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