Empirical Quantification of the Impact of Nonlinear Soil Behavior on Site Response

2016 ◽  
Vol 106 (4) ◽  
pp. 1710-1719 ◽  
Author(s):  
Julie Régnier ◽  
Héloïse Cadet ◽  
Pierre‐Yves Bard
2014 ◽  
Vol 926-930 ◽  
pp. 4205-4208
Author(s):  
Yan Li Wu ◽  
Qing Feng Zhang ◽  
Ran Zhuo Zhang ◽  
Xiao Ming Mao ◽  
Xin Hua Sun

In the past ten years, methane has a greenhouse gas, and its concentration increases by 1% per year, while an estimated worldwide annual landfill cover soil surface from escaping methane is about 20 to 70 Mtpa. Microbial methane oxidation can be carried out about 80% of global consumption of methane, the soil microbial methane oxidation can reduce methane escaping from the soil to the atmosphere. Both in domestic and foreign ash recycling in landfill cover soil behavior has performed for many years, but there is a review of domestic and foreign literature ash, mostly looks at the aspects of physical and chemical properties and heavy metals, there is no assessment of the casing methane oxidation impact. This paper mainly urban incinerator ash as a research object, and after a landfill cover soil mined to study experimentally analyze the impact of ash added methane oxidation right.


Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 2755-2755
Author(s):  
Jeff P. Sharman ◽  
Donald E. Tsai ◽  
Clare J. Twist ◽  
Steven M. Horwitz ◽  
Carol D. Jones ◽  
...  

Abstract Background: PTLDs are typically B-cell neoplasms occurring as uncommon but serious complications of reduced T-cell immune surveillance associated with organ transplantation. RIS benefits only a subset of PTLD patients and cytotoxic therapy may be poorly tolerated. Therefore, in October 1998 we initiated a prospective study of rituximab in patients who failed or were unable to receive RIS and now report mature results. Methods: Patients with CD20+ PTLD were eligible if they had failed to completely respond to RIS or RIS was contraindicated and had Karnofsky performance status >60, age 3–70 years (y), measurable disease, and no change in immunosuppression for at least 2 weeks and no cytotoxic therapy within 4 weeks. Rituximab was given as 375 mg/m2 weekly x 4 with disease evaluation at 1, 3, 6, 9, 12 and 18 months. Response data, survival curves, and the impact of clinical and pathological factors were evaluated. Results: 24 of 26 enrolled pt were eligible and evaluable. Median age was 42y with 5 <17 y, 18 were male, and 14 progressed on RIS. Median time to PTLD from transplant was 47 months (m) (8 <24 m). 17/22 were EBV+, 17 were large cell or Burkitt histology, and 10 PTLD occurred in the allograft site. Response rate was 63% (46 %CR, 17% PR) and CRs were durable (1/11 progressed). With median follow-up of 65 m (range 44–82), outcomes at 5 y are: overall survival 48%, freedom from progression 41% and failure-free survival 21%. 7 pt died without progression, yielding 5 y cause-specific survival of 69%. Nine of 13 pt with disease progression were successfully salvaged with second-line therapy. In univariate analysis PTLD characteristics did not significantly correlate with outcome but 2/2 Burkitt pt quickly progressed. Conclusions: Rituximab provided effective, durable treatment for ~40% of pt failing RIS in this series of mainly late PTLD and a majority of pt progressing after rituximab could be treated successfully. However, overall and failure-free survival reflect significant co-morbidity in this population.


2013 ◽  
Vol 29 (1_suppl) ◽  
pp. 37-54 ◽  
Author(s):  
Byungmin Kim ◽  
Youssef M.A. Hashash

Downhole arrays provide enhanced understanding of dynamic soil behavior and site response. Historically, downhole array recordings have been available only for earthquakes with relatively limited durations. New recordings from a number of KiK-net downhole arrays during the 11 March 2011, Mw 9.0, subduction zone earthquake near the east coast of Honshu, Japan, allow us to investigate dynamic soil characteristics and site response due to long-duration subduction zone earthquakes. Using these recordings, we perform one-dimensional site response analyses to evaluate the applicability of commonly used analysis approaches under long-duration earthquakes. We find that site response analyses capture key features of measured surface response spectra particularly at soft rock/stiff soil sites subject to long-duration motion. However, at softer soil sites, it appears that the modulus reduction is overestimated and site-specific characterization is needed.


2016 ◽  
Vol 32 (2) ◽  
pp. 1055-1074 ◽  
Author(s):  
Ramin Motamed ◽  
Kevin Stanton ◽  
Ibrahim Almufti ◽  
Kirk Ellison ◽  
Michael Willford

A nonlinear ground response analysis is conducted for the Niigata-ken Chuetsu-oki earthquake recorded at a free-field vertical array near the Kashiwazaki-Kariwa Nuclear Power Plant in Japan. A bidirectional site response analysis is carried out using LS-DYNA which allows user defined stress-strain relationships to dictate soil behavior subjected to dynamic loading. Dynamic soil behavior is characterized using a two-stage hyperbolic backbone curve implemented with modifications to consider the peak strength of soil layers as well as the strain at which the peak strength is fully mobilized. The effects of bidirectional input motions, strain rate, and the shape of the shear modulus degradation curves are investigated, and it is demonstrated that each factor can have a significant influence on the results.


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