scholarly journals Benign fibrous histiocytoma of the femur: A rare pediatric case report

2021 ◽  
Vol 9 (3) ◽  
pp. 339-344
Author(s):  
Hicham Abdellaoui ◽  
Mohammed Tazi Charqui ◽  
Fatoumata Binta Balde ◽  
Karima Atarraf ◽  
Afifi My Abderrahmane
Keyword(s):  
Fibrous Histiocytoma ◽  
Histopathological Examination ◽  
Pediatric Population ◽  
Skin Tumor ◽  
Ossifying Fibroma ◽  
Soap Bubble ◽  
Benign Fibrous Histiocytoma ◽  
Adequate Treatment ◽  
The Right ◽  
Bone Remains

BACKGROUND: Benign fibrous histiocytoma is known to be a frequent skin tumor but its occurrence in bone remains very rare especially in pediatric population. This entity is a subject of interest also because histologically it can mimic other fibrohistiocytic lesions of bone such as non-ossifying fibroma. CLINICAL CASE: An 11-year-old patient admitted with swelling of the right thigh and intermittent pain. Radiological evaluation shows cystic lesion of the femur with a soap-bubble and a border of condensation. Histopathological examination of the biopsy sample established the diagnosis of benign fibrous histiocytoma. The patient underwent complete curettage of the lesion with bone graft. There is no recurrence 16 months after surgery. DISCUSSION: Benign fibrous histiocytoma is a rare bone tumor especially in children. Histologically it can mimic non-ossifying fibroma. Thus clinical and radiological features are important to differentiate these tumors in order to choose adequate treatment. CONCLUSIONS: Benign fibrous histiocytoma is probably underestimated in pediatric population. This diagnosis should be considered in any child or teenager who presents with a non-ossifying fibroma accompanied by unexplainable pain or a rapid growing.

scholarly journals Three cases of femoral neck tumor different from benign fibrous histiocytoma or non-ossifying fibroma.

1988 ◽  
Vol 36 (4) ◽  
pp. 1496-1499
Author(s):  
Osamu Inoue ◽  
Kunio Ibaraki ◽  
Hiromichi Norimatsu ◽  
Tomoaki Yoshikawa ◽  
Satoshi Tomiyama ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Fibrous Histiocytoma ◽  
Ossifying Fibroma ◽  
Benign Fibrous Histiocytoma ◽  
Neck Tumor

scholarly journals Desmoplastic Fibroma and Cemento Ossifying Fibroma of The Anterior Maxilla: A Rare Case Report

2021 ◽  
Vol 24 (1) ◽  
pp. 21-27
Author(s):  
Victor Pakpahan ◽  
Eky Nasuri ◽  
Vera Julia
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Neck Region ◽  
The Body ◽  
Ossifying Fibroma ◽  
Desmoplastic Fibroma ◽  
Anterior Maxilla ◽  
Main Complaint ◽  
Rare Case Report ◽  
The Right

Tumors located in the maxillofacial part of the body were classified by WHO in 2017 and among these are intraosseous form of fibromatosis known as Desmoplastic and Cemento-ossifying fibromas. These tumors usually occur in the head and neck region, especially in the mandible and are relatively rare in the maxilla. Meanwhile, this study aims to discribe a rare case of the cemento ossifying fibroma that had been previously diagnosed as desmoplastic fibroma with a mass tumor in the anterior of the maxilla. A 22 years old female reported to the Cipto Mangkusumo Hospital with the main complaint of a lump in the right side of the upper jaw which appeared 2 years prior to the operation. In April 2017, the patient had a biopsy in Tarakan Hospital and the result was a desmoplastic fibroma. Due to the lump enlargement, the patient was admitted to RSCM in July 2019 and had biopsy incision with a diagnosis of cemento ossifying fibroma which was confirmed by the histopathological examination and histology report. The resection of the right part of maxilla was conducted alongside with reconstruction using the free fibular flap. Moreover, cemento ossifying fibroma and desmoplastic fibroma shared similar features, namely, clinical, histological and radiological features which are important in establishing the diagnosis and treatment of patient. Hence, extensive enucleation or resection is required due to the progressive nature of the tumor to prevent the potential for further recurrences.

scholarly journals MON-482 Thyroid Tuberculosis - An Unlikely Diagnosis

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Alexandra Novais Araújo ◽  
Tânia Matos ◽  
Ema Nobre ◽  
Maria Joao Bugalho
Keyword(s):  
Lymph Node ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Extrapulmonary Tuberculosis ◽  
Needle Aspiration ◽  
Tuberculous Infection ◽  
Rare Presentation ◽  
Adequate Treatment ◽  
Fine Needle ◽  
The Right

Abstract Background: Mycobacterium tuberculosis (MTB) is an aerobic bacillus responsible for the most cases of tuberculous infection. Approximately one-third of the world’s population is infected. Tuberculosis (TB) of the thyroid gland is an unusual diagnosis with an estimated prevalence of 0.1 to 0.6%. The thyroid TB can mimic different pathologies (thyroid neoplasms, lymphoma, infectious or granulomatous thyroiditis, Graves’ disease or bacterial abscess) and the diagnosis can be easily disregarded, especially in non-endemic countries and if the patient doesn’t have systemic symptoms. The fine needle aspiration and histopathological examination, with acid-fast bacilli staining and TB culture, are the gold standard exams. Clinical Case: A 71-year-old female was referred to our Endocrinology department after a diagnosis of nodular thyroid disease. She had complaints of slight cervical discomfort, with 6 months of duration. She hadn’t personal or familiar relevant antecedents. At observation, a movable, elastic and non-tender nodule of 15mm at the right superior thyroid lobe was identified. Blood tests including a thyroid profile were normal. The neck ultrasound showed, at the right lobe of the thyroid, multiple solid nodules; the dominant had 18mm, was heterogeneous and had multiple calcifications. Moreover, lymph nodes with suspicious ultrasonographic features along the right internal jugular chain were reported. The patient underwent fine-needle aspiration (FNA) of the suspicious thyroid nodule and one lymph node. Results were respectively: non-diagnostic (Bethesda I) and reactive pattern. FNA was repeated on a different occasion and results were similar. Due to ultrasound suspicious of malignancy, a total thyroidectomy was performed and a lymph node from level IV was sampled for extemporaneous examination. Necrotizing granulomas were documented; the Ziehl-Neelson staining (ZNS) was negative; material was sent to microbiology. Following this finding, ganglion emptying was not performed. The thyroid histology showed tuberculoid type granulomas with lymphoid border and central necrosis. However, the ZNS was negative. The diagnosis was definitely established by a positive culture of the lymph node tissue and molecular detection, by polymerase chain reaction (PCR), of MTB. Pulmonary involvement was excluded and she started antituberculous agents planned for 9 months (rifampicin and isoniazid during 9 months and ethambutol and pyrazinamide for 2 months). Conclusion: Thyroid TB is a rare presentation of extrapulmonary tuberculosis. In presence of systemic or specific complaints or history of exposition the diagnosis may be suspected and confirmatory tests requested in order to ensure an adequate treatment. However, sometimes, histopathology remains a key step and the use of cultures improves the sensitivity and specificity of TB tests.

scholarly journals Postoperative complicated appendectomy revealing Crohn’s disease in a pediatric patient

2021 ◽  
Vol 8 (1) ◽  
pp. 154-160
Author(s):  
Augustina Enculescu ◽  
Mircea Lupusoru ◽  
Catalin Cirstoveanu ◽  
Andra-Iulia Suceveanu ◽  
Liliana Andronache ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Acute Appendicitis ◽  
Histopathological Examination ◽  
Pediatric Population ◽  
Pathological Examination ◽  
Ileocecal Resection ◽  
Initial Manifestation ◽  
Adequate Treatment ◽  
Granulomatous Appendicitis

Granulomatous appendicitis is a very rare entity in children. It is related to Crohn’s disease in only 5-10% of the cases. The diagnosis of Crohn’s disease is a real challenge in the pediatric population, especially when its initial manifestation is acute appendicitis. Herein, we present a 13-year-old boy admitted for acute appendicitis. The histopathological examination was conclusive for acute granulomatous appendicitis. The development of an entero-cutaneous fistula has complicated the postoperative evolution. The failure of the conservative management required ileocecal resection. The pathological examination revealed Crohn’s disease. The one-year follow-up on the patient din not reveal any complications. We strongly support the importance of the histopathological examination of the entirely removed appendix. Careful assessment of granulomatous appendicitis is needed in order to establish its possible etiology and to initiate the adequate treatment.

scholarly journals Concomitant bilateral mandibular cemento-ossifying fibroma and cementoblastoma: case report of an extremely rare occurrence

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Madiha Bilal Qureshi ◽  
Muhammad Usman Tariq ◽  
Jamshid Abdul-Ghafar ◽  
Muhammad Raza ◽  
Nasir Ud Din
Keyword(s):  
Unusual Case ◽  
Histopathological Examination ◽  
Single Case ◽  
Ossifying Fibroma ◽  
Case Presentation ◽  
Left Posterior ◽  
Left Mandible ◽  
Left And Right ◽  
Characteristic Features ◽  
The Right

Abstract Background Cemento-ossifying fibroma (COF) and cementoblastoma (CB) are rare benign odontogenic tumors with a predilection for the mandible. Cemento-ossifying fibroma is a fibro-osseous lesion that originates in the tooth bearing areas of jaw and shows cementum-like tissue in a fibrotic stroma. Cementoblastoma is classically related to roots of teeth with the presence of calcified cementum-like material. To date, only a single case of concomitant unilateral COF and CB has been reported in the literature. Case presentation We present an unusual case of a 37-year-old female who presented with two discrete bilateral swellings in the right and left mandible for 10 years. The larger tumor involved the left posterior mandible with extension anteriorly to the left and right anterior mandibles, and the smaller tumor was present in right posterior mandible. Radiology revealed two distinct lesions involving both sides of mandible. Histopathological examination showed characteristic features of cemento-ossifying fibroma in sections of the larger tumor and cementoblastoma in sections of smaller tumor. Conclusion This case shows the very unique bilateral co-existence of COF and CB, the second case reported in literature to date.

scholarly journals Hyperpigmented Nodular Dermatofibroma: Two Cases Report and Brief Literature Review

2021 ◽  
Vol 9 (C) ◽  
pp. 198-203
Author(s):  
Andi Hardianty ◽  
Khairuddin Djawad ◽  
Siswanto Wahab ◽  
Airin Nurdin
Keyword(s):  
Fibrous Histiocytoma ◽  
Case Reports ◽  
Basal Layer ◽  
Surgical Excision ◽  
Good Prognosis ◽  
Skin Tumor ◽  
Benign Fibrous Histiocytoma ◽  
Skin Tumours ◽  
Common Skin ◽  
Slow Growing

BACKGROUND: Dermatofibroma (DF) is a common benign skin tumor (Benign Fibrous Histiocytoma) that mostly affects the extremities with a tendency to occur more often in older females than males. It usually presents as a slow growing small brown dome shape papule on the extremities. DF has a chronic nature and can sometimes regresses spontaneously. Dermoscopy is essential in the evaluation of DF to help differentiate it with other skin tumors. The gold standard evaluation for diagnosis of DF is biopsy with histopathologic examination. Removal of DF is often due to cosmetic factors, with surgical excision being the preferred method for removal. DF has an excellent prognosis. CASE REPORT: We present two case reports of women with hyperpigmented nodules on the lower extremity. Dimple sign was positive. From dermoscopic study showed a pigment network and central white patch pattern. On histologic examination revealed proliferation of fibroblast such as spindle cells as a storiform pattern and hyperplastic epidermis with hyperpigmentation of the basal layer. Based on clinical features, dermoscopy and histopathological evaluation, the diagnosis of DF was established. Both patients were perform surgically excision and have a good result. CONCLUSION: Dermatofibroma is benign fibrous histiocytoma that represents one of the most common skin tumours. Nodular hyperpigmented dermatofibroma is a clinical variant of Dermatofibroma which can be treated with surgical excision with good prognosis.

scholarly journals Benign fibrous histiocytoma of the tongue: a case report

2017 ◽  
Vol 20 (2) ◽  
pp. 152
Author(s):  
Michele Fonseca Brantes ◽  
Rebeca Souza Azevedo ◽  
Silvia Paula Oliveira ◽  
Adriele Ferreira Gouvêa ◽  
Ademar Takahama Jr
Keyword(s):  
Fibrous Histiocytoma ◽  
Histopathological Examination ◽  
Subcutaneous Tissue ◽  
Correct Diagnosis ◽  
Excisional Biopsy ◽  
Histopathological Analysis ◽  
Benign Fibrous Histiocytoma ◽  
Soft Tissue Neoplasm ◽  
Traumatic Neuroma ◽  
Spindle Cells

<p>The fibrous histiocytoma is a soft tissue neoplasm that affects the dermis and the subcutaneous tissue, rarely is found in the oral cavity and perioral regions, and is originated from the proliferation of fibroblasts and histiocytes. The objective of this paper is to report a case of Benign Fibrous Histiocytoma in a 30-year-old male patient, complaining of a painless nodule in the tongue for about six months. With the clinical diagnostic hypotheses of Fibrous Hyperplasia or Traumatic Neuroma an excisional biopsy was performed. The histopathological examination revealed a non-encapsulated proliferation of spindle cells with some giant multinucleated cells in the periphery of the lesion.  Immunohistochemical reactions were performed, staining only for vimentin in the spindle cells and for CD68 in the multinucleated giant cells. According to these characteristics, the final diagnosis was Benign Fibrous Histiocytoma. The correct diagnosis of spindle shaped cell neoplasia must be performed with the aid of histopathological analysis and immunohistochemistry, mainly because the morphological similarities with other benign and malignant lesions. </p>

scholarly journals Peripheral odontogenic myxoma: Clinical case with a literature review

2021 ◽  
Vol 10 (6) ◽  
pp. e26910615797
Author(s):  
Carlos Eduardo Nogueira Nunes ◽  
Anne Diolina Araújo Morais ◽  
João Victor Morais de Lima ◽  
Filipe Nobre Chaves ◽  
Marcelo Bonifácio da Silva Sampieri ◽  
...  
Keyword(s):  
Literature Review ◽  
Histopathological Examination ◽  
Excisional Biopsy ◽  
Final Diagnosis ◽  
Ossifying Fibroma ◽  
Histopathological Diagnosis ◽  
Odontogenic Myxoma ◽  
Long Term Follow Up ◽  
The Right ◽  
Age Range

Peripheral odontogenic myxoma (POM) is a rare and extra-osseous variant of odontogenic myxoma (OM), classified as a relatively rare benign odontogenic tumor, yet presenting locally aggressive behavior. The objective this manuscript is to report a case of POM in a 75-year-old patient, located in the right maxilla, and in addition, to perform a literature review of the data in relation to clinical, radiographic aspects, hypothesis of diagnosis, and treatment. A male patient, 75 years old, clinical examination constact the presence of a nodule, with a smooth surface, on the right upper alveolar ridge, measuring 20 x 25 mm, with a color similar to the mucosa, a softened consistency, involving teeth 14 and 15, and with an undetermined time of evolution was observed. The diagnostic hypothesis was a peripheral ossifying fibroma and differential diagnosis of peripheral giant cell lesion. An excisional biopsy was performed together with extraction of the involved teeth. Histopathological examination and histochemical reaction was confirm the histopathological diagnosis of POM. The reported case is extremely rare due to the clinical presentation of the lesion, causing bone resorption with tooth mobility. In addition, the age range of involvement is very different from that presented in the literature, between the second and fourth decade of life. The final diagnosis was very important, as it is a lesion with a great potential for recurrence, long-term follow-up should be more careful, and in case of recurrence, a new intervention must be performed.

scholarly journals Synchronous Juvenile ossifying Fibroma in maxilla and mandible- A case report

2014 ◽  
Vol 4 (2) ◽  
pp. 54-57
Author(s):  
B Shrestha ◽  
S Subedi ◽  
S Pandey
Keyword(s):  
Histopathological Examination ◽  
Ossifying Fibroma ◽  
Medical College ◽  
Appropriate Treatment ◽  
Juvenile Ossifying Fibroma ◽  
Long Term Follow Up ◽  
Maxilla And Mandible ◽  
The Right

Juvenile ossifying fibroma (JOF), one of the fibroosseous lesions is an uncommon clinical entity and involving both jaw is even rarer. Here, we present the case of a 15-year-old female patient with synchronous occurrence of JOF in the right sided maxilla and in the periapical area of mandibular right premolar molar region. After the clinical, radiographical and histopathological examination, the surgical treatment was carried out and the patient was kept under long term follow up. Owning to its aggressive local behaviour and high recurrence, early diagnosis, appropriate treatment and long term regular follow up are of prime importance. DOI: http://dx.doi.org/10.3126/jcmc.v4i2.10867 Journal of Chitwan Medical College 2014; 4(2): 54-57

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