scholarly journals Standard procedure for the pharmacotherapy of pain in childhood

2021 ◽  
Vol 9 (2) ◽  
pp. 203-209
Author(s):  
Adriana Kollerová
Keyword(s):  
Pain Relief ◽  
Acute Pain ◽  
Analgesic Effect ◽  
Standard Procedure ◽  
Age Group ◽  
Analgesic Treatment ◽  
Pain Services

Physicians of all specialties encounter patients in pain. The basis of the philosophy of caring children is not to question the existence of pain but to predict, prevent, and adequately treat it. Acute pain services implement preventive and multimodal analgesic treatment to increase the analgesic effect at the lowest possible doses to minimize undesirable effects of individual drugs. However, this service cannot be provided in all hospitals 24 hours a day. This study provides a clear, color-coded recommendation for pain relief in children, which provides a quick, rational, and safe choice of analgesics or their safe and effective combinations and dosage for each age group.

scholarly journals Is there an alternative to diclofenac i/m injections for rapid relief of severe pain? Results of randomized controlled and partially blind forsage study

2020 ◽  
Vol 58 (4) ◽  
pp. 387-394
Author(s):  
A. E. Karateev ◽  
E. Yu. Pogozheva ◽  
E. S. Filatova ◽  
A. M. Lila ◽  
V. N. Amirdjanova ◽  
...  
Keyword(s):  
Pain Relief ◽  
Pain Intensity ◽  
Acute Pain ◽  
Analgesic Effect ◽  
Rapid Onset ◽  
Significant Pain ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1 ◽  
New Onset

Diclofenac Potassium sachets (DPS) is a new faster-absorption and rapid onset of pain relief drug dosage form of Diclofenac with high analgesic potential.Objective. To assess efficacy and safety of Diclofenac sachets and intramuscular injections in relieving acute pain in patients with rheumatic diseases (RDs).Materials and methods: The study group included 30 RD patients, 53.3% females and 46.7% males, mean age 41.8 ± 10.7 years, with severe acute pain (≥7 cm VAS pain rating, VAS 0-10 cm). After signing informed consent patients were randomized into DPS 50 mg t.i.d. and Diclofenac 75 mg i/m b.i.d. The first administration of Diclofenac was blind, i.e., patients from both groups were also administered placebo – either placebo injection in Group 1 randomized to sachet or placebo sachet in Group 2. The study lasted for 3 days. Level of analgesia was assessed in 15, 30, 60, 120, 180 minutes after the first administration, then three times a day during two following days and in the morning on day 4. Serum levels of CRP, IL-6 and P substance biomarkers were also monitored.Results. Pain relief in Group 1 was documented already in 15 min after administration – from 8.1±0.8 to 5.7±1.7 cm VAS (р=0.012), with continuing increase of analgesic effect thereafter. Group 2 demonstrated significant pain relief in 1 hour after Diclofenac administration – from 7.6±0.7 to 4.5±1.9 cm VAS (р=0.04). Based on obtained data analgesic effect was more powerful in Group 1 vs Group 2 in 15 and 30 minutes after drug administration (р=0.019; р=0.037). Starting from the 3rd hour post-administration there was no statistically significant difference in pain intensity between the two groups. Final assessment in the morning on day 4 showed significant pain reduction by 4.5±2.6 cm VAS in Group 1 vs baseline, and by 3.6±1.4 cm VAS in Group 2 (p=0.545). Functional improvement in both groups reached 3.7±1.9 and 3.3±1.3 cm VAS, respectively (p=0.837). The results were rated as “good” and “excellent” by 77.0% in Group 1, and 61.5% – in Group 2 (р=0.302). No correlation between decreasing pain intensity and fluctuating CRP, IL-6, and substance P concentrations was established. Three patients from Group 1 reported new-onset dyspepsia, resulting in discontinuation of treatment in 2 of them. Similarly, 2 discontinuations occurred in 2 patients with new-onset dyspepsia in Group 2, plus one additional withdrawal due to gastric ulcer and elevated blood pressure.Conclusion. DPS is not inferior to i/m Diclofenac injections in terms of analgesic potential and rapid onset of pain relief. Oral intake is associated with fewer adverse reactions compared to i/m injections. 

A guide to epidural management

2020 ◽  
Vol 81 (1) ◽  
pp. 1-7
Author(s):  
Steve McLaren ◽  
Megan Hughes ◽  
Catherine Sheehan ◽  
Jagdish Sokhi
Keyword(s):  
High Risk ◽  
Pain Relief ◽  
Epidural Analgesia ◽  
Nursing Staff ◽  
Acute Pain ◽  
Multidisciplinary Team ◽  
Trauma Patients ◽  
Timely Fashion ◽  
Pain Services

Epidural analgesia is a key component in the management of inpatient pain relief, particularly in surgical and trauma patients, and those with comorbidities. When used appropriately epidurals can decrease a patient's opiate consumption, as well as reducing the risk of adverse cardiorespiratory outcomes. To non-anaesthetists, or those not versed in their usage, epidurals can appear complex and intimidating, and the potential complications, although rare, can be catastrophic if not picked up on in a timely fashion. This article demystifies the epidural for hospital clinicians, looking at the anatomy and pharmacology, helping to identify patients who may benefit from epidural analgesia, highlighting some common pitfalls and questions posed by nursing staff, and providing a framework via which junior clinicians can detect, manage and appropriately escalate epidural-related problems and complications. Epidural analgesia is an invasive and high-risk intervention; as such it should always be managed by a multidisciplinary team, including anaesthesia and acute pain services.

Clinico-pathological study of acute pain abdomen in paediatric age group

2019 ◽  
Vol 13 (2) ◽  
pp. 108-111
Author(s):  
Vidya M Saravagol ◽  
◽  
Deepak Shanbhag ◽  
Ashraf Ahamed ◽  
Kartik Sadananda ◽  
...  
Keyword(s):  
Acute Pain ◽  
Age Group ◽  
Pathological Study ◽  
Pain Abdomen ◽  
Paediatric Age

scholarly journals Assessment for acute pain management in post-total knee replacement (TKR): a prospective cohort study in two Saudi Arabian medical centers

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Mariam Ahmad Alameri ◽  
Syed Azhar bin Syed Sulaiman ◽  
Abdullah Moh’d Talaat Ashour ◽  
Ma’ad Faisal Al-Saati
Keyword(s):  
Cohort Study ◽  
Pain Management ◽  
Total Knee Replacement ◽  
Acute Pain ◽  
Joint Replacement ◽  
Acute Pain Management ◽  
Analgesic Treatment ◽  
Pain Management Index ◽  
Medical Centers ◽  
Total Knee

Abstract Background Acute pain in post joint replacement surgeries is common, which makes the management of acute pain following joint replacement surgeries to be very important. Thus, this study was conducted to evaluate acute pain management of post TKR surgeries. Results Patients with negative pain management index (PMI) scores were classified as receiving inadequate analgesic treatment for their pain. Zero PMI was the most frequent score among the others with 195 (80.6%). The rest were − 1 (11 (4.5%)), 1 (27 (11.2%)), and 2 (9 (3.7%)), respectively. Only 4.5% (11/242) patients have negative PMI score, which could be considered as inadequate pain management in which these patients received inadequate analgesic treatment. Conclusion Acute pain management in post-TKR surgeries in both medical centers achieved an acceptable level, and majority of patients received an adequate analgesia in post-TKR surgeries.

Comments on low cost acute pain services

Pain ◽  
1994 ◽  
Vol 59 (1) ◽  
pp. 154 ◽  
Author(s):  
J. H. Hughes
Keyword(s):  
Acute Pain ◽  
Low Cost ◽  
Pain Services

scholarly journals Understanding the challenges of service change – learning from acute pain services in the UK

2009 ◽  
Vol 102 (2) ◽  
pp. 62-68 ◽  
Author(s):  
AE Powell ◽  
HTO Davies ◽  
J Bannister ◽  
WA Macrae
Keyword(s):  
Acute Pain ◽  
The Uk ◽  
Pain Services ◽  
Service Change

666 EVALUATION OF CRITICAL INCIDENTS IN ACUTE PAIN SERVICES

2009 ◽  
Vol 13 (S1) ◽  
Author(s):  
K. Rao ◽  
C. Weetman ◽  
K. Muthusamy
Keyword(s):  
Acute Pain ◽  
Critical Incidents ◽  
Pain Services

Organization of Acute Pain Services

1994 ◽  
Vol 38 (6) ◽  
pp. 348
Author(s):  
NARINDER RAWAL ◽  
LARS BERGGREN
Keyword(s):  
Acute Pain ◽  
Pain Services
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