scholarly journals Congenital dislocation of the knee: a morphological study

2021 ◽  
Vol 8 (4) ◽  
pp. 427-435
Author(s):  
Igor Yu. Kruglov ◽  
Olga E. Agranovich ◽  
Nicolai Yu. Rumyantsev ◽  
Olga Yu. Razmologova ◽  
Andrey V. Kolobov ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Comparison Group ◽  
Knee Dislocation ◽  
Control Group ◽  
Congenital Dislocation ◽  
Autopsy Material ◽  
Anatomical Structures ◽  
Congenital Knee Dislocation ◽  
System 1 ◽  
Stillborn Fetus

Background. Congenital knee dislocation is a rare disease of the musculoskeletal system (1 in 100,000 live births). In the literature, few studies have described the anatomical changes characteristic of this pathology, which are only revealed during surgical treatment. Aim. This study aimed to evaluate the pathomorphological features of the ligamentousarticular apparatus and thigh muscles with congenital knee dislocation on autopsy material. Materials and methods. The study included two fetuses with bilateral congenital knee dislocation after spontaneous miscarriage at 18 and 20 weeks of gestation and one stillborn fetus with bilateral congenital knee dislocation at 29 weeks of gestation. The comparison group was composed of two fetuses after spontaneous miscarriages at 18 and 20 weeks of gestation and one stillborn fetus at 25 weeks of gestation without anomalies of the lower extremities. Results. Various abnormalities and displacements of the anatomical structures, as well as degenerative dystrophic changes in the soft tissues during histological examination, were found. Pathomorphological changes in the control group were not detected. Conclusion. Pathomorphological changes are the main manifestations of congenital knee dislocation in the studied fetuses.

scholarly journals Association between Abscess Fluid and Procalcitonin in Blood Serum

2020 ◽  
Vol 13 (2) ◽  
pp. 109-115
Author(s):  
Nadezhda Anatol'evna Zubareva ◽  
Dmitriy Yur'evich Sosnin ◽  
Andrey Viktorovich Renzhin
Keyword(s):  
Blood Serum ◽  
Organ Failure ◽  
Soft Tissues ◽  
Comparison Group ◽  
Statistical Significance ◽  
Abdominal Cavity ◽  
Test System ◽  
Control Group ◽  
Surgical Department ◽  
Experimental Group

Introduction. Currently there are no relevant findings from a comparative study of the chemical composition of the abscess fluid and blood serum.The aim of the research was to study the composition of procalcitonin (PCT) contained in the blood serum and abscess fluids of the soft tissues and the abdominal cavity in local inflammation and sepsis.Materials and methods. The PCT concentration was determined in blood serum and the content of abscesses of the soft tissues and abdominal cavity in 45 patients of the surgical department. The experimental group included 31 patients with inflammatory processes that did not result in the organ failure. The comparison group included 14 patients with abscesses which manifested clinical and laboratory signs of the systemic inflammation and organ failure. The control group included 25 healthy individuals. The PCT level was determined by ELISA using the Procalcitonin - ELISA - BEST test system (Vector - Best, Russia).Results. Differences in the PCT content in the serum between groups were characterized by a high degree of statistical significance (H = 58.79206, p = 0.0000). The highest PCT level in the serum was observed in patients of the comparison group, where the average values ​​were 11.94 4.98 ng / ml, the lowest PCT level in the serum was observed in patients of the control group. The PCT concentration in the content of abscesses was lower compared to blood serum and was characterized by statistically significant differences in patients of both - experimental group and comparison groups (p = 0.00001)Conclusion. Abscesses of the soft tissues and the abdominal cavity without signs of generalized infection are not accompanied by an increase in the PCT concentration in the blood serum for more than 2 ng/ml. The PCT concentration in the content of abscesses was lower than its content in the blood serum in both - the local inflammatory process and in the development of sepsis.

scholarly journals Congenital dislocation of the knee in combination with Meyer-Gorlin syndrome: A case report

2021 ◽  
Vol 9 (4) ◽  
pp. 447-454
Author(s):  
Igor Y. Kruglov ◽  
Nicolai Y. Rumyantsev ◽  
Gamzat G. Omarov ◽  
Natalia N. Rumyantseva ◽  
Ilya M. Kagantsov
Keyword(s):  
Clinical Case ◽  
Clinical Manifestations ◽  
Knee Dislocation ◽  
Congenital Dislocation ◽  
Gorlin Syndrome ◽  
Orthopedic Surgeons ◽  
First Case ◽  
Congenital Knee Dislocation ◽  
Classical Triad ◽  
Pediatric Orthopedic

BACKGROUND: Meyer-Gorlin syndrome is a rare genetic and autosomal recessive disease that is characterized by the classical triad, including, microtia, very small size or complete patellar absence, and nanism. CLINICAL CASE: Herein, presented the first clinical case description of a Russian patient with Meyer-Gorlin syndrome in combination with congenital anterior shin dislocation. The main clinical disease manifestations are characterized by a combination of microtia, patellar pathology, and dwarfism. DISCUSSION: In the practice of pediatric orthopedic surgeons, cases of congenital knee dislocations are extremely rare, especially as part of any syndromes, which cause interest in the presented clinical case publication. Our patient analysis, as well as the patients described in the literature, showed the presence of typical clinical manifestations, which allowed us to suspect the presence of Meyer-Gorlin syndrome during a clinical examination. CONCLUSIONS: This report is the first case of combined congenital knee dislocation and Meyer-Gorlin syndrome with a diagnostic triad (short stature, microtia, and patellar aplasia) in the Russian Federation. Conservative treatment with constant traction and flexion must be carefully performed to avoid complications. Without the effect of conservative therapy, surgical treatment is indicated.

Thromboembolic complications prevention in the obstetric practice

2017 ◽  
pp. 19-24
Author(s):  
O.V. Grishchenko ◽  
◽  
V.V. Bobrytska ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Comparison Group ◽  
Main Group ◽  
Control Group ◽  
Efficacy And Safety ◽  
Thromboembolic Complications ◽  
Moderate Risk ◽  
Obstetric Practice ◽  
Thrombotic Complications ◽  
And Control

The objective: To evaluate the clinical efficacy and safety of Enoxaparin-Pharmex for the prevention of thrombotic complications (pulmonary embolism) in the postoperative period in patients with moderate risk of these complications. Patients and methods. The study included 50 women after a caesarean section had an average degree of risk of pulmonary embolism. Patients were divided into the main group (n=25) and control group (n=25) in accordance with the treatment: patients of the main group received postoperative Еnoxaparin- Pharmex, group comparisons enoxaparin sodium (brand foreign manufacturer’s). Patients in both groups received the drug at a dose of 20 mg for 5 days, 1 time per day subcutaneously. Results. The research data analysis showed identity results of hemostasiogram of patients in the main group and the comparison group, no side effects after treatment in both groups. Conclusion. The clinical studies suggest the drug Enoxaparin-Pharmex is effective, safe LMWH, which can be used to prevent troboembolic complications, including post-operative treatment in obstetric practice. Spectrum of Enoxaparin-Pharmex can be extended to the prevention and treatment of thromboembolic conditions of varying severity with appropriate doses of the drug. Key words: Enoxaparin-Pharmex, prevention of pulmonary embolism.

Congenital Knee Dislocation: Which Classification to Follow?

2020 ◽  
Vol 14 (1) ◽  
pp. 58-59
Author(s):  
Punit Tiwari ◽  
Sergey S. Leonchuk ◽  
Harmeet Kaur ◽  
Gaurav Sharma
Keyword(s):  
Knee Dislocation ◽  
Congenital Knee Dislocation

Features of the course of labor in women with a history of perinatal loss

2018 ◽  
pp. 66-68
Author(s):  
L.I. Vorobey ◽  
Keyword(s):  
Premature Birth ◽  
Soft Tissues ◽  
Comparison Group ◽  
Child Death ◽  
Randomized Study ◽  
Perinatal Loss ◽  
Early Discharge ◽  
State Of Health ◽  
Repeat Pregnancy ◽  
History Of

The objective: was to determine the features of the course of labor in women with a history of perinatal lesions. Materials and methods. A prospective, concurrent, controlled, randomized study was conducted involving 68 women aged 26.8 ±0.5 years, with a gestation period of 28.1 ±0.56 weeks, 41 of whom had perinatal history lesions (main group) and comparable for anthropodemographic indicators and terms of gestation of 27 women with a repeat pregnancy without abortion or unsuccessful childbirth (child death) in the history (comparison group). Results. In the anamnestic aspect, the characteristics of pregnant women with a history of perinatal losses are a relatively shorter interval between repeated pregnancies, a more frequent development of extragenital pathology - the respiratory, nervous, endocrine, cardiovascular and orthopedic disorders, and a higher incidence of gynecological anamnesis. In the context of complications of delivery, women with perinatal losses are characterized by premature birth, anomalies of labor, early discharge of amniotic fluid, ruptures of soft tissues. Conclusion. It is necessary to make a comparative analysis of the course of pregnancy, childbirth and the state of health of newborns in women with a history of obstetrical anamnesis in connection with violations of neurovegetative regulation. Key words: perinatal losses, anamnesis, childbirth, current.

RISK FACTORS FOR REDUCING VITAMIN D SUPPLY IN ADOLESCENTS WITH ARTERIAL HYPERTENSION AND OBESITY

2021 ◽  
Vol 100 (2) ◽  
pp. 187-191
Author(s):  
S.S.K. Zeid ◽  
◽  
L.V. Yakovleva ◽  
Keyword(s):  
Vitamin D ◽  
Arterial Hypertension ◽  
Comparison Group ◽  
Vitamin D Insufficiency ◽  
Test System ◽  
White Coat Hypertension ◽  
Control Group ◽  
Internal Factors ◽  
Wide Range ◽  
Normal Body Weight

The aim of the study is to determine the contribution of external and internal factors, such as the season, body mass index (BMI), age, sex, degree of AH, the formation of insufficiency and/or deficiency of 25 (OH)D in adolescents with arterial hypertension (AH). Materials and methods: the core group consisted of 87 adolescents with primary AH, which then were divided into two subgroups depending on BMI (Subgroup 1 – overweight and obese, Subgroup 2 – with normal body weight). The control group consisted of 23 adolescents with the phenomenon of «white coat hypertension» (WHT). The level of 25(OH)D in the blood serum was determined by immunoextraction with further with further quantitative determination by enzyme immunoassay using StarFax 2100 analyzer (USA). A DIA source Immuno assays S.A. test system. (Belgium) was used. All calculations were carried out according to the instruction in which the norm was 25(OH)D>/=30–100 ng/ml; insufficiency – 10–29 ng/ml; deficiency – > 10 ng/ml. Results: the level of 25(OH)D in peripheral blood fluctuated in a wide range – from 5,1 to 50,2 ng/ml, the median level of 25(OH)D was 17,8 ng/ml [12,2; 23,5]. According to the results of the study, only 4 (3,6%) children had a normal vitamin D level, 95 (86,4%) had vitamin D insufficiency and 11 (10%) had a deficiency. The median values of 25(OH)D in children of the comparison group were statistically significantly higher than in children with AH of the 1st and 2nd subgroups – 23,3 ng/ml [20,8; 26,0], 14,9 ng/ml [10,8; 19,5] and 17,1 ng/ml [11,8; 23,7], respectively, p=0,001. Conclusion: according to the results of the multivariate analysis, 25(OH)D in the observed adolescents depends on many factors, such as age (6,7%), gender differences (5,7%), etc. The seasons have the greatest influence on its level (62,3%) and BMI (21,4%), the least – AH (3,9%).

The treatment effi cacy of disturbed swallowing function in patients with ischemic stroke and neurogenic dysphagia

2021 ◽  
Vol 26 (3) ◽  
pp. 51-57
Author(s):  
V. I. Ershov ◽  
A. A. Borzdyko ◽  
V. V. Silkin
Keyword(s):  
Ischemic Stroke ◽  
Combination Therapy ◽  
Comparison Group ◽  
Dynamic Assessment ◽  
Control Group ◽  
Training Method ◽  
Severity Scale ◽  
Neurogenic Dysphagia ◽  
Swallowing Function ◽  
Penetration Aspiration Scale

The aim. To evaluate the effi cacy of swallowing recovery of patients with ischemic stroke carried out with the use of training rehabilitation method using special nutrient mixtures as part of combination therapy. Material and methods. The study included 65 patients (35 men and 30 women, aged 45 to 80 years) with dysphagia in the acute period of ischemic stroke. Thirty patients (control group) were treated with special binding compounds as part of a combination therapy. Thirty fi ve patients (comparison group) did not use the mixture. The dynamics of the recovery function of swallowing using the Penetration–Aspiration Scale (PAS) and the Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS), as well as the transition from tube to independent feeding were studied. Results. The training method of rehabilitation using special nutritional mixtures is eff ective assessed with PAS and FEDSS in patients with ischemic stroke and neurogenic dysphagia (p < 0.05). The most pronounced eff ect was achieved in the group of patients with pseudobulbar syndrome. In patients with bulbar syndrome no statistically signifi cant diff erences were observed in the dynamic assessment of the severity of dysphagia on the PAS and FEDSS scales. The application of the training method leads to a signifi cantly better transition from tube to independent feeding. Conclusion. The training method of rehabilitation using special nutritional mixtures is eff ective in patients with ischemic stroke and neurogenic dysphagia and leads to a signifi cantly better transition from tube to independent feeding.

scholarly journals Effects of an attachment-based intervention on the cortisol production of infants and toddlers in foster care

2008 ◽  
Vol 20 (3) ◽  
pp. 845-859 ◽  
Author(s):  
Mary Dozier ◽  
Elizabeth Peloso ◽  
Erin Lewis ◽  
Jean-Philippe Laurenceau ◽  
Seymour Levine
Keyword(s):  
Foster Care ◽  
Developmental Education ◽  
Cognitive Skills ◽  
Comparison Group ◽  
Control Group ◽  
Strange Situation ◽  
Initial Values ◽  
Children In Foster Care ◽  
Control Intervention ◽  
And Behavior

AbstractStudies with nonhuman primates and rodents, as well as with human children, have suggested that early separations from caregivers are often associated with changes in the functioning of the hypothalamus–pituitary–adrenal (HPA) axis. On the basis of these findings, we designed a relational intervention that was intended to normalize HPA functioning among children in foster care. This paper presents findings from a randomized clinical trial that assessed the effectiveness of a relational intervention (Attachment and Biobehavioral Catch-up [ABC]) with regard to HPA functioning. The ABC intervention was intended to enhance children's ability to regulate physiology and behavior. The control intervention (Developmental Education for Families) was intended to enhance children's cognitive skills. A comparison group of children who had never been in foster care was also included. Children's cortisol production was assessed upon arrival at the lab, and 15 and 30 min following the Strange Situation. Random effects analyses of variance were performed to assess differences in initial values and change between children in the two intervention groups. Children in the ABC intervention and comparison group children showed lower initial values of cortisol than children in the treatment control group, considering arrival at lab as initial values (p < .05). Groups did not differ significantly in change over time. These results suggest that the ABC intervention is effective in helping children regulate biology in ways more characteristic of children who have not experienced early adversity.

scholarly journals The use of Portland cement in the repair of mandibular fractures in rats

2011 ◽  
Vol 26 (6) ◽  
pp. 426-432
Author(s):  
Reginaldo Inojosa Carneiro Campello ◽  
Belmiro Cavalcanti do Egito Vasconcelos ◽  
Gerhilde Callou Sampaio ◽  
Antonio Rolim ◽  
Gabriela Granja Porto
Keyword(s):  
Portland Cement ◽  
Bone Healing ◽  
Soft Tissues ◽  
Lethal Dose ◽  
Mandibular Fracture ◽  
Point Of View ◽  
Control Group ◽  
Mandibular Fractures ◽  
Male Wistar Rats ◽  
Experimental Group

PURPOSE: To evaluate the bone healing of mandibular fractures following the use of Portland cement. METHODS: Thirty-two male Wistar rats were divided into control and experimental groups. In the control group the rats were submitted to a mandibular fracture, which was reduced, and the soft tissues were sutured. In the experimental group the rats had the mandibular fracture reduced and maintained with the Portland cement. The animals were euthanized 7 and 21 days after surgery by injecting a lethal dose of anesthetic. The following variables were studied: weight of the animals, radiographic images, histopathological features and time of surgery. RESULTS: A weight loss was observed in the specimens of both groups at the different times of evaluation, a greater difference in weight before and after surgery being found in the experimental group, which was statistically significant (p <0.05, p = 0.041). From the histological point of view, with a margin of error (5.0%) the only two significant differences (p <0.05) recorded in the variables were "Material deployed" and "Bone resorption" during the evaluations at 7 and 21 days, respectively. CONCLUSION: The Portland cement served to promote bone healing.

scholarly journals Enhancing learning potential score in EFL listening comprehension and self-regulation through self-regulated dynamic assessment procedures

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Parisa Abdolrezapour ◽  
Nasim Ghanbari
Keyword(s):  
Listening Comprehension ◽  
Comparison Group ◽  
Dynamic Assessment ◽  
Self Regulation ◽  
Control Group ◽  
Assessment Procedure ◽  
Learning Potential ◽  
Theoretical Understanding ◽  
Efl Learners ◽  
Assessment Procedures

AbstractThis study aimed to integrate self-regulation strategies into dynamic assessment procedures of listening comprehension in an EFL setting and examine the possibility of raising EFL students’ listening comprehension and self-regulation skills. In addition, it explored the possibility of enhancing EFL learners’ potential scores in listening comprehension and self-regulation through applying self-regulation activities as a tool for motivating learners while being assessed. The assessment procedure was based on Vygotsky’s notion of the zone of proximal development and self-regulated intervention. The participants were 49 Iranian EFL learners in three groups: a control group, which received the institute’s regular instructional activities; a comparison group, which received dynamic assessment (DA); and an experimental group which received self-regulated dynamic assessment (SR-DA) procedures, in the form of an intervention focusing on cognitive, emotional, and behavioral self-regulation states of learners. Results of the study pointed to the potential of SR-DA for enhancing the students’ learning potential over and beyond that which is available from the DA (as offered to the comparison group) and the static testing (as offered to the control group). The results have important implications for a theoretical understanding of the mechanisms through which EFL learners develop necessary self-regulation skills in the EFL context.

Sign in / Sign up

Export Citation Format

Share Document