scholarly journals Surgical treatment of newborns with small bowel atresia (literature review)

2020 ◽  
Vol 10 (4) ◽  
pp. 473-486
Author(s):  
Natalya Y. Batchenko ◽  
Olga G. Mokrushina ◽  
Alania A. Gogichaeva

Intestinal atresia is a congenital obstruction of the lumen of the jejunum or ileum and is one of the most common causes of congenital obstruction in newborns. This literature review is devoted to the surgical treatment of newborns with various types intestinal atresia. Causes of intestinal atresia are considered, where a special role is assigned to the genetic theory, the expression of the nucleotide sequences ITGA2 873G/A and NPPA 2238T/C and antenatal circulatory disorders of the developing intestine. Topographical-anatomical and morphological characteristics of the intestine in newborns with intestinal atresia are studied in detail in articles. A table of revealed histomorphological features of the small intestine in children with atresia was compiled. In addition, processes occurring in the mucosa, submucosa, muscle, and serous membranes are described in detail. A relationship was found related to the size of the atresia site and duration of ischemia. The theory of neuromuscular regulation of the intestine is considered, in which an important role is assigned to interstitial pacemaker cells of Cajal. Variants of anastomosis depending on the difference in diameters of the adductor and excretory parts of the intestine are analyzed, and results of treatment in patients with laparoscopic access are described. The postoperative course of disease, development of complications, recurrent operative interventions, duration of parenteral nutrition, and onset of enteral load was evaluated. Conclusion. The choice of surgical technologies used to restore the patency of the intestinal tube is determined by the degree of discrepancy between diameters of anastomosed segments. The prognosis is not determined by tactics of surgical treatment, type of atresia, time before treatment, and presence of associated anomalies.

2019 ◽  
Vol 21 (4) ◽  
pp. 19-24
Author(s):  
K V Lipatov ◽  
Yu E Cherkasov ◽  
V I Khrupkin ◽  
M V Lysenko ◽  
E I Dekhissi

Analyzed the features of the surgical treatment of carbuncles. The severity of the purulent-necrotic process was assessed, the significance of the timely diagnosis of the inflammatory stage and the choice of the timing of surgical treatment is shown. The features of the options of surgical tactics - from gentle to radical surgical interventions, methods of intraoperative assessment of tissue viability in the inflammatory focus are described. The necessity of a differentiated approach to the treatment of carbuncles depending on the stage of the disease, the prevalence of the pathological process and its localization is substantiated. The significance of restorative skin-plastic surgery in the replacement of postnecrectomy defects of epithelial tissues in the treatment of extensive carbuncles is shown. Ways of improving the results of treatment of patients with carbuncles are outlined, including timely diagnosis, a differentiated approach to surgical treatment, rational antibacterial therapy, and adequate general treatment.


2020 ◽  
pp. 7-12
Author(s):  
O. Bodnar ◽  
◽  
L. Vatamanesku ◽  
B. Bodnar ◽  
M. Khoma ◽  
...  

Introduction. Small intestine atresia is one of the most common causes of low bowel obstruction in newborns. Mortality in this pathology ranges from 5 to 60%, depending on the country. Modern views about surgical correction are rather contradictory. Purpose. To analyze the surgical treatment of small intestine atresia in the surgical department of the City Children’s Hospital No. 1 ССH) (Chernivtsi, Ukraine) and the surgical department Saint Damien Pediatric Hospital NPH (SDH) (Port-o-Prence, Haiti). To determine the best methods of surgery. Materials and methods. The surgical treatment of 15 children under the conditions of SDH (Haiti) and 12 children under conditions of the city children’s clinical hospital (CCH, Chernivtsi) with atresia of the small intestine was analyzed. Determined the effectiveness of closed (oblique «end-to-end» anastomosis, taping with «end-to-end» anastomosis, Denis-Brown and Louw anastomoses), discharging (U- and T-shaped, taping with anostomosing and suspended proximal enterostoma), anastomoses and stomas (end, double, according to Mikulich). Mortality with limited parenteral nutrition was 40% (SDH), with the presence of parenteral nutrition – 33.33% (ССH, Chernivtsi). Results. According to the analyzed data, we believe that the use of the method of surgical treatment should correspond to the type of atresia, the distance of the blind proximal end from the Treitz ligament, the difference in the diameters of the adducting and abducting sections, the possibility of parenteral nutrition, and the threat of short bowel syndrome (SCS). Conclusions. Y-shaped discharging anastomosis «side-to-side» with the removal of the proximal area in the form of a stoma, can be the method of choice in case of significant difference between the intestinal diameters. It provides a wide area of the small bowel junction, chyme abduction until the fistula heals, and can be used for different types of small bowel atresia. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution. The informed consent of the patient was obtained for conducting the studies. Keywords: small intestine atresia, surgical treatment, children.


2021 ◽  
Vol 28 (1) ◽  
pp. 65-76
Author(s):  
Mikhail A. Panin ◽  
Nikolay V. Zagorodniy ◽  
Medetbek D. Abakirov ◽  
Andrey V. Boyko ◽  
Danila A. Ananyin

Avascular necrosis (AVN) of the femoral head is a disease, characterized by the death of osteocytes and bone marrow, leading to collapse of the femoral head and dysfunction of the hip joint. There are many known risk factors for the development of this disease including trauma of the hip joint, hemoglobinopathy, alcoholism, taking corticosteroids, collagenosis, etc. Conservative treatment (drug therapy using vascular drugs, bisphosphonates, chondroprotectors, NSAIDs, physiotherapy, exercise therapy) is shown for any stage of the hip AVN, however, surgical treatment has a higher potential. The key to successful treatment is the detection of AVN at an early (pre-collapse) stage to prevent subsequent collapse by performing organ-sparing surgical interventions that reduce the rate of disease progression and allow delaying of the hip replacement. The literature describes a number of organ-preserving operations performed at an early stage of AVN. Currently, there are three main areas of surgical treatment of this disease: classical decompression of the femoral head, decompression using various types of grafts and combined treatment using various cellular technologies. This literature review is devoted to the consideration of the indications for implementation, as well as the results of treatment of patients using the above techniques.


Distant hybridization is known to play an important role in expanding the gene pool of any crop. It is believed that the combination of different genomes in one nucleus, as a rule, is accompanied by the phenomenon of “genomic shock”, resulting in a variety of genetic and epigenetic changes. This provides a wealth of material for the selection of genotypes adapted to different environmental conditions. Interspecific hybrids in different combinations were obtained in the genus Brassica, however, until now, interest in distant hybridization in this genus has not died out, since such important crops as rapeseed and mustard demand an improvement of many important agronomic traits. The aim of this work was to study the degree of manifestation of morphological characters of a leaf, flower, and plant as a whole in the hybrid obtained by crossing of brown mustard of the variety Slavyanka and a collection specimen of spring rape. Seeds were sown in the spring of 2019 in a field with 30 cm row width. During the flowering period a number of morphological characters of a flower, leaf, and the whole plant were analyzed. Each parameter was evaluated with 10 plants. The degree of dominance in first-generation hybrid was calculated by the formula of Beil, Atkins (1965). The dominance coefficients were not determined in the case when the difference between the parental samples was insignificant. Differences between parental samples were determined by Student t-test. The level of heterosis was calculated according to the formula of Rasul et al (2002). In a mustard-rapeseed hybrid, the size of the leaves of the lower row was inherited by the type of rapeseed, which had larger leaves than mustard. The height of the hybrid plant was inherited by the type of mustard (hp = 1.32, Ht = 4.89%), and intermediate inheritance was observed for the length of the internodes (hp = -0.48). The size of the flower petals and sepals was inherited by the type of rapeseed, and significant heterosis was observed for the length of the pistil (Ht = 33.57%). The data obtained are of interest for understanding the interaction of genes of different genomes in the genus Brassica.


Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2581
Author(s):  
Michala Skovlund Sørensen ◽  
Michael Mørk Petersen

The current era within the field of surgical treatment of metastatic bone disease (MBD) is best described as the beginning of a paradigm shift [...]


2021 ◽  
pp. 153857442110024
Author(s):  
Rozina Yasmin Choudhury ◽  
Kamran Basharat ◽  
Syeda Anum Zahra ◽  
Tien Tran ◽  
Lara Rimmer ◽  
...  

Over the decades, the Frozen Elephant Trunk (FET) technique has gained immense popularity allowing simplified treatment of complex aortic pathologies. FET is frequently used to treat aortic conditions involving the distal aortic arch and the proximal descending aorta in a single stage. Surgical preference has recently changed from FET procedures being performed at Zone 3 to Zone 2. There are several advantages of Zone 2 FET over Zone 3 FET including reduction in spinal cord injury, visceral ischemia, neurological and cardiovascular sequelae. In addition, Zone 2 FET is a technically less complicated procedure. Literature on the comparison between Zone 3 and Zone 2 FET is scarce and primarily observational and anecdotal. Therefore, further research is warranted in this paradigm to substantiate current surgical treatment options for complex aortic pathologies. In this review, we explore literature surrounding FET and the reasons for the shift in surgical preference from Zone 3 to Zone 2.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Cun Li ◽  
Zonggui Huang ◽  
K. C. Anil ◽  
Chendeng Lao ◽  
Qianghua Wu ◽  
...  

Abstract Background Heterotopic ossification (HO) is noted most frequently in periarticular muscles and has not yet been reported in the cruciate ligaments of the knee. We present a rare case of symptomatic ossification of the posterior cruciate ligament (PCL). Case presentation A 59-year-old woman had a 2-year history of knee pain that was getting worse during knee motion and had restricted knee motion for 1 year. X-rays could not show the lesion clearly. Multi-planar computed tomography demonstrated ossification within the PCL with mild osteoarthritic changes and excluded any other intra-articular pathology. The patient underwent arthroscopic debridement and then experienced immediate relief of pain and complete recovery of range of motion. Conclusion This is the first report of HO in the PCL as a possible cause of knee pain and restricted knee motion. On the basis of literature review, this case elaborates the difference between HO and calcification in the ligaments, the related factors inducing HO and the undefined pathogenesis, and favorable prognosis after adequate treatment.


2021 ◽  
pp. 014556132110002
Author(s):  
Aleksander Zwierz ◽  
Krystyna Masna ◽  
Paweł Burduk

Most reported cases of middle ear adenoma (MEA) have focused on histopathology because MEA is usually diagnosed postoperatively, which is considered as a major setback. We focused on the surgical aspect of the disease to facilitate a preoperative diagnosis, resulting in prompt and proper treatment, without requiring a second stage of surgical treatment. In this report, we present the differential diagnoses in a 40-year-old man with MEA requiring surgical treatment. Preoperatively, the patient was suspected to have an MEA. An analysis of the surgical procedures in similar misdiagnosed tumors has enabled us to assess surgical procedures in cases wherein the preoperative diagnosis does not coincide with the postoperative histopathological results.


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