scholarly journals Basic clinicolaboratory and genetic characteristic of patients with mucoviscidosis living in Perm krai, other regions of Privolzhsky federal district and Central federal district of Russia

2020 ◽  
Vol 37 (1) ◽  
pp. 48-62
Author(s):  
V. V. Shadrina ◽  
E. I. Kondratieva ◽  
E. G. Furman ◽  
E. L. Amelina ◽  
M. A. Starinova ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Federal District ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Central Federal District ◽  
Perm Krai ◽  
Federal Districts ◽  
Chuvash Republic ◽  
And Migration ◽  
Epidemiological Characteristics

Aim. The project National Register of Patients with Mucoviscidosis (MV), introduced in Russia, opened the widest perspectives for comparative analysis and summarizing of clinico-epidemiological data all over Russia, federal districts, regions and separate territories. The register data permit to generalize the experience of observation and management of MV patients in centers. Comparative analysis of the clinico-epidemiological characteristics of MV and volume of therapy in patients living in Perm Krai (PK) with the other regions of Privolzhsky Federal District (PFD) and Central Federal District (CFD) of Russia was carried out. Materials and methods. According to the Register of MV Patients in the Russian Federation for 2017, the data of 1576 patients with MV were analyzed: 930 (59.0 %) patients were observed in CFD, 600 (38.1 %) in PFD, 46 (2.9) in PK. Results. Among MV patients in PFD and PK, there was noted a great variety of variants of the gene CFTR, associated with both the presence of autochthonic and relatively closed ethnic groups and migration of the population. A high allele frequency of the variant E92K was revealed in patients of Chuvash Republic (55.3 %). A group of patients from PK, registered in 2017, had a low mean age, the lowest age of making a diagnosis. Conclusions. Clinico-epidemiological studies, according to the data of MV patients register, permitted to detect some peculiar features that can be significant for practical healthcare. Further studies on MV patients register should be continued.

Comparative analysis of maternal mortality in the Far Eastern and Siberian Federal Districts

2020 ◽  
Vol 19 (6) ◽  
pp. 117-123
Author(s):  
T.E. Belokrinitskaya ◽  
◽  
N.V. Artymuk ◽  
O.S. Filippov ◽  
E.M. Shifman ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Maternal Mortality ◽  
Causes Of Death ◽  
Federal District ◽  
Siberian Federal District ◽  
Obstetric Hemorrhage ◽  
Maternal Deaths ◽  
Federal Districts ◽  
Systematic Development ◽  
Far Eastern

Objective. To perform comparative analysis of parameters and structure of maternal mortality (MM) in the Far Eastern Federal District (FEFD) and Siberian Federal District (SFD) in 2014–2019. Materials and methods. The database for analysis was generated using map-based emergency notifications of maternal deaths (69 in FEFD and 180 in SFD). We used methods of descriptive statistics, Pearson's χ2-test, and calculated odds ratios (ORs) with 95% confidence intervals (95% CIs). Results. Between 2014 and 2018, the dynamics of MM in the FEFD and SFD had a one-way trend: it decreased in 2014–2017, but dramatically increased in 2018 primarily due to social factors. In 2019, we observed a significant growth of MM in the FEFD, while the SFD demonstrated a reduction of MM. The most common cause of maternal death in both districts was extragenital diseases. However, there were some differences in the structure of obstetric causes: in FEFD, preeclampsia and obstetric hemorrhage were the most frequent obstetric causes of death, while in SFD, women primarily developed embolism and placental abruption. Conclusion. The dynamics and structure of MM in the FEFD and SFD require management decisions aimed at improving medical care with the consideration of clinical guidelines, organization of continuous audit, systematic development of practical teamwork skills both in simulation training centers and healthcare institutions. Key words: Far Eastern Federal District, maternal mortality, Siberian Federal District

scholarly journals MORBIDITY WITH TEMPORARY LOSS OF WORK CAPACITY IN WORKING POPULATION: FEDERAL AND REGIONAL INDICES AND TRENDS OVER 2005 - 2014

2019 ◽  
Vol 96 (11) ◽  
pp. 1054-1059 ◽  
Author(s):  
Natalia A. Lebedeva-Nesevrya ◽  
V. G. Kostarev ◽  
N. V. Nikiforova ◽  
M. Yu. Tsinker
Keyword(s):  
Incidence Rate ◽  
Age Groups ◽  
Federal District ◽  
Work Capacity ◽  
Working Population ◽  
Managerial Decisions ◽  
Perm Krai ◽  
Federal Districts ◽  
High Incidence Rate ◽  
Regional Product

The article presents data on morbidity with temporary loss of work capacity (MTLWC) among working population in the whole of the Russian Federation and federal districts throughout the period from 2005 to 2014. According to official statistics, common number of losses of working days is shown to decline with a rate of about 1.1-1.3% per year mainly due to a reduction in the number of cases of diseases. The Urals and Privolzhsky Federal Districts are characterized by highest rates both of the incidence rate and the number of days of MTLWC. For the example, the Perm Krai (Privolzhsky Federal District) as a region with a typical MTLWC structure was shown to represent greatest losses of working days in the age groups of 25-29 and 50-54 years of workers of both genders. The consistent high incidence rate of injuries, poisoning and other effects of external influences in working men under the age of 24 years is of particular concern. The situation testifies the need to create targeted programs to prevent diseases in young workers, who in subsequent years will form the bulk of the country’s productive forces. At the regional level MTLWC is established to account for an annual loss of about 1.3-1.5% of the gross regional product. The adoption of effective managerial decisions to reduce MTLWC is shown to allow solve not only medical and demographic, but also economic problems in certain regions and the country as a whole.

Comparative assessment of the dynamics of investment efficiency in fixed capital at the level of federal districts of Russia

2016 ◽  
Vol 11 (2) ◽  
pp. 163-170
Author(s):  
Барбашова ◽  
Ekaterina Barbashova ◽  
Лясковская ◽  
Olga Lyaskovskaya ◽  
Абрамова ◽  
...  
Keyword(s):  
Foreign Trade ◽  
Federal District ◽  
Comparative Assessment ◽  
Regional Level ◽  
Fixed Capital ◽  
Investment Efficiency ◽  
Economic Activities ◽  
Central Federal District ◽  
Federal Districts

The article proposes an approach to the determination of investment efficiency at the regional level and provides a comparative assessment of investment efficiency in different economic activities.The assessment of investment efficiency is preceded by the analysis of GRP structures and investments in the economy of the Central Federal District in the context of foreign trade, which allows to identify and then to give a comparative assessment of investment efficiency in fixed capital in the two leading types of economic activities on the share of GRP in the Central Federal District in 2005 and 2012: trade and processing production.The instruments for analysis became a package of statistical programs SPSS Statistics 22.

scholarly journals Comparative analysis of maternal mortality indices in Perm Krai over the past 20 years

2018 ◽  
Vol 35 (5) ◽  
pp. 57-62
Author(s):  
M. M. Padrul ◽  
E. V. Cherkasova ◽  
V. V. Skryabina ◽  
S. N. Berseneva
Keyword(s):  
Comparative Analysis ◽  
Maternal Mortality ◽  
Statistical Data ◽  
Federal District ◽  
Mean Value ◽  
Data Intensive ◽  
The Past ◽  
Perm Krai ◽  
The Russian Federation ◽  
The Mean

Aim. To compare the maternal mortality (MM) indices in Perm Krai with MM indices in the Russian Federation (RF) and Privolzhskiy Federal District over the past 20 years. Materials and methods. On the basis of official statistical data, intensive indices and image indices, mean multiyear MM indices, 95 % confidence intervals, median, 25 and 75 percentile indices were calculated. The mean multiyear indices are presented as M (mean value) ± SD (standard deviation). Results. According to official statistical data, the mean multiyear (1997–2016) indices of MM coefficient in Perm Krai tend to decline, but they do not reliably differ from the analogous indices in RF. During the last 20 years, there was noted a steady and obvious decrease in MM index on the territory of Perm Krai, especially marked for the last 2 years (2015–2016) that resulted in appearance of statistically significant differences regarding this index in Perm Krai compared to these indices in RF as a whole. Conclusions. Perm Krai is a rather favorable region as far as rendering of medical aid to pregnant, parturient women and puerperas is concerned.

scholarly journals Etiologic and clinical epidemiological features of hemorrhagic fever with renal syndrome (HFRS) in the Krasnodar Krai

2016 ◽  
Vol 21 (1) ◽  
pp. 22-30
Author(s):  
E. A Tkachenko ◽  
V. G Morozov ◽  
T. K Dzagurova ◽  
Yu. V Yunicheva ◽  
O. M Pilikova ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Clinical Laboratory ◽  
Hemorrhagic Fever ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Elisa Method ◽  
Krasnodar Krai ◽  
Epidemiological Features ◽  
Rural And Urban ◽  
European Part Of Russia

The purpose of the study is the investigation of etiological, clinical and epidemiological features of HFRS, caused by Sochi virus in the Krasnodar area, as well as a comparative analysis of the data with those of HFRS, caused by Kurkino virus in the Central Russian regions and Puumala virus in the areas of Volga region. Materials and methods For the identification of HFRS patients, sera from more than 800 acute febrile patients residing in Krasnodar area were examined for hantavirus antibody by IFA with Puumala, Hantaan, Seoul, Sochi, Kurkino and Dobrava viruses. For primary screening there was used the indirect immunofluorescence (ELISA) method with polyvalent cultural antigen as for serotyping of positive sera according to affiliation of antibodies to various Hantaviruses species, there were used ELISA method with monovalent cultural antigens and the neutralization reaction with Puumala, Hantaan, Seoul, Sochi, Kurkino and Dobrava viruses with the use of the method of Inhibition of Focus-Forming Units assay. Clinical and epidemiological studies have been performed on the base of history cases and records of the epidemiological examination. Results of the study. During 2000 - 2013 there were identified 64 patients suffered from HFRS caused by the Sochi virus. The patients resided in 36 settlements of 10 administrative districts of the Krasnodar area. A comparative analysis of clinical, laboratory and epidemiological data of patients with HFRS-Sochi, HFRS-Kurkino and HFRS-Puumala viruses allowed to reveal differences between the clinical (frequency of registration and severity of several symptoms, severity of the course and mortality rate) and epidemiological (prevalence in rural and urban residents, occupational pattern, the seasonality of the disease, conditions of contamination) manifestations. Conclusion There was established the etiological and epidemiological importance of Sochi virus. Sochi virus causes sporadic annual incidence of HFRS in the territory of Krasnodar area. Cases of HFRS caused by the Sochi virus are differ in more severe course of the disease and high lethality rate in comparison with the other two forms of HFRS caused by Puumala and Kurkino viruses in the territory of the European part of Russia.

scholarly journals Comparative analysis of the dynamics of obesity incidence rates in the Moscow Region population

2021 ◽  
Vol 65 (4) ◽  
pp. 318-324
Author(s):  
Olga M. Mikailova
Keyword(s):  
Comparative Analysis ◽  
Russian Federation ◽  
Age Groups ◽  
Endocrine System ◽  
Federal District ◽  
Incidence Rates ◽  
Moscow Region ◽  
Central Federal District ◽  
Adolescents And Adults ◽  
The Russian Federation

Introduction. One of the mechanisms for implementing the state policy targets in achieving wellbeing, improving the quality and duration of active life, reducing mortality, including at working age, is to reduce risks and eliminate factors that contribute to the development of obesity. The aim of the study is a hygienic assessment of the indicator of the primary morbidity of obesity in the population of the Moscow Region, the Central Federal District (CFD), the Russian Federation (RF). Materials and methods. The research materials were the databases of the regional information fund for social and hygienic monitoring of the Moscow Region for 2011-2019 (2020). The study was performed by a retrospective comparative analysis of intensive indicators of the primary morbidity of obesity in three age groups, calculated for 100 thousand cases of the corresponding age. Results. Obesity of the population of the Moscow Region occupies a significant share in the structure of diseases of the endocrine system, eating disorders and metabolic disorders. Among children, the incidence is 34.1% of all diseases of this class, among adolescents - 44.2%, adults-21.4%. The incidence of obesity among all age categories of the population of the Moscow Region is significantly lower than the level of the same indicator for the Central Federal District and for the Russian Federation, excluding the period 2011-2014, when the incidence of adolescents in the Moscow Region was higher or at the level of the indicator values for Russia. In 2019. among the 18 subjects of the Central Federal District, the Moscow Region occupies the 16th rank position in descending order of the value of the indicator of obesity among adolescents and adults for the first time. The lowest indicator for the Central Federal District is established among children. Conclusion. The implementation of the measures of the federal project “Strengthening Public Health” aimed at providing the population with a full, balanced, rational diet will reduce the risk of alimentary diseases, including obesity.

scholarly journals Epidemiology Survey of Measles in Kazakhstan

2021 ◽  
Vol 9 (B) ◽  
pp. 704-710
Author(s):  
Aygerim Zhuzzhasarova ◽  
Dinagul Baesheva ◽  
Bayan Turdalina ◽  
Aliya Seidullaeva ◽  
Alena Altynbekova ◽  
...  
Keyword(s):  
Measles Virus ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Active Immunization ◽  
World Health ◽  
The Republic ◽  
And Gender ◽  
Health Organization ◽  
Public Health Protection ◽  
Epidemiological Characteristics

BACKGROUND: Measles (rubella) is a highly contagious disease that is caused by a virus in the Paramyxoviridae family. The measles virus is directly responsible for more than 100,000 deaths each year. Epidemiological studies have linked measles to increased morbidity and mortality many years after infection, but the reasons underlying this phenomenon are poorly understood. The virus attacks immune cells, causing acute suppression of the immune system. The World Health Organization recommends a two-dose vaccination policy, with the first dose administered during the 1st year of life, and coverage should be maintained in at least 90–95% of the population to halt transmission. In many countries, the measles vaccine is included in the immunization program and is freely available to all. Today, despite active immunization of the population, measles still occurs in the Republic of Kazakhstan. AIM: The objective of our study was to analyze the epidemiological characteristics of measles in the Republic of Kazakhstan during the rise of the disease. METHODS: Statistical data were obtained from the Committee on Public Health Protection on the incidence of measles in The Republic of Kazakhstan for the period from November 1, 2018 to December 30, 2019. STUDY DESIGN: Epidemiology survey. RESULTS: The article contains epidemiological data on the incidence of measles in the regions of the Republic of Kazakhstan among children, age, and gender characteristics. CONCLUSION: In the period from November 2018 to December 2019, there was a tendency to increase the incidence of measles in the republic. In terms of morbidity, Nur-Sultan was the leader, where the number of cases was 22.9% (n = 3181). The largest number of registered cases, 58.2% (n = 5745), occurred in children aged 1–14 years. Measles remains an unresolved global problem and groups of undervaccinated and unvaccinated populations remain vulnerable during epidemics.

scholarly journals HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia

Viruses ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 475 ◽  
Author(s):  
Madita Schlösser ◽  
Vladimir V. Kartashev ◽  
Visa H. Mikkola ◽  
Andrey Shemshura ◽  
Sergey Saukhat ◽  
...  
Keyword(s):  
Low Frequency ◽  
Federal District ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Heterosexual Contact ◽  
Hiv Epidemiology ◽  
Subtype B ◽  
Accurate Knowledge ◽  
Systematic Identification ◽  
Hiv 1

Russia has one of the largest and fastest growing HIV epidemics. However, epidemiological data are scarce. Sub-subtype A6 is most prevalent in Russia but its identification is challenging. We analysed protease/reverse transcriptase-, integrase-sequences, and epidemiological data from 303 patients to develop a methodology for the systematisation of A6 identification and to describe the HIV epidemiology in the Russian Southern Federal District. Drug consumption (32.0%) and heterosexual contact (27.1%) were the major reported transmission risks. This study successfully established the settings for systematic identification of A6 samples. Low frequency of subtype B (3.3%) and large prevalence of sub-subtype A6 (69.6%) and subtype G (23.4%) were detected. Transmitted PI- (8.8%) and NRTI-resistance (6.4%) were detected in therapy-naive patients. In therapy-experienced patients, 17.3% of the isolates showed resistance to PIs, 50.0% to NRTI, 39.2% to NNRTIs, and 9.5% to INSTIs. Multiresistance was identified in 52 isolates, 40 corresponding to two-class resistance and seven to three-class resistance. Two resistance-associated-mutations significantly associated to sub-subtype A6 samples: A62VRT and G190SRT. This study establishes the conditions for a systematic annotation of sub-subtype A6 to normalise epidemiological studies. Accurate knowledge on South Russian epidemiology will allow for the development of efficient regional frameworks for HIV-1 infection management.

scholarly journals SOCIO-CULTURAL CHARACTERISTICS OF THE POPULATION IN THE REGIONS OF NORTHWESTERN FEDERAL DISTRICT: GENERAL AND SPECIAL

2019 ◽  
Vol 3 (3) ◽  
pp. 306-316
Author(s):  
M.A. Gruzdeva ◽  
O.N. Kalachikova
Keyword(s):  
Comparative Analysis ◽  
Research Method ◽  
Federal District ◽  
Cultural Characteristics ◽  
Distinctive Features ◽  
Territorial Identity ◽  
The Republic ◽  
And Migration ◽  
Opinion Polls ◽  
Empirical Database

The article is devoted to the study of socio-cultural characteristics of the population in several regions of the Northwestern Federal District: the Vologda, Murmansk, Kaliningrad, Novgorod regions and the Republic of Karelia. The unevenness and dynamics of the development of socio-cultural subsystems of these regions are considered based on official statistics using the author's methodology. The socio-cultural characteristics of the population, in particular, the territorial identity, attitude to the place of residence, confidence in the future, migration attitudes, value field and basic interests are analyzed using the current empirical database of opinion polls, conducted in 2016 and 2017. Comparative analysis, which allowed identifying similar and distinctive features of the population in different regions, was used as a research method. The features of the Kaliningrad and Murmansk regions and the Republic of Karelia, which are conditioned by their border position, became especially evident. The findings of the general and distinctive features of socio-cultural characteristics of the population in the studied regions can contribute to improving the effectiveness of socio-economic and migration policies in the development of measures aimed at preserving and enhancing human capital.

scholarly journals Epizootic situation with bovine leukemia in the Central Federal District of the Russian Federation in 2012–2016

2020 ◽  
Vol 27 ◽  
pp. 00097
Author(s):  
Alexey Gulyukin ◽  
Vladimir Kuzmin ◽  
Leonid Fogel ◽  
Andrey Tsyganov
Keyword(s):  
Comparative Analysis ◽  
Russian Federation ◽  
Prevention And Control ◽  
Federal District ◽  
Viral Disease ◽  
Evidence Based ◽  
Central Federal District ◽  
The World ◽  
The Russian Federation ◽  
And Control

Leukemia is a chronic infectious viral disease of a tumor nature. The disease is widespread in different countries of the world and is relevant for most regions of the Russian Federation. The purpose of the work is to study the epizootic situation of leukemia in cattle in livestock farms of the Central Federal District of the Russian Federation. A complex epizootological method and evidence-based epizootology methods were used in the work. Objects of research are dysfunctional points, sick cattle. The paper presents a comparative analysis of the epizootic situation for the period 2012–2016. In the analyzed period, a total of 470 dysfunctional points for leukemia were identified, which amounted to 29.59 % of the total number of dysfunctional points in the Russian Federation and 62908 animals with leukemia were registered, which amounted to 36.90 % of the total number of diseased animals in Russia. Despite the decrease in the number of cattle infected with leukemia in five subjects, and the absence of animals that died from leukemia in all 18 subjects of the Central Federal District of the Russian Federation during 2012–2016, the epizootic situation of leukemia in the whole region remains quite tense, which is explained by the failure to comply with the basic requirements of the state veterinary service regarding sanitary anti-leukemia measures, according to the “Rules for the Prevention and Control of Leukemia of Large R gatogo cattle “ (1999.).

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