scholarly journals Optical coherence tomography of pseudophakic eyes after primary posterior capsulorhexis in pseudoexfoliation syndrome

2021 ◽  
Vol 13 (3) ◽  
pp. 13-19
Author(s):  
Elena V. Egorova ◽  
Veronika V. Dulidova ◽  
Valery V. Chernykh
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Pseudoexfoliation Syndrome ◽  
Control Group ◽  
Secondary Cataract ◽  
Primary Posterior Capsulorhexis ◽  
Nd:Yag Laser Capsulotomy ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant

Purpose to study vitreolenticular interface (VLI) and central retinal thickness after primary posterior capsulorhexis (PPC) in pseudoexfoliation syndrome (PEX). Material and methods. We conducted a dynamic OCT-evaluation of the macular morphology (47 cases) and of the VLI (39 cases) in patients with PEX in early and long term period after uncomplicated cataract surgery with PPC. In the long term period a comparative OCT-evaluation of the macula was performed in 129 patients with PEX (159 eyes) in different groups: after phacoemulsification with and without PPC, after Nd:YAG laser capsulotomy for secondary cataract, and in the control group of non-operated eyes. Results. The OCT-evaluation made it possible to visualize two significant features of VLI after PPC intact anterior hyaloid and restoration of the capsule barrier. It took 38 days for full adhesion. Secondary cataract in the PPC area was detected in one case in the long-term period. Dynamic OCT-evaluation of the macula in the main group revealed a statistically unreliable increase in the macular thickness (3.4%) in post-op period at 13 months with subsequent regression. Such changes were within the limits of physiological norm. In the remote period, comparative OCT-evaluation of the macula in different groups did not reveal statistically significant differences with the control group. Conclusion. OCT-evaluation at different post-op terms revealed the formation of stable vitreolenticular relationships and absence of clinically significant macular edema. Secondary cataract in the PPC area was detected only in one case.

Repeatability of Retinal Macular Thickness Measurements in Patients with Clinically Significant Macular Edema Using Two Different Scanning Protocols of Spectralis Optical Coherence Tomography

2015 ◽  
Vol 234 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Tito Fiore ◽  
Marco Lupidi ◽  
Sofia Androudi ◽  
Fabrizio Giansanti ◽  
Daniela Fruttini ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Retinal Thickness ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Significant Difference ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant ◽  
Thickness Measurements

Objective: To determine the repeatability of Spectralis optical coherence tomography (OCT) retinal thickness measurements in diabetic patients with clinically significant macular edema (CSME) using two different scanning protocols. Methods: Seventy-one eyes of 71 diabetic patients with CSME were included in the study. Coefficients of repeatability and intrasession variation coefficients were tested with 20 × 15 degree raster scans consisting of 19 or 37 high-resolution line scans (15 or 8 frames per scan, respectively) that were repeated 2 times by 1 experienced examiner. The first scan was set as the reference scan; the second scan was the follow-up scan and was performed with the use of the follow-up mode. Results: The mean and standard deviation for the central foveal subfield (CSF) using the first scanning method was 404 ± 88 μm, while it was 399 ± 86 μm using the second protocol, which was not statistically significantly different (p = 0.35, paired test). Particularly examining the CSF, the coefficient of repeatability was 1.48 (6.00 µm) and 1.49 (5.95 µm) for the 19- and the 37-B-scan acquisition, respectively, showing a nonstatistically significant difference (p < 0.001). Conclusions: Retinal thickness measurements in diabetic patients with CSME are repeatable using both scanning protocols (19 or 37 B-scans) with Spectralis OCT. The repeatability of the retinal thickness measurement does not improve by increasing the number of B-scans from 19 to 37.

Repeatability of Retinal Macular Thickness Measurements in Healthy Subjects and Diabetic Patients with Clinically Significant Macular Edema: Evaluation of the Follow-Up System of Spectralis Optical Coherence Tomography

2015 ◽  
Vol 233 (3-4) ◽  
pp. 186-191 ◽  
Author(s):  
Tito Fiore ◽  
Marco Lupidi ◽  
Sofia Androudi ◽  
Fabrizio Giansanti ◽  
Daniela Fruttini ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Healthy Subjects ◽  
Control Group ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant ◽  
Thickness Measurements

Background: It was the aim of this study to compare the repeatability of Spectralis optical coherence tomography (OCT) retinal thickness measurements in healthy subjects and diabetic patients with clinically significant macular edema (CSME) with or without the use of the follow-up system. Methods: Thirty-eight eyes of 38 healthy subjects (control group) and 68 eyes of 68 diabetic patients with CSME were included in the study. The coefficient of repeatability (CR) and intrasession coefficients of variation were tested with 20 × 15 degree raster scans consisting of 19 high-resolution line scans (15 frames per scan) that were repeated 3 times by 1 experienced examiner. The first scan was set as the reference scan, whereas the second and third scans were the follow-up scans and were performed with and without the use of the follow-up mode, respectively. Results: The means and standard deviations for the central foveal subfield (CSF) in healthy subjects and diabetic patients were 289 ± 21 and 402 ± 105 μm, respectively. Particularly in diabetic patients, examining the CSF, CR was 2.67% (10.73 µm) and 6.73% (27.01 µm) with and without using the follow-up mode, respectively, and the difference was statistically significant (p < 0.05). Conclusion: These results support the hypothesis that the follow-up system improves the repeatability either in healthy subjects or in diabetic patients with poor fixation. The wider improvement in repeatability in diabetic patients in the follow-up system group compared to the no follow-up system group are probably related to poor patient fixation or eye movement in patients with CSME.

scholarly journals The optical coherence tomography angiography manifestation of strabismus amblyopia with eccentric fixation

2020 ◽  
Author(s):  
Hongxing Ren ◽  
Jing Cheng ◽  
Aijiao Qin ◽  
Minghua Shi
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Thickness ◽  
Control Group ◽  
Optical Coherence ◽  
Deviation Angle ◽  
Vascular Plexus ◽  
Eccentric Fixation ◽  
Fixation Distance ◽  
Experimental Group

Abstract BackgroundTo explore the application value of optical coherence tomography angiography (OCTA) in patients with strabismus amblyopia accompanied by eccentric fixation.MethodsThe following data were collected from patients with strabismus amblyopia accompanied by eccentric fixation: best corrected visual acuity (BCVA); spherical equivalent (SE) and deviation angle; eccentric fixation distance using OCTA system software tools, with µm as the unit of measurement of the distance between the retinal fixed point and the macular fovea; macular fovea vessel length density (VLD); perfusion density (PD); foveal avascular zone (FAZ) area; and perimeter and circularity of the superficial retinal vascular plexus. The entry criteria were as follows: OCTA scanning quality and signal strength of 8 or above (range 0 to 10).ResultsData from a total of 34 patients were collected: 17 patients with strabismus amblyopia with eccentric fixation were included in the experimental group, and 17 patients without strabismus with central fixation were included in the control group. The average deviation angle of the experimental group was 26.71 ± 25.88 prism dioptres (PD), the amblyopic eye BCVA was 0.24 ± 0.22, the SE was 4.35 ± 2.98 D, the stereoscopic median was 800", the eccentric fixation distance was 632.18 ± 310.62 µm, the macular fovea retinal thickness was 207.82 ± 17.79 µm, the VLD of the superficial retinal vascular plexus was 7.31 ± 3.84 mm− 1, the PD was 0.16 ± 0.08, the FAZ area was 0.28 ± 0.17 mm2, the FAZ perimeter was 2.05 ± 0.56 mm, and the FAZ circularity was 0.67 ± 0.06. These results showed statistically significant differences in the SE and BCVA compared with the lateral eye and the control group, but there were no statistically significant differences in the macular fovea retinal thickness, VLD, PD, or FAZ. The eccentric fixation of amblyopic eyes was directly related to the deviation angle, and the regression formula was as follows: the eccentric fixation distance of amblyopic eyes = 8.319 × the deviation angle + 410.002 (F = 13.878, P = 0.002 < 0.01).ConclusionThe eccentric fixation distance of strabismus amblyopia with eccentric fixation is related to the deviation angle; the greater the deviation angle is, the greater the distance of eccentric fixation.Trial registrationChinese Clinical Trial Registry, ChiCTR1900022830. Registered 27 April 2019, http://www.chictr.org.cn/

scholarly journals Comparison of inner macular thickness and superficial macular capillary vessel density acquired using classic and high-definition optical coherence tomography angiography scans

2021 ◽  
Vol 3 (1) ◽  
pp. 43-54
Author(s):  
Gabor Hollo
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Open Angle Glaucoma ◽  
Imaging Study ◽  
Vessel Density ◽  
Optical Coherence ◽  
High Definition ◽  
Normal Value ◽  
Image Area ◽  
Clinically Significant

Background: In ophthalmology, thickness and vessel density (VD) measurements for the 6 x 6 mm inner macular retinal area have received increasing attention in glaucomatous progression research. For this area, the Angiovue optical coherence tomography system introduced a 304 x 304 A/B scans function (classic Angio Retina scan) in 2014, and a 400 x 400 A/B scans function (high-definition [HD] Angio Retina scan) in 2017. These scan types cannot be used in combination for the software provided for progression analysis.Purpose: Since losing data for 3 years may negatively influence progression analysis, we investigated whether clinically significant differences exist between consecutive measurements acquired with these scan types on the same eyes.Methods: As a part of our noninterventional prospective glaucoma imaging study, primary-open-angle glaucoma patients (POAG group), and ocular hypertensive and healthy control participants (structurally undamaged group) were imagedusing both the classic and the HD Angio Retina scans, respectively, without changing the patients’ position. High-quality images were obtained on 12 POAG eyes of 12 consecutive POAG patients, and 10 healthy and ocular hypertensive eyes of 10 consecutive participants before the data collection had to be suspended due to the new coronavirus epidemic.Results: For Early Treatment Diabetic Retinopathy Study image area, the mean difference (classic minus HD value) was 0.02 ± 0.37 μm for inner retinal thickness (P = 0.869) and 0.33 ± 1.33 % (P = 0.452) for superficial capillary VD in the structurally normal group (between-methods difference: ≤ 0.8% of the respective normal value). In the POAG group, the corresponding figures were -0.07 ± 1.22 μm for inner retinal thickness (P = 0.854; between-methods difference: 0.6% of the normal value) and 1.12 ± 2.58 % for superficial capillary VD (P = 0.158; classic scan value minus HD scan value: 1.12 ± 2.58 %; 2.3% of the normal value).Conclusion: Our results suggest that combined use of thickness and VD values for structurally normal eyes and thickness values for POAG eyes derived from classic and HD scans, respectively, for progression analysis can be reasonable since the differences between the corresponding values are small. However, combining the corresponding VD parameters for POAG eyes is useful only when the follow-up time before the scan type change is long enough to counterbalance the effect of the change on the result.  

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