scholarly journals Initial positive first-hand experience of acute keratoconus treatment using platelet-rich serums

2020 ◽  
Vol 13 (4) ◽  
pp. 67-72
Author(s):  
Kirill V. Khripun ◽  
Yulia V. Kobinets ◽  
Elizaveta S. Rozhdestvenskaya
Keyword(s):  
Optical Coherence Tomography ◽  
Side Effects ◽  
Clinical Case ◽  
Platelet Rich Plasma ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Optical Coherence ◽  
Autologous Plasma ◽  
Tomography Data ◽  
Acute Keratoconus

Presentation of a clinical case of acute keratoconus treatment by the intracameral platelet-rich plasma administration. Clinical and morphological improvement was registered from the first postoperative day, corneal edema and bullous changes completely resolved during 3 weeks. No side effects were observed. The outcome is confirmed by anterior segment optical coherence tomography data Intracameral platelet-rich autologous plasma administration is a safe and effective method of acute keratoconus treatment.

Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography

2020 ◽  
pp. 112067212094479
Author(s):  
Christian M Wertheimer ◽  
Carolin Elhardt ◽  
Andreas Wartak ◽  
Nikolaus Luft ◽  
Stefan Kassumeh ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Density ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Diagnostic Tools ◽  
Control Group ◽  
Distilled Water ◽  
Optical Coherence ◽  
Corneal Surgery ◽  
Disease Characteristics

Purpose: In this study, we propose a method to grade corneal stromal opacity using optical density measurements by anterior segment optical coherence tomography (AS-OCT) and validate the approach in Fuchs endothelial corneal dystrophy (FECD). Methods: A retrospective analysis of human corneal OCT scans was performed on 48 eyes of 32 patients with FECD and 33 control eyes of 21 patients using the Carl Zeiss Cirrus HD-OCT 5000. In addition, corneal edema in fresh rabbit cadaver eyes was artificially induced by distilled water and imaged with the Thorlabs TELESTO-II spectral domain OCT at different time points during saturation. The increase of opacity due to corneal edema was proposed to directly correlate with enhanced reflectivity sites in the OCT images, corresponding to higher optical density. The increase was determined as the image area above a statistically established gray-scale value using ImageJ and correlated with other disease characteristics. Results: Optical densities in human corneas showed significant differences between FECD patients and the control group ( p = 0.002). The increased optical densities determined in FECD corneas correlated well with other disease characteristics such as corneal pachymetry or visual acuity. Likewise, rabbit corneas showed a time dependent increase in thickness and in corneal optical density during soaking in distilled water. Conclusion: This study presents corneal optical density by AS-OCT as an objective value for corneal changes in FECD. Complementing other diagnostic tools in FECD the assessment of corneal optical density may identify progression of FECD, gauge novel therapeutic strategies and support risk and benefit analyses for corneal surgery.

scholarly journals The Value of Anterior Segment Optical Coherence Tomography in Different Types of Corneal Infections: An Update

2021 ◽  
Vol 10 (13) ◽  
pp. 2841
Author(s):  
Ahmed A. Abdelghany ◽  
Francesco D’Oria ◽  
Jorge Alio Del Barrio ◽  
Jorge L. Alio
Keyword(s):  
Optical Coherence Tomography ◽  
Imaging Modality ◽  
Wide Spectrum ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Response To Treatment ◽  
Optical Coherence ◽  
Slit Lamp ◽  
Cross Sectional

Anterior segment optical coherence tomography (AS-OCT) is a modality that uses low-coherence interferometry to visualize and assess anterior segment ocular features, offering several advantages of being a sterile and noncontact modality that generates high-resolution cross-sectional images of the tissues. The qualitative and quantitative information provided by AS-OCT may be extremely useful for the clinician in the assessment of a wide spectrum of corneal infections, guiding in the management and follow-up of these patients. In clinical practice, infections are routinely evaluated with slit-lamp biomicroscopy, an examination and imaging modality that is limited by the physical characteristics of light. As a consequence, the depth of pathology and the eventually associated corneal edema cannot be accurately measured with the slit-lamp. Therefore, it represents a limit for the clinician, as in vivo information about corneal diseases and the response to treatment is limited. Resolution of corneal infection is characterized by an early reduction in corneal edema, followed by a later reduction in infiltration: both parameters can be routinely measured with standardized serial images by AS-OCT.

scholarly journals Successful Treatment of Post-Phacoemulsification Descemet’s Membrane Detachment Assessed by Anterior Segment Optical Coherence Tomography: A Case Report

2021 ◽  
pp. 611-615
Author(s):  
Ayaka Doi ◽  
Tadamichi Akagi ◽  
Akitaka Tsujikawa
Keyword(s):  
Optical Coherence Tomography ◽  
Sulfur Hexafluoride ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Optical Coherence ◽  
Descemet’S Membrane Detachment ◽  
Intracameral Injection ◽  
Descemet's Membrane ◽  
Descemet’S Membrane ◽  
The Right

Descemet’s membrane detachment (DMD) is a rare but serious complication of phacoemulsification surgery. A small DMD may resolve spontaneously, but extensive DMD often requires intracameral injection of air, nonexpansile gases, or expansile gases. A 92-year-old man who underwent phacoemulsification and aspiration with intraocular lens placement in the right eye had significantly reduced visual acuity, with a hazy cornea after surgery. Anterior segment optical coherence tomography (AS-OCT) examination revealed extensive DMD throughout the cornea. He was treated with intracameral injection of 20% sulfur hexafluoride. As a result, the Descemet membrane was successfully reattached, and the corneal edema resolved. AS-OCT was helpful in confirming the presence and extent of DMD, provided useful information to determine the appropriate treatment, and was useful for monitoring DMD.

Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

2018 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Joshua S Agranat ◽  
Yoshihiro Yonekawa
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Incidental Finding ◽  
Pigment Epithelium ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
Optical Coherence ◽  
Visual Axis ◽  
Associated Malignancy ◽  
Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

Evaluation of Intraocular Lens Tilt With Anterior Segment Optical Coherence Tomography

2011 ◽  
Vol 151 (3) ◽  
pp. 406-412.e2 ◽  
Author(s):  
Dhivya Ashok Kumar ◽  
Amar Agarwal ◽  
Gaurav Prakash ◽  
Soosan Jacob ◽  
Yoga Saravanan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Lens ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Intraocular Lens Tilt
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