scholarly journals Corneal collagen cross-linking in mixed etiology keratitis treatment: a case of successful use

2021 ◽  
Vol 13 (3) ◽  
pp. 87-96
Author(s):  
Kirill V. Khripun ◽  
Yulia V. Kobinets ◽  
Pavel A. Danilov ◽  
Elizaveta S. Rozhdestvenskaya ◽  
Yulduz Sh. Nizametdinova
Keyword(s):  
Allergic Reaction ◽  
Effective Treatment ◽  
Clinical Case ◽  
Acanthamoeba Keratitis ◽  
Cross Linking ◽  
High Fluence ◽  
Corneal Inflammation ◽  
Long Time ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Acanthamoeba keratitis with bacterial, fungal superinfection or without it leads to development of an aggressive and long-standing corneal inflammation; up to now, the efficacy of its treatment stays doubtful and demands further investigation. For a long time, there were discussions on the possibility and expediency of corneal collagen cross-linking (PACK-CXL photo activated chromophore for keratitis) in patients with bacterial, fungal and Acanthamoeba keratitis. This article presents a clinical case of effective treatment of mixed etiology keratitis by multiple high fluence accelerated PACK-CXL in a patient with severe local toxico-allergic reaction.

Corneal Collagen Cross-Linking for the Treatment of Acanthamoeba Keratitis

Cornea ◽  
2013 ◽  
Vol 32 (10) ◽  
pp. e189 ◽  
Author(s):  
Olivier Richoz ◽  
Zisis Gatzioufas ◽  
Farhad Hafezi
Keyword(s):  
Acanthamoeba Keratitis ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Corneal Collagen

High Fluence Iontophoretic Corneal Collagen Cross-linking: In Vivo OCT Imaging of Riboflavin Penetration

2013 ◽  
Vol 29 (6) ◽  
pp. 376-377 ◽  
Author(s):  
Paolo Vinciguerra ◽  
Miguel Rechichi ◽  
Pietro Rosetta ◽  
Mario R. Romano ◽  
Leonardo Mastropasqua ◽  
...  
Keyword(s):  
Cross Linking ◽  
High Fluence ◽  
Oct Imaging ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Long term results of accelerated corneal collagen cross-linking in pediatric keratoconus

2021 ◽  
pp. 112067212110183
Author(s):  
Yasin Cinar ◽  
Cagla Cilem Han ◽  
Alparslan Sahin ◽  
Zeba A Syed
Keyword(s):  
Visual Acuity ◽  
Corneal Thickness ◽  
University Hospital ◽  
Long Term Results ◽  
Cross Linking ◽  
Distance Visual Acuity ◽  
The Mean ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Purpose: To evaluate the long term visual, refractive, and corneal tomographic outcomes of epithelium-off accelerated corneal collagen cross-linking (ACXL) in the management of pediatric keratoconus (KC). Methods: This retrospective study included patients under 18 years old with progressive KC who underwent ACXL between 2012 and 2019 at Dicle University Hospital. Complete ophthalmic examination was performed including uncorrected distance visual acuity (UDVA), best spectacle-corrected distance visual acuity (CDVA), manifest refraction, and corneal tomography. Evaluations were performed preoperatively and at 6 months intervals postoperatively. Results: Forty-nine eyes of 49 patients were included in the study. The mean age of patients at the time of ACXL was 14.2 ± 1.8 (range: 9.5–17.3) years. Mean follow up was 4.61 ± 1.90 (range: 2.0–8.1) years. The mean LogMAR UDVA improved from 0.94 ± 0.41 to 0.81 ± 0.43, 0.69 ± 0.41, and 0.67 ± 0.33 after 1, 3, and 5 years respectively ( p = 0.001). The mean LogMAR CDVA improved from 0.58 ± 0.36 to 0.46 ± 0.31, 0.34 ± 0.23, and 0.39 ± 0.27 after 1, 3, and 5 years respectively ( p = 0.015). The mean refractive cylinder improved significantly from 6.01 ± 2.07 diopters (D) to 5.46 ± 1.87, 5.38 ± 2.18, and 5.02 ± 2.31 D after 1, 3, and 5 years respectively ( p = 0.005). As compared to preoperative values, steep keratometry and maximum keratometry were not significantly different ( p = 0.805 and 0.448, respectively) following ACXL, while flat keratometry significantly improved after ACXL ( p = 0.012). Although central corneal thicknesses decreased significantly ( p = 0.029), the decrease in thinnest corneal thickness was not statistically significant ( p = 0.205). Conclusion: Epithelium-off ACXL seems to be effective for halting KC progression with long term clinical benefits in pediatric patients.

Corneal Collagen Cross-Linking in Young Patients for Progressive Keratoconus

Cornea ◽  
2020 ◽  
Vol 39 (2) ◽  
pp. 186-191
Author(s):  
Paulo Rodolfo Tagliari Barbisan ◽  
Roberto Damian Pacheco Pinto ◽  
Camillo Carneiro Gusmão ◽  
Rosane Silvestre de Castro ◽  
Carlos Eduardo Leite Arieta
Keyword(s):  
Young Patients ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Corneal Collagen
Sign in / Sign up

Export Citation Format

Share Document