Prospective study of serum homocysteine and risk of ischemic stroke among patients with preexisting coronary heart disease (Stroke. — 2003. —Mar. — 34(3). — P. 632—636: англ.)

2003 ◽  
Vol XXXV (1-2) ◽  
pp. 78-79
Author(s):  
D. Tanne ◽  
M. Haim ◽  
U. Goldbourt ◽  
V. Boyko ◽  
R. Doolman ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Prospective Study ◽  
Blood Serum ◽  
Vascular Endothelium ◽  
Serum Homocysteine ◽  
Blood Clots

According to modern data, homocysteine damages the vascular endothelium, contributing to the formation of lipid plaques and blood clots. The aim of the study was to determine the risk of ischemic stroke in persons with coronary heart disease, depending on the level of homocysteine in the blood serum.

scholarly journals Prospective Study of Serum Homocysteine and Risk of Ischemic Stroke Among Patients With Preexisting Coronary Heart Disease

Stroke ◽  
2003 ◽  
Vol 34 (3) ◽  
pp. 632-636 ◽  
Author(s):  
David Tanne ◽  
Moti Haim ◽  
Uri Goldbourt ◽  
Valentina Boyko ◽  
Ram Doolman ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Prospective Study ◽  
Serum Homocysteine

Possibilities for treating aspirin-i lesions of the stomach and duodenum in patients with chronic coronary heart disease

2020 ◽  
Vol 98 (3) ◽  
pp. 231-235
Author(s):  
N. Yu. Borovkova ◽  
M. V. Buyanova ◽  
T. E. Bakka ◽  
M. P. Nistratova ◽  
T. V. Vlasova ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Proton Pump Inhibitor ◽  
Blood Serum ◽  
Proton Pump ◽  
The Body ◽  
Control Group ◽  
Pge2 Level ◽  
Endogenous Prostaglandins ◽  
Chronic Coronary Heart Disease

To evaluate possibilities of aspirin-induced gastroduodenopathy treatment in the patients with chronic ischemic heart disease by means of applying the internal endogenous prostaglandins stimulant.  Material and methods. 340 patients suffering from chronic coronary heart disease and receiving a long-term acetylsalicylic acid (ASA) therapy were examined on the base of the cardiovascular care unit of The Nizhny Novgorod Regional Clinical Hospital named after N.A. Semaschko. There were evaluated frequency, nature and severity of the aspirin-induced gastroduodenopathy. The patients with coronary heart disease and aspirin-induced gastroduodenopathy were divided in two groups. In the first group of patients there was applied rebamipide therapy (in a single daily dose 300 mg) in combination with the proton pump inhibitor (PPI) — pantoprazole. In the second group there was applied only pantoprazole therapy. For the purpose of specification of AIG pathogenetic mechanisms development, all the examined chronic coronary heart disease cases were tested on the prostaglandin E2 (PGE2) level in blood serum before the therapy beginning and after the treatment. The control group was formed of chronic coronary heart disease patients showing no AIG evidence. Statistical processing of the received data was fulfilled with the program «Statistika 10.0». Results. AIG was registered in 15% out of 340 chronic coronary heart disease patients. According to the endoscopic examination erosive disease of the body and antrum prevailed among the patients. The PGE2 level in the blood serum was significantly lower (р = 0,00087) in these patients in comparison with the control group. In association with PPI and rebamipide mixed therapy, esophagogastroduodenoscopy results showed no pathological findings in gastrointestinal mucosa and statistically significant (р = 0,00067) blood serum PGE2 level growing in all the treated patients. As a result of exclusive PPI therapy there was marked positive dynamics in endoscopic view in 19 out of 25 patients and a tendency to normalization of PGE2 level in the blood serum. However, PGE2 level growing was insignificant. Conclusion. The presented research demonstrates the possibility of AIG treatment with the use of internal endogenous prostaglandins stimulant — rebamipide in complex with proton pump inhibitor PPI therapy.

Prospective Study of Hemostatic Factors and Incidence of Coronary Heart Disease

Circulation ◽  
1997 ◽  
Vol 96 (4) ◽  
pp. 1102-1108 ◽  
Author(s):  
Aaron R. Folsom ◽  
Kenneth K. Wu ◽  
Wayne D. Rosamond ◽  
A. Richey Sharrett ◽  
Lloyd E. Chambless
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Prospective Study ◽  
Hemostatic Factors

scholarly journals Prospective study of phobic anxiety and risk of coronary heart disease in men.

Circulation ◽  
1994 ◽  
Vol 89 (5) ◽  
pp. 1992-1997 ◽  
Author(s):  
I Kawachi ◽  
G A Colditz ◽  
A Ascherio ◽  
E B Rimm ◽  
E Giovannucci ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Prospective Study ◽  
Phobic Anxiety

scholarly journals The CHADS2 score predicts ischemic stroke in the absence of atrial fibrillation among subjects with coronary heart disease: Data from the Heart and Soul Study

2011 ◽  
Vol 162 (3) ◽  
pp. 555-561 ◽  
Author(s):  
Christine C. Welles ◽  
Mary A. Whooley ◽  
Beeya Na ◽  
Peter Ganz ◽  
Nelson B. Schiller ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Chads2 Score

scholarly journals Systemic chemokine levels, coronary heart disease, and ischemic stroke events: The PRIME Study

Neurology ◽  
2011 ◽  
Vol 77 (12) ◽  
pp. 1165-1173 ◽  
Author(s):  
F. Canoui-Poitrine ◽  
G. Luc ◽  
Z. Mallat ◽  
E. Machez ◽  
A. Bingham ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke
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