scholarly journals Pathological changes in the central nervous system, caused by a lumbar puncture

2020 ◽  
Vol VIII (3) ◽  
pp. 28-66
Author(s):  
V. P. Osipov

One of the most important purposes of scientific experiments performed by doctors on animals is to serve the interests of the clinic; it is a well-established fact, thanks to which modern medicine in general, and the clinic in particular, has been enriched with the greatest discoveries. Particularly important is the preliminary conduct of experiments on animals, when the clinic offers new means of treating diseases, which, for theoretical reasons, may turn out to be harmful to the human body; the use of such a means can be justified only in the case if the good results achieved by them cover its temporary harmful effect; but even under such conditions, the doctor should be aware of the unfavorable aspects of the action of the means used by him.

Author(s):  
Elias Manca

AbstractSystemic lupus erythematosus is a complex immunological disease where both environmental factors and genetic predisposition lead to the dysregulation of important immune mechanisms. Eventually, the combination of these factors leads to the production of self-reactive antibodies that can target any organ or tissue of the human body. Autoantibodies can form immune complexes responsible for both the organ damage and the most severe complications. Involvement of the central nervous system defines a subcategory of the disease, generally known with the denomination of neuropsychiatric systemic lupus erythematosus. Neuropsychiatric symptoms can range from relatively mild manifestations, such as headache, to more severe complications, such as psychosis. The evaluation of the presence of the autoantibodies in the serum of these patients is the most helpful diagnostic tool for the assessment of the disease. The scientific progresses achieved in the last decades helped researchers and physicians to discover some of autoepitopes targeted by the autoantibodies, although the majority of them have not been identified yet. Additionally, the central nervous system is full of epitopes that cannot be found elsewhere in the human body, for this reason, autoantibodies that selectively target these epitopes might be used for the differential diagnosis between patients with and without the neuropsychiatric symptoms. In this review, the most relevant data is reported with regard to mechanisms implicated in the production of autoantibodies and the most important autoantibodies found among patients with systemic lupus erythematosus with and without the neuropsychiatric manifestations.


The Analyst ◽  
2020 ◽  
Vol 145 (22) ◽  
pp. 7380-7387 ◽  
Author(s):  
Huming Yan ◽  
Fangjun Huo ◽  
Yongkang Yue ◽  
Jianbin Chao ◽  
Caixia Yin

The excellent water solubility of hydrazine (N2H4) allows it to easily invade the human body through the skin and respiratory tract, thereby damaging human organs and the central nervous system.


2021 ◽  
Author(s):  
Carl Nikolaus Homann

The nervous system is the most complex organ in the human body, and it is the most essential. However nerve cells are particularly precious as, only like muscle cells, once formed, they do not replicate. This means that neural injuries cannot easily be replaced or repaired. Vitamin D seems to play a pivotal role in protecting these vulnerable and most important structures, but exactly how and to what extend is still subject to debate. Systematically reviewing the vast body of research on the influence of Vitamin D in various neuropathological processes, we found that Vitamin D particularly plays a mitigating role in the development of chronic neurodegeneration and the measured response to acutely acquired traumatic and non-traumatic nerve cells incidents. Adequate serum levels of Vitamin D before the initiation of these processes is increasingly viewed as being neuroprotective. However, comprehensive data on using it as a treatment during the ongoing process or after the injury to neurons is completed are much more ambiguous. A recommendation for testing and supplementation of insufficiencies seems to be well-founded.


2020 ◽  
Vol 24 (3) ◽  
pp. 26-36
Author(s):  
A. S. Vinokurov ◽  
M. V. Nikiforova ◽  
A. A. Oganesyan ◽  
O. O. Vinokurova ◽  
A. L. Yudin ◽  
...  

Item. To evaluate the features of CT imaging of the liver and the possible causes of pathological changes in COVID-19.Materials and methods. An analysis of the literature and our own data on the features of CT imaging of the liver in combination with biochemical analyzes in patients with COVID-19 was performed. The main possible causes of changes in the liver, as well as symptoms with CT, are examined.Results. The main target of the new SARS-CoV-2 coronavirus is the respiratory system. But among patients with COVID-19, along with damage to the central nervous system, myocardium, and intestines, cases of liver damage or dysfunction have been reported. This is expressed in an increase in biochemical markers of liver damage, as well as in a diffuse decrease in its density during CT, which is usually observed in the acute stage of the disease.


2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Rahmita Wirza ◽  
Shah Nazir ◽  
Habib Ullah Khan ◽  
Iván García-Magariño ◽  
Rohul Amin

The medical system is facing the transformations with augmentation in the use of medical information systems, electronic records, smart, wearable devices, and handheld. The central nervous system function is to control the activities of the mind and the human body. Modern speedy development in medical and computational growth in the field of the central nervous system enables practitioners and researchers to extract and visualize insight from these systems. The function of augmented reality is to incorporate virtual and real objects, interactively running in a real-time and real environment. The role of augmented reality in the central nervous system becomes a thought-provoking task. Gesture interaction approach-based augmented reality in the central nervous system has enormous impending for reducing the care cost, quality refining of care, and waste and error reducing. To make this process smooth, it would be effective to present a comprehensive study report of the available state-of-the-art-work for enabling doctors and practitioners to easily use it in the decision making process. This comprehensive study will finally summarise the outputs of the published materials associate to gesture interaction-based augmented reality approach in the central nervous system. This research uses the protocol of systematic literature which systematically collects, analyses, and derives facts from the collected papers. The data collected range from the published materials for 10 years. 78 papers were selected and included papers based on the predefined inclusion, exclusion, and quality criteria. The study supports to identify the studies related to augmented reality in the nervous system, application of augmented reality in the nervous system, technique of augmented reality in the nervous system, and the gesture interaction approaches in the nervous system. The derivations from the studies show that there is certain amount of rise-up in yearly wise articles, and numerous studies exist, related to augmented reality and gestures interaction approaches to different systems of the human body, specifically to the nervous system. This research organises and summarises the existing associated work, which is in the form of published materials, and are related to augmented reality. This research will help the practitioners and researchers to sight most of the existing studies subjected to augmented reality-based gestures interaction approaches for the nervous system and then can eventually be followed as support in future for complex anatomy learning.


2019 ◽  
Vol 4 (2) ◽  
pp. 21-26
Author(s):  
Simerzin VV ◽  
Fatenkov OV ◽  
Panisheva YaA ◽  
Galkina MA ◽  
Gagloev AV

The review article reflects the specific features of involutive cognitive functions in elderly people. Furthermore the basis of these changes is the natural physiological process of morphofunctional remodeling of the human body in general and of the central nervous system in particular. As a result, the elderly and senium people have cognitive decline, and in the presence of provoking medical and social factors and comorbid diseases they may have transient cognitive dysfunction.


The human neurological system has an effective impact by meditation, mantra therapy, music therapy, Raga therapy and Vedic chanting. To detect this effect on Human Neurological system, it is necessary to analyse the signal energy from the appropriate sources which are generating audible frequencies. By these generated frequencies, the Central Nervous System of brain will be relaxed. This process follows, Calculation of Special acoustic signals originated from Vedic Chanting, classification of these signals with respect to the levels of amplitude and frequency, analysing the impact of these signal energies on the neurotransmission. It also focuses and involves limbic and para-limbic regions of neuro-transmission. This paper presents impact of vedic chanting signal positive vibrations on human body brain and nervous System


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