scholarly journals A. P. Bazilevsky. On the descending systems of the cerebellum in the spinal cord by the method of fresh rebirths (Marchi). — Diss. SPb. 1896

2020 ◽  
Vol V (2) ◽  
pp. 178-179

For the purpose of repetition of Biedl's experiments, the author cut the hind cerebellar peduncle in dogs and studied the descending degeneration in the spinal cord. Based on the results of his research, the author comes to the following conclusions.

Neuroscience ◽  
2012 ◽  
Vol 227 ◽  
pp. 67-79 ◽  
Author(s):  
A. Du Beau ◽  
S. Shakya Shrestha ◽  
B.A. Bannatyne ◽  
S.M. Jalicy ◽  
S. Linnen ◽  
...  

Author(s):  
Calvin C. Smith ◽  
Robert M. Brownstone

AbstractAltricial mammals are born with immature nervous systems comprised of circuits that do not yet have the neuronal properties and connectivity required to produce future behaviours. During the critical period of post-natal development, neuronal properties are tuned to participate in functional circuits. In rodents, cervical motoneurons are born prior to lumbar motoneurons, and spinal cord development follows a sequential rostro-caudal sequence. Here we asked whether birth order is reflected in the post-natal development of electrophysiological properties. We show that motoneurons of both segments have similar properties at birth and follow the same developmental profile, with maximal firing increasing and excitability decreasing into the 3rd post-natal week. However, these maturative processes occur in cervical prior to lumbar motoneurons, correlating to the timing of arrival of descending systems. These results suggest that motoneuron properties do not mature by cell autonomous mechanisms alone, but rather depend on developing descending and spinal circuits.


2020 ◽  
Vol VII (3) ◽  
pp. 29-43
Author(s):  
A. E. Yanishevsky

Among the still very few elucidated questions about the course of fibers in the spinal cord is the question of the descending systems in the posterior columns. Until recently, a view was adopted that the posterior columns of the spinal cord pass through the systems of fibers, going in the direction of the brain. This view was mainly based on the fact that in case of spinal cord disorders, the Wallerian regeneration of the fibers was higher than the damage.


1980 ◽  
Vol 8 (3) ◽  
pp. 248-256 ◽  
Author(s):  
Peter R. Wilson ◽  
Tony L. Yaksh

Physiological events involved in nociception and pain perception are examined. Substance P could be a primary afferent transmitter of certain nociceptive information. Transmission of this information can be modulated within the spinal cord by intrinsic and descending mechanisms. The intrinsic mechanism involves inhibitory opiate effects within substantia gelatinosa. Centres for descending systems are located in medulla and periaqueductal gray matter. They are activated by exogenous narcotic agonists, and by regional connections. Descending inhibitory pathways are serotonergic and noradrenergic. GABA and glycine are also possibly involved in antinociception. Narcotics have been shown to produce analgesia when administered to the intrathecal or epidural spaces of humans. These routes are still experimental. The place of clinical modification of transmitter system is discussed, but no conclusions or recommendations can be made at this early stage.


1970 ◽  
Vol 44 (2) ◽  
pp. 404 ◽  
Author(s):  
Karin E. Olson ◽  
Charles D. Barnes

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