NON-MOTOR SYMPTOMS AND QUALITY OF LIFE IN PATIENTS WITH ESSENTIAL TREMOR, PARKINSONS DISEASE AND THE COMBINATION OF ESSENTIAL TREMOR AND PARKINSONS DISEASE

2018 ◽  
Vol 18 (2) ◽  
pp. 63-71 ◽  
Author(s):  
A V Kudrevatykh ◽  
M D Didur ◽  
TV V Sergeev ◽  
D S Bug ◽  
I V Miliukhina
Keyword(s):  
Quality Of Life ◽  
Essential Tremor ◽  
Depressive Disorders ◽  
Clinical Manifestations ◽  
Motor Symptoms ◽  
Parkinsons Disease ◽  
Early Stages ◽  
Wide Range ◽  
Non Motor Symptoms

Aim of the study: to assess non-motor symptoms and quality of life in patients with essential tremor (ET), different stages of Parkinson’s Disease (PD) and combination of ET and PD (ET-PD). Materials and methods of the research: We examined 82 patients with ET, 20 patients with ET-PD, 283 patients with PD, and 72 neurologically healthy volunteers. The neuropsychological status, intensity of motor symptoms, the grade of vegetative dysfunction and dyssomnia, and quality of life of patients were assessed. Results: Patients with ET showed wide range of nonmotor symptoms. The severity of cognitive impairment in group of patients with ET corresponded with the same severity of patients with early stages of PD. It is interesting that patients with ET showed more severe depression than patients with early stages of PD. The maximum severity of anxiety-depressive disorders was observed in patients with the combination of ET-PD. Conclusion: In spite of the fact that it is usual to consider the ET as a monosymptomatic benign disease, we have found significant non-motor disorders in this group of patients and a significant violation of the quality of life. The results of the study also give evidence that patients with ET-PD represent a special group of patients, characterized by special, both motor and non-motor symptoms. The data we obtained made it possible to form a deeper understanding of the generality of the clinical manifestations of ET, PD and ET-PD, which will make it possible to improve the quality of management of patients with these nosologies in clinical practice.

scholarly journals Non-Motor Symptoms of Essential Tremor Are Independent of Tremor Severity and Have an Impact on Quality of Life

2016 ◽  
Vol 6 (0) ◽  
pp. 361 ◽  
Author(s):  
Thomas Musacchio ◽  
Veronika Purrer ◽  
Aikaterini Papagianni ◽  
Anna Fleischer ◽  
Daniel Mackenrodt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Essential Tremor ◽  
Motor Symptoms ◽  
Non Motor Symptoms

Non-Motor Symptoms of Amyotrophic Lateral Sclerosis: A Multi-Faceted Disorder

2021 ◽  
pp. 1-15
Author(s):  
Yuval Nash ◽  
Michal Sitty
Keyword(s):  
Quality Of Life ◽  
Amyotrophic Lateral Sclerosis ◽  
Motor Symptoms ◽  
Motor Pathways ◽  
Progressive Degeneration ◽  
Wide Range ◽  
Growing Body ◽  
Non Motor Symptoms ◽  
Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive degeneration of motor pathways. A growing body of evidence from recent years suggests that ALS results in a wide range of non-motor symptoms as well, which can have a significant impact on patients’ quality of life. These symptoms could also, in turn, provide useful information as biomarkers for disease progression, and can shed insight on ALS mechanisms. Here we aim to review a wide range of non-motor symptoms of ALS, with emphasis on their importance to research and clinical treatment of patients.

scholarly journals Clinical Profile of Non-Motor Symptoms in Patients with Essential Tremor: Impact on Quality of Life and Age-Related Differences

2019 ◽  
Vol 9 (0) ◽  
Author(s):  
Ali S. Shalash ◽  
Hadeer Mohamed ◽  
Alia H. Mansour ◽  
Ahmed Elkady ◽  
Hanan Elrassas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Essential Tremor ◽  
Clinical Profile ◽  
Motor Symptoms ◽  
Age Related ◽  
Non Motor Symptoms

scholarly journals Gastrointestinal Symptoms in Parkinson Disease: Clinical Aspects and Management

2011 ◽  
Vol 38 (4) ◽  
pp. 557-564 ◽  
Author(s):  
D. Salat-Foix ◽  
C. N. Andrews ◽  
J. Meddings ◽  
O. Suchowersky
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Clinical Manifestations ◽  
Gastrointestinal Symptoms ◽  
Clinical Aspects ◽  
Motor Symptoms ◽  
Comprehensive Management ◽  
Gastrointestinal Side Effects ◽  
Non Motor Symptoms

Although it is now generally recognized that the clinical spectrum of Parkinson disease (PD) is broader than its defining motor aspects, its various non-motor symptoms are often not routinely assessed in the clinical setting. As most of these symptoms are amenable to treatment, improved recognition would lead to more comprehensive management of the disease, and ultimately improve the quality of life for PD patients. In an attempt to increase the general awareness of physicians caring for these patients, this article focuses on the clinical manifestations and treatment of the gastrointestinal symptoms most commonly experienced by PD patients, as well as on the gastrointestinal side effects of antiparkinsonian treatments.

scholarly journals The Parkinson’s Real-World Impact Assessment (PRISM) Study: A European Survey of the Burden of Parkinson’s Disease in Patients and their Carers

2021 ◽  
pp. 1-15
Author(s):  
Eduardo Tolosa ◽  
Georg Ebersbach ◽  
Joaquim J. Ferreira ◽  
Olivier Rascol ◽  
Angelo Antonini ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impact Assessment ◽  
Real World ◽  
European Countries ◽  
Life Questionnaire ◽  
Motor Symptoms ◽  
Non Motor Symptoms

Background: A greater understanding of the everyday experiences of people with Parkinson’s disease (PD) and their carers may help improve clinical practice. Objective: The Parkinson’s Real-world Impact assesSMent (PRISM) study evaluated medication use, health-related quality of life (HRQoL) and the use of healthcare resources by people with PD and their carers. Methods: PRISM is an observational cross-sectional study, in which people with PD and their carers completed an online survey using structured questionnaires, including the Parkinson’s Disease Quality of Life Questionnaire (PDQ-39), Non-Motor Symptoms Questionnaire (NMSQuest) and Zarit Burden Interview (ZBI). Results: Data were collected from 861 people with PD (mean age, 65.0 years; mean disease duration, 7.7 years) and 256 carers from six European countries. People with PD reported a large number of different co-morbidities, non-motor symptoms (mean NMSQuest score, 12.8), and impaired HRQoL (median PDQ-39 summary score, 29.1). Forty-five percent of people with PD reported at least one impulse control behaviour. Treatment patterns varied considerably between different European countries. Levodopa was taken in the last 12 months by 85.9% of participants, and as monotherapy by 21.8% . Carers, who were mostly female (64.8%) and the partner/spouse of the person with PD (82.1%), reported mild to moderate burden (mean ZBI total score, 26.6). Conclusions: The PRISM study sheds light on the lives of people with PD and those who care for them, re-emphasising the many challenges they face in everyday life. The study also provides insights into the current treatment of PD in Europe.

1.032 NON-MOTOR SYMPTOMS AND QUALITY OF LIFE IN PATIENTS WITH PARKINSON'S DISEASE

2012 ◽  
Vol 18 ◽  
pp. S18
Author(s):  
D. Joshi ◽  
P. Chatterjee ◽  
B. Kumar ◽  
A.Z. Ansari ◽  
V.N. Mishra ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Non Motor Symptoms
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