scholarly journals Cardiac masses due to tumors (diagnosis, clinical manifestations and surgical treatment)

2014 ◽  
Vol 95 (6) ◽  
pp. 806-810 ◽  
Author(s):  
D L Kranin
Keyword(s):  
Surgical Treatment ◽  
Malignant Tumors ◽  
Clinical Manifestations ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Low Grade ◽  
Imaging Results ◽  
Valvular Heart Diseases ◽  
Cardiac Myxomas

Aim. To summarize the experience on the diagnosis and surgical treatment of primary benign and malignant cardiac tumors. Methods. The paper describes 37 clinical observations of endocavitary primary benign and malignant cardiac tumors: 26 (70.3%) cases of cardiac myxoma, 5 (13.5%) - rhabdomyosarcoma, 2 (5.4%) - angiosarcoma, 1 (2.7% ) - leiomyosarcoma, 1 (2.7%) - fibrosarcoma, 1 (2.7%) - liposarcoma. Patients were 15 (40.5%) males and 22 (59.5%) females aged 18 to 65 years. Endocavitary cardiac tumors were diagnosed by noninvasive tests: echocardiography, computed tomography, magnetic resonance imaging. Results. Patients with primary benign and malignant cardiac tumors had variable clinical manifestations. Symptoms of astenoneurotic syndrome, auscultatory and cardiophonographic signs simulating acquired or congenital valvular heart diseases, which often have a positional relationship; low-grade fever of unknown origin, weight loss were registered. Paraneoplastic syndrome was characterized by an increase in erythrocyte sedimentation rate, leukocytosis, monocytosis, dysproteinemia, polycythemia, hypochromic anemia, increased levels of C-reactive protein. Surgical excision of 25 cardiac myxomas and 8 malignant tumors of the heart was performed with cardiopulmonary bypass, pharmacological cardioplegia and general hypothermia. In 1 case the tumor resection was combined with coronary artery bypass grafting. In 3 patients suffering from malignant tumors, explorative thoracotomy was performed. Surgical revision, emergency and planned microscopic studies of removed cardiac tumors allowed to establish the final clinical diagnosis. Hospital mortality among patients operated for cardiac myxomas was 4.0%, for cardiac malignant tumors - 27.3%. Conclusion. Timely surgical treatment of patients with primary cardiac benign tumors (myxomas) leads to recovery and is accompanied by a relatively low mortality; better results of patients with cardiac endocavitary tumors treatment depend on the early detection and timely radical surgical excision.

Surgical Treatment of Primary Cardiac Tumors—Experience with 45 Patients

1995 ◽  
Vol 3 (2) ◽  
pp. 49-52
Author(s):  
Lin Jue Yi ◽  
Chu Shu Hsun ◽  
Lee Yuan Teh ◽  
Wang Shoei Shen ◽  
Lin Fang Yue ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Left Atrium ◽  
Malignant Tumors ◽  
Thyroid Tissue ◽  
University Hospital ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Incomplete Resection ◽  
Long Term Result ◽  
Primary Cardiac Tumors

Primary cardiac tumors are very rare and the majority of them are histologically benign and surgically curable. During a 30-year period from 1963 to January 1993, 45 cases of primary cardiac tumors were surgically excised at the National Taiwan University Hospital, representing 0.52% of 8,695 open heart surgical cases during the same period. In this series, 42 cases (94%) were benign tumors; 39 (88%) were myxoma (30 female, 9 male), and 32 (82%) originated in the left atrium. None were discovered in the left ventricle. In all but the first 6 cases, tumors in patients with myxoma in the left atrium were successfully excised by the transseptal approach. There were 3 patients with rare benign tumors: intracardiac goiter, rhabdomyoma, and hemangioma respectively. The intracardiac goiter was completely excised with no ectopic thyroid tissue after operation and the other 2 received palliative resection. The latter 2 patients suffered no recurrence. Rhabdomyosarcoma, leiomyosarcoma and malignant lymphoma were noted in one patient each, all of whom died of low cardiac output in the early postoperative course. In our experience, the majority of primary cardiac tumors were benign and located in the left atrium. The long-term result of surgical treatment of benign cardiac tumors is excellent, even incases of incomplete resection, while the results from surgical treatment of malignant tumors is poor.

Surgical Treatment of Primary Cardiac Tumors

1997 ◽  
Vol 5 (2) ◽  
pp. 101-103 ◽  
Author(s):  
Gu Chun Jiu ◽  
Bao Wei Ke ◽  
Guo Bin Xun ◽  
Yuan Hong ◽  
Xiu Zhong Yi
Keyword(s):  
Surgical Treatment ◽  
Malignant Tumors ◽  
Right Atrial ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Long Term Result ◽  
The Right ◽  
Medical University ◽  
Primary Cardiac Tumors

During a 16-year period from 1980 to 1996, 101 patients with primary cardiac tumors underwent surgery at the 1st Affiliated Hospital of China Medical University, which represented 2.44% of 4142 open-heart surgical cases during this period. Most tumors were benign; 94 were myxomas, 2 were fibromas, and 1 was a hemangioma. Three myxomas were in the right atrium and 91 were in the left atrium. The 4 malignant tumors comprised 2 mesothelioma, 1 histiocytoma, and 1 right atrial malignant myxoma. All benign tumors were completely excised with 4.95% mortality. Only 1 malignant tumor was completely excised. In our experience, the long-term result of surgical treatment of benign cardiac tumors is excellent, whereas the prognosis for patients with malignant cardiac tumors is very poor. The incidence of malignant tumors was lower than in other studies.

scholarly journals Surgical Treatment Outcome of Salivary Gland Tumors

2019 ◽  
Vol 31 (3) ◽  
pp. 34-38
Author(s):  
Nibrass J. Kadhim ◽  
Salwan Y. Bede
Keyword(s):  
Salivary Gland ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Common Complication

Background: Salivary gland neoplasms constitute a group of heterogeneous lesions with complex clinicopathologic characteristics and distinct biological behavior. Numerous studies have suggested geographical variation, therefore the aims of this study were to analyze the characteristics of salivary gland neoplasms in two Iraqi centers and to analyze the postoperative complications that are encountered after surgical treatment of these tumors. Materials and Methods: A retrospective study of the patients who were treated for major and minor epithelial salivary gland tumors was conducted. The analyzed data included; demographic information (age and gender), the site of the tumor, the clinical manifestations, the histological type of the tumor, the type of the treatment and the postoperative complications. Results: Fifty seven patients were included in this study. The parotid gland was involved in most patients (n=37, 64.9%). Thirty five patients (61.4%) had benign tumors while 22 patients (38.6%) had malignant tumors. The mean age of patients with malignant tumors was 52.05 (±17.3) while of patients diagnosed with benign tumors was 41.6 (±11.4) years, the difference was statistically significant (p= 0.008). Surgical treatment consisted of superficial parotidectomy, total parotidectomy, surgical excision of the submandibular gland, surgical excision of minor salivary glands and maxillectomy. The most common complication was weakness of one or multiple branches of the facial nerve, complications were significantly associated with patients’ age, whereas gender and type of tumor whether benign or malignant did not affect the complication rate Conclusions: benign salivary gland tumors are more common than malignant tumors with no gender predilection and that patients who are diagnosed with malignant tumors are significantly older that patients with benign tumors, parotid gland is the most commonly affected gland with pleomorphic adenoma as the most frequent diagnosis. Facial nerve dysfunction was the most common complication and the complication rate was significantly associated with the age of patients.

Atypical Left Ventricular Myxoma: Unusual Echocardiographic and Histopathological Features

2018 ◽  
Vol 11 (4) ◽  
pp. NP129-NP131
Author(s):  
Sushil Azad ◽  
Nilanjan Dutta ◽  
Kuntal Roy Chowdhuri ◽  
Tarun Raina Ramman ◽  
Nishit Chandra ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Histopathological Examination ◽  
Cardiac Myxoma ◽  
Surgical Excision ◽  
Interatrial Septum ◽  
Left Ventricular ◽  
Cardiac Tumors ◽  
Complete Surgical Excision ◽  
Vascular Proliferation ◽  
Cardiac Myxomas

Cardiac myxomas are the most common primary cardiac tumors and are typically attached to the interatrial septum. Left ventricular myxomas are exceedingly rare and presentation in children is all the more uncommon. We report a case of left ventricular myxoma with very atypical cystic appearance raising an initial suspicion of a hydatid cyst. Subsequently, cardiac magnetic resonance imaging was done, which ruled out the diagnosis of hydatid cyst. Complete surgical excision was done through transaortic and transmitral route. Histopathological examination revealed it to be a cardiac myxoma with vascular proliferation, which on echocardiography had appeared as a polycystic lesion. This is a very unusual histopathological presentation of cardiac myxoma.

Twory w sercu – struktury anatomiczne i struktury patologiczne

2018 ◽  
Vol 22 (4) ◽  
Author(s):  
Beata Kucińska ◽  
Bożena Werner
Keyword(s):  
Transthoracic Echocardiography ◽  
Heart Defects ◽  
Congenital Defects ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Primary Tumors ◽  
Anatomical Structures ◽  
Imaging Results ◽  
Heart Tumors ◽  
Cardiac Masses

The increase in the availability of transthoracic echocardiography allows the diagnosis of not only congenital heart defects, which are the most common congenital defects in children, but also detection of cardiac masses such as thrombi, vegetations or heart tumors. Performing transthoracic echocardiography one should remember about normal anatomical structures in the atria and ventricles. The presence of central catheters and intracardiac leads favors the formation of thrombi in the heart. The vegetations which are characteristic for infective endocarditis mostly occur on the aortic and/or mitral valve. Primary cardiac tumors in children are very rare (approximately 0.2% of the population) and are usually oligosymptomatic. About 90% of them are benign tumors. The most common is the rhabdomyoma, which often coexists with tuberous sclerosis. The second most frequent tumor in children is a fibroma. Less common primary tumors in children are: teratomas, hemangiomas, lipomas, papillary fibroelastomas. In the differential diagnosis of cardiac masses comprehensive assessment and analysis of both imaging results, as well as medical history, physical examination, laboratory tests and other additional tests are extremely important.

Dendritic Interstitial and Myofibroblastic Cells at the Border of Salivary Gland Tumors

2001 ◽  
Vol 125 (2) ◽  
pp. 232-236
Author(s):  
Lori Soma ◽  
Virginia A. LiVolsi ◽  
Zubair W. Baloch
Keyword(s):  
Smooth Muscle ◽  
Salivary Gland ◽  
Malignant Tumors ◽  
Smooth Muscle Actin ◽  
Staining Intensity ◽  
Interstitial Cells ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Low Grade ◽  
Muscle Actin

Abstract Objective.—CD34-positive dendritic interstitial cells may be associated with the regulation of tumor growth. This association has been studied in various human neoplasms, especially skin tumors. In this study, we evaluated the distribution of dendritic interstitial cells and myofibroblastic cells at the tumor periphery of various benign and malignant salivary gland neoplasms. Methods.—Forty-nine cases of salivary gland tumors were selected: 16 pleomorphic adenomas, 12 Warthin tumors, 8 polymorphous low-grade tumors, 5 adenoid cystic carcinomas, 6 acinic cell carcinomas, and 2 mucoepidermoid carcinomas. Immunohistochemical analysis was performed by using antibodies for CD34 (dendritic cells) and α-smooth muscle actin (myofibroblast) on formalin-fixed, paraffin-embedded archival tissue. Staining intensity was graded as marked (3+), moderate (2+), weak (1+), and absent (0). Results.—Staining intensity for CD34 was 3+ in 24 (86%) of 28 benign tumors (pleomorphic adenomas and Warthin tumors) and 6 (29%) of 21 malignant tumors (polymorphous low-grade tumors, acinic cell carcinomas, adenoid cystic carcinomas, and mucoepidermoid carcinomas) and 2+ in 4 (19%) of 21 malignant tumors. None of the benign tumors displayed 2+ staining with CD34. Three (11%) of 28 benign and 11 (52%) of 21 of malignant tumors failed to stain with CD34. α-Smooth muscle actin staining was 3+ in 10 (36%) of 28 benign tumors and 6 (29%) of 21 malignant tumors, and 2+ in 11 (39%) of 28 benign and 2 (9%) of 21 malignant tumors. Five (18%) of 28 benign and 11 (52%) of 21 malignant tumors failed to stain with α-smooth muscle actin. Conclusion.—We conclude that the dendritic interstitial cells and myofibroblastic cells may be associated with the regulation of tumor growth in salivary gland tumors.

scholarly journals Ventricular Tachycardia Associated with Radiation-Induced Cardiac Sarcoma

2014 ◽  
Vol 41 (6) ◽  
pp. 620-625 ◽  
Author(s):  
Elijah H. Beaty ◽  
Wassim Ballany ◽  
Richard G. Trohman ◽  
Christopher Madias
Keyword(s):  
Ventricular Tachycardia ◽  
Right Ventricular ◽  
Ventricular Arrhythmias ◽  
Malignant Tumors ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Right Ventricular Free Wall ◽  
Undifferentiated Sarcoma ◽  
Electrocardiographic Changes ◽  
Radiation Induced

Cardiac tumors can lead to distinct electrocardiographic changes and ventricular arrhythmias. Benign and malignant cardiac tumors have been associated with ventricular tachycardia. When possible, benign tumors should be resected when ventricular arrhythmias are intractable. Chemotherapy can shrink malignant tumors and eliminate arrhythmias. We report the case of a 52-year-old woman with breast sarcoma whom we diagnosed with myocardial metastasis after she presented with palpitations. The initial electrocardiogram revealed sinus rhythm with new right bundle branch block and ST-segment elevation in the anterior precordial leads. During telemetry, hemodynamically stable, sustained ventricular tachycardia with right ventricular localization was detected. Images showed a myocardial mass in the right ventricular free wall. Amiodarone suppressed the arrhythmia. To our knowledge, this is the first report of ventricular tachycardia associated with radiation-induced undifferentiated sarcoma. We discuss the distinct electrocardiographic changes and ventricular arrhythmias that can be associated with cardiac tumors, and we review the relevant medical literature.

scholarly journals Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences

2013 ◽  
Vol 61 (8) ◽  
pp. 435-447 ◽  
Author(s):  
Jun Amano ◽  
Jun Nakayama ◽  
Yasuo Yoshimura ◽  
Uichi Ikeda
Keyword(s):  
Malignant Tumors ◽  
Cardiac Myxoma ◽  
World Health ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
New Classification ◽  
Metastatic Tumors ◽  
Great Vessels ◽  
Tumor Like Lesions

Abstract Tumors of the heart and the great vessels are very rare disease, and there are many disorders such as tumors originated from the heart and great vessels, metastatic tumors, and tumor-like lesions which do not fit into the usual concept of tumor or neoplasm; thus, it is very difficult to classify these tumors. We proposed a new classification of cardiovascular tumors for clinical use based on the accumulated biological analyses and clinical data of the reported literatures and our own study as benign tumors, malignant tumors, ectopic hyperplasia/ectopic tumors/others, and tumors of great vessels, with reference to the series of Atlas of tumor pathology of the Armed Forces Institute of Pathology and the recent World Health Organization classification of cardiac tumors issued in 2004. More than 50 disorders have been reported as tumors originated from the cardiovascular system, and various metastatic tumors from nearby organs, distant lesions, and intravascular extension tumors to the heart were reported. Based on the new classification, we reviewed epidemiology and incidence of cardiovascular tumors. Metastatic tumors are more frequent than tumors originated from the heart and great vessels, and cardiac myxoma is the most frequent tumors in all cardiac tumors.

scholarly journals Left Atrial Myxoma with Tricuspid Regurgitation: Pathophysiology, Diagnostic Approach, and Management

2015 ◽  
pp. 28-3
Author(s):  
Prima Almazini ◽  
Bambang Budi Siswanto ◽  
Nani Hersunarti ◽  
Rarsari Soerarso ◽  
Amiliana M Soesanto
Keyword(s):  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Definitive Treatment ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Gold Standard Method ◽  
Left Atrial Myxoma ◽  
Associated Conditions ◽  
Cardiac Myxomas ◽  
Primary Cardiac Tumors

Cardiac myxomas are the most common primary cardiac tumors. Myxoma are more common in women. Clinical manifestations can mimic many cardiac and noncardiac conditions. Transthoracic echocardiography (TTE) is the gold standard method in the diagnosis of cardiac myxoma. The management of cardiac myxoma are medical therapy for the treatment of associated conditions and surgical removal as the definitive treatment.

scholarly journals Primary Cardiac Rhabdomyosarcoma in a child -- A case report

2020 ◽  
Author(s):  
KRISHNA PRASAD MARAM ◽  
Vikram Kudumula ◽  
Dilip Ratti
Keyword(s):  
Case Report ◽  
Left Ventricle ◽  
Right Ventricle ◽  
Malignant Tumor ◽  
Right Atrium ◽  
Malignant Tumors ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Cardiac Rhabdomyosarcoma ◽  
Primary Cardiac Tumors

Primary cardiac tumors are rare in children, usually consist of benign tumors like rhabdomyomas and fibromas that may spontaneously regress. Primary malignant tumors are extremely rare even in adults and very few paediatric cases were reported in literature. Rhabdomyosarcoma is a rare primary malignant tumor in children and most of the reported cases occur in right ventricle, left atrium and right atrium. We report a 15 month old child with primary rhabdomyosarcoma of left ventricle presenting in cardiac tamponade and circulatory failure.

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