scholarly journals Features of etiopathogenesis of psychosomatic and somatoform disorders

2012 ◽  
Vol 93 (3) ◽  
pp. 465-468
Author(s):  
L P Marincheva ◽  
M V Zlokazova ◽  
A G Solov’ev
Keyword(s):  
Autonomic Dysfunction ◽  
Somatoform Disorders ◽  
Control Group ◽  
Psychosomatic Disorders ◽  
Adaptive Responses ◽  
Coping With Stress ◽  
Study Results ◽  
The Mean ◽  
Questionnaire Surveys ◽  
The Individual

Aim. To identify the features of etiopathogenesis of somatoform and psychosomatic disorders in adolescents. Methods. Examined were 426 adolescents and their families. The main group - 321 patients of the Kirov City Children’s Clinical Hospital, which included two subgroups: 117 adolescents with somatoform autonomic dysfunction, and 204 - with psychosomatic disorders; the mean age was 15.1±1 years. The control group consisted of 105 adolescents who were students of secondary schools in the city of Kirov with the first group of health; the mean age was 15.1±1 years. The clinical-psychopathological method of investigation, questionnaire surveys, and experimental psychological tests were used in order to perform the study. Results. The conducted study confirms the multifactor nature of the pathogenesis of psychosomatic disorders (identified was the importance of biological, psychological and social factors) and makes it possible to suggest that the onset of symptoms of psychosomatic disorders is formed according to the main stages of the nonspecific response to stress, from the autonomic neurotic reactions during somatoform autonomic dysfunction (at the stage of resistance) to the development of the psychosomatosis picture - during the development of psychosomatic disorders (at the exhaustion stage). The level of disease development is determined by both the individual predisposition and the spectrum of adaptive responses to stress. All this confirms the need for earliest detection of somatoform autonomic dysfunction in order to prevent the development into a chronic process and its progression. Conclusion. Complex treatment is of great importance, including the personal-oriented psychotherapy aimed at the development of adaptive mechanisms for coping with stress.

scholarly journals The individual empowerment program improves glycemic and lipid controls in admitted type 2 DM patients

2018 ◽  
Vol 21 (2) ◽  
pp. 113-117
Author(s):  
Ampornpan Theeranut ◽  
Nonglak Methakanjanasak ◽  
Pattama Surit ◽  
Wasana Ruaisungnoen ◽  
Kittisak Sawanyawisuth ◽  
...  
Keyword(s):  
Intervention Group ◽  
Control Group ◽  
P Value ◽  
Inpatient Setting ◽  
Short Term ◽  
The Mean ◽  
The Individual ◽  
Diabetes Patients ◽  
Empowerment Program

Aim. To evaluate the short-term effects of the empowerment program on glycemic and lipid profiles in an inpatient setting for DM type 2 patients. Materials and methods. This was a quasi-experimental study conducted between October 2013 and June 2015. We enrolled diabetes patients admitted to the hospital, age over 35 years, and HbA1c 7%. During the admission, the intervention group received the empowerment course three times prior to discharge, the control group received standard diabetes and nursing care. All patients body weight, HbA1c, HDL-c, and LDL levels were evaluated at three and six months after discharge. All outcomes were compared between the control and intervention group. Results. A total of 57 diabetes patients participated in the study, with 27 in the intervention group and 30 in the control group. The intervention group had significantly higher HbA1c levels than the control group (10.3% vs 8.0%; p value 0.001). After discharge, the mean HbA1c and LDL-c levels of the intervention group were significantly lower than those of the control group at three and six months, while the mean HDL-c level of the intervention group was significantly higher than that of the control group at six months (1.54 vs 1.29 mmol/L; p value 0.001). The average body mass index of the intervention group was also significantly lower than that of the control group at six months (22.74 vs 25.54 kg/m2; p value = 0.016). Conclusion. The individual empowerment program improved short-term glycemic and lipid outcomes in admitted diabetes mellitus patients.

scholarly journals Cardiovascular and hematologic effects produced by chronic treatment with etoricoxib in normotensive rats

2009 ◽  
Vol 24 (3) ◽  
pp. 206-210 ◽  
Author(s):  
Nilo César do Vale Baracho ◽  
Guilherme Pedrosa Guizelli ◽  
Beatriz Leone Carmello ◽  
Danielle de Souza Sanches ◽  
Felipe Moraes Costa Silva ◽  
...  
Keyword(s):  
Blood Cells ◽  
Chronic Treatment ◽  
Experimental Period ◽  
Control Group ◽  
Histopathological Changes ◽  
Study Results ◽  
Significant Difference ◽  
Hematological Effects ◽  
The Mean ◽  
Hematological Changes

PURPOSE: Evaluate the cardiovascular and hematological effects produced by chronic treatment with two dosis of etoricoxib in Wistar normotensive rats. METHODS: Thirty rats have been used and divided into one control group and two etoricoxib (10mg/kg and 30mg/kg) treatments groups for 60 days. The mean arterial pressure (MAP) was taken during the whole experimental period and at the end of this period, under anesthesia blood samples were taken, and further the withdrawn of the aorta, heart, brain, liver, and kidneys for the anatomopathologic study. RESULTS: The treatment with etoricoxib (30mg/Kg) produced a significant increase of the MAP from the 28th day of the experiment and from the platelets when compared to the control group and to the group treated with 10mg/Kg, besides producing a highly significant difference in hematocrit and in the red blood cells in relation to the control group. On the other hand the treatment with etoricoxib has not caused histopathological changes when compared to the control. CONCLUSION: These data show that the chronic treatment with etoricoxib leads to increase of the MAP, and to important hematological changes which seem to be associated to the hemoconcentration although not producing anatomopathological significant changes.

Lipid-based Nose Ointment for Allergic Rhinitis

2005 ◽  
Vol 133 (5) ◽  
pp. 754-761 ◽  
Author(s):  
Urban Wilhelm Geisthoff ◽  
Andreas Blum ◽  
Marianne Rupp-Classen ◽  
Peter-Karl Plinkert
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Congestion ◽  
Tertiary Care ◽  
Control Group ◽  
Significant Drop ◽  
Intention To Treat ◽  
Study Results ◽  
Tertiary Care Centers ◽  
The Individual ◽  
Individual Scores

OBJECTIVE: To assess the efficacy of a lipid-based nose ointment in treating allergic rhinitis. STUDY DESIGN AND SETTING: Prospective, open, randomized, controlled clinical study in the outpatient departments of 2 tertiary care centers. RESULTS: No specific adverse effects were observed. The nose ointment under investigation led to a significant improvement in sneezing and nasal itching (17 patients). There was no significant change for nasal congestion and rhinorrhea in the intention-to-treat sets. However, there was still a significant drop of the mean relative total symptom score derived from the individual scores. All scores remained unchanged in the untreated control group (16 patients). CONCLUSION: Topical application of the nose ointment as a supportive treatment leads to a significant improvement of symptoms in allergic rhinitis. SIGNIFICANCE: The prevalence of allergic rhinitis is about 10% to 20% in the population. Our study results are encouraging and should be assessed in further research because changes in the therapeutic guidelines may be suggested.

scholarly journals The efficacy of miswak (Kayu sugi) containing toothpaste on dental plaque accumulation

2018 ◽  
Vol 30 (1) ◽  
pp. 24
Author(s):  
Nunung Rusminah ◽  
Indra Mustika Setia Pribadi ◽  
Komala Thillainathan
Keyword(s):  
Dental Plaque ◽  
Enzyme Inhibitors ◽  
Plaque Index ◽  
Control Group ◽  
Salvadora Persica ◽  
Index Reduction ◽  
Study Results ◽  
Detergent Enzyme ◽  
The Mean ◽  
Institute Of Technology

Introduction: Salvadora persica, also known as miswak (Kayu sugi), has been used as natural toothbrushing compound for centuries. Many research suggested that it contains medically beneficial properties such as abrasives, antiseptics, astringent, detergent, enzyme inhibitors, and fluoride. The objective of this study was to assess the efficacy of miswak containing toothpaste on dental plaque accumulation. Methods: The total of 30 subjects consisted of male students of Bandung Institute of Technology, aged between 18 – 26 years old. The plaque value was measured using the Turesky Gilmore & Glickman Index Modification of Quigley & Hein at baseline (day 0), day 1, day 3, and day 7. Commercial toothpaste (Pepsodent®) was used as the control group in this pre and post-test designed, single-blind study. Results: After analysed using the paired t-test, the data showed that the mean plaque index of respondents using miswak and non-miswak containing toothpaste from baseline until day 7, were 1.70/1.19 and 1.61/1.44 respectively (p < 0.05). The mean plaque index reduction of respondents using miswak and non-miswak containing toothpaste from baseline until day 7, were 0.39 and 0.25 respectively (p = 0.00). Conclusion: Both kinds of toothpaste were able to reduce plaque, but miswak containing toothpaste was found to be more effective in reducing dental plaque accumulation.

scholarly journals Effect of Foetal Movement Counting on Prenatal Attachment and Maternal Worries among Primigravidas- A Longitudinal Study

2021 ◽  
Author(s):  
Jignya Vinodbhai Asari ◽  
Anjali Pushkar Tiwari
Keyword(s):  
Longitudinal Study ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Prenatal Attachment ◽  
Study Results ◽  
Significant Difference ◽  
The Mean ◽  
Foetal Movement ◽  
And Control

Introduction: Pregnant woman experience various physical, emotional, and hormonal changes that may cause anxiety. The anxiety and worries can be decreased by sharing information about the developing child, like foetal body movement. Aim: To assess effect of Foetal Movement Counting (FMC) on prenatal attachment and maternal worries among primigravida mothers. Materials and Methods: A longitudinal study was carried out among primigravida mothers of selected Hospitals of Central Gujarat using proforma of Cranley’s maternal foetal attachment scale and Cambridge worry scale. The study was conducted from March 2019 to July 2020. Eighty participants were recruited by convenient sampling 40 in each study group and control group. The study group were provided with foetal movement chart and the participants were asked to record foetal movements for seven consecutive days, twice a day for 20 minutes. Post assessment of prenatal attachment and maternal worries was done using tools of data collection for both study and control group. Chi- square test was used to test the significance (p-value <0.05). Results: The study results revealed that in study group mean score for prenatal attachment was 79.43 at the start and improved to 101.25 (p-value <0.001) after seven days of FMC. In control group, the mean score for prenatal attachment did not show significant difference pre-test and post-test (74.20 vs 74.85, p-value=0.077). In study group, the mean Cambridge worry scale score was 36.55 which came down to 20.28 (p-value <0.001) after seven days, while in control group it was 41.38 at the beginning and 41.30 after seven days (p-value=0.998). Conclusion: Foetal Movement Counting was found to improve maternal foetal attachment and reduce maternal worries. FMC can be routinely and effectively promoted among the pregnant population to help them achieve a positive pregnancy experience and outcome.

scholarly journals Influence of classic massage on cardiac autonomic modulation

2016 ◽  
Vol 29 (3) ◽  
pp. 487-496 ◽  
Author(s):  
Mário Augusto Paschoal
Keyword(s):  
Test Group ◽  
Well Being ◽  
Control Group ◽  
Autonomic Modulation ◽  
Cross Sectional ◽  
Mean Values ◽  
Cardiac Autonomic Modulation ◽  
Body Tissues ◽  
Study Results ◽  
The Mean

Abstract Introduction: Massage can be defined as the rhythmic and smooth manipulation of body tissues, with the aim to promote health and well-being. Objective: To assess the influence of classic massage on cardiac autonomic modulation. Methods: Cross-sectional study that evaluated healthy participants, with mean age between 18 and 25 years, divided into two groups: test group (TG, n=11) and control group (CG, n=10). The TG had their heartbeat recorded for 5min before receiving a classic massage for 40min and during three periods after this procedure: 0-5min, 5-10min and 10-15min. The CG had their heartbeats recorded at the same time; without receive massage. Cardiac autonomic modulation was investigated by heart rate variability (HRV). Results: The mean values of HRV rates were: pNN50, respectively, for the TG: before massage (10.5 ± 9.5%), and after massage: 0-5min (11.6 ± 7.2%), 5-10min (12.1 ± 8.0%) and 10-15min (11.1 ± 7.9%), with no significant statistical difference. The same result was found for the mean values of rMSSD index of the TG; before massage: 52.1 ± 46.2 ms, and after massage: 0-5min (50.0 ± 21.6ms), 5-10min (52.0 ± 27.4 ms) and 10-15min (48.2 ± 21.1 ms). Also, the values of LFnuand HFnu indexes did not change significantly before and after massage, and they were not statistically different from the values presented by the control group. Conclusion: The study results suggest that one session of classic massage does not modify cardiac autonomic modulation in healthy young adults.

The pattern of growth in the early lifecycle of individual Sepia pharaonis

2004 ◽  
Vol 55 (4) ◽  
pp. 415 ◽  
Author(s):  
Jonathan W. Minton
Keyword(s):  
Growth Rate ◽  
Growth Phase ◽  
Growth Curves ◽  
Maximum Size ◽  
Control Group ◽  
Sepia Pharaonis ◽  
Second Growth ◽  
The Mean ◽  
R Value ◽  
The Individual

The pattern of growth in the early lifecycle of the pharaoh cuttlefish, Sepia pharaonis, was investigated by rearing hatchlings at 26°C in two separate trials. In each trial, the mean weight and mantle length (ML) was recorded in 5-day intervals. In addition, in each trial the growth of 20 group-reared cuttlefish was measured as a control to compare against the individual data. After 60 days of growth, the mean size for individuals in trial 1 was 2.75 g (maximum size 3.32 g) and in trial 2 was 12.76 g (maximum size 14.99 g) at 90 days. Each individual went through distinct growth phases during the first 90 days after hatching. The first growth phase matched exponential curves with an R-value of 0.98 or better, and the second growth phase corresponded with linear and power growth curves at an R-value of 0.98 or better. In trial 1, the mean growth rate for individuals during the first phase was 5.91% BW day–1 and the control group growth rate was 6.36% BW day–1. In trial 2, the mean growth rate for individuals during the first phase was 6.06% BW day–1 and the control group growth rate was 6.70% BW day–1.

scholarly journals The Effect of Breastfeeding on Photorefractive Keratectomy Outcomes: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Siamak Zarei-Ghanavati ◽  
Amir Reza Daneshmand Eslami ◽  
Alireza Eslampoor ◽  
Saeed Shokouhi Rad ◽  
Saeed Akhlagi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort ◽  
Photorefractive Keratectomy ◽  
Control Group ◽  
P Value ◽  
Study Results ◽  
Standard Deviation Range ◽  
The Mean ◽  
Duration Of Breastfeeding ◽  
Group Post

Abstract Purpose To assess the refractive results, visual function, and safety of photorefractive keratectomy (PRK) in myopic breastfeeding women and compare them to healthy matched female controls. Methods Twelve mothers (23 eyes) who underwent PRK while they were still breastfeeding (B group) and continued it for at least three months participated in this retrospective matched cohort study. Twelve women (23 eyes) who were matched for age, refractive error, and operation data (NB group) were selected as the control group. Post-PRK results and complications were compared between the two groups. Results Twenty four breastfeeding mothers with a mean age of 29.70±1.8 (Standard Deviation) (range from 27 to 33years) were included. The average age in the study and the control group were 29.83 ± 1.80 and, 29.58 ± 1.98, prospectively, (P-value=0.749, T-test, poverty 0.1). The mean duration of breastfeeding was 47 weeks before surgery and 35 weeks after surgery. Conclusion Our study results did not indicate the adverse effects of breastfeeding on the results of PRK surgery. It seems that performing PRK is safe in the breastfeeding period.

scholarly journals The Effect of Breastfeeding on Photorefractive Keratectomy Outcomes: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Siamak Zarei-Ghanavati ◽  
Amir Reza Daneshmand Eslami ◽  
Alireza Eslampoor ◽  
Saeed Shokouhi Rad ◽  
Saeed Akhlagi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort ◽  
Photorefractive Keratectomy ◽  
Control Group ◽  
P Value ◽  
Study Results ◽  
Standard Deviation Range ◽  
The Mean ◽  
Duration Of Breastfeeding ◽  
Group Post

Abstract Purpose To assess the refractive results, visual function, and safety of photorefractive keratectomy (PRK) in myopic breastfeeding women and compare them to healthy matched female controls. Methods Twelve mothers (23 eyes) who underwent PRK while they were still breastfeeding (B group) and continued it for at least three months participated in this retrospective matched cohort study. Twelve women (23 eyes) who were matched for age, refractive error, and operation data (NB group) were selected as the control group. Post-PRK results and complications were compared between the two groups. Results Twenty four breastfeeding mothers with a mean age of 29.70±1.8 (Standard Deviation) (range from 27 to 33years) were included. The average age in the study and the control group were 29.83 ± 1.80 and, 29.58 ± 1.98, prospectively, (P-value=0.749, T-test, poverty 0.1). The mean duration of breastfeeding was 47 weeks before surgery and 35 weeks after surgery. Conclusion Our study results did not indicate the adverse effects of breastfeeding on the results of PRK surgery. It seems that performing PRK is safe in the breastfeeding period.

scholarly journals Neurohistological changes in the cerebellar cortex of adult Wistar rats following lead acetate induced cortical damage

2021 ◽  
Vol 15 (3) ◽  
pp. 182-188
Author(s):  
Ajibade AJ ◽  
Ogundero SA
Keyword(s):  
Cerebellar Cortex ◽  
Lead Acetate ◽  
Wistar Rats ◽  
Histological Study ◽  
Control Group ◽  
Hair Dye ◽  
Study Results ◽  
Group A ◽  
The Mean ◽  
The Brain

This study investigated the neurohistological effect of lead acetate on cerebellar cortex of adult wistar rats. Lead is a common industrial poisonous substance that its prevalence in the environment exhibits toxic effect which makes different organs & tissues especially the central nervous system vulnerable to lead exposure. Lead is however, found useful applications in diverse items of daily needs like paints, water pipes, car batteries, leaded gasoline, ammunition, cosmetics, hair dye, airplanes, shielding for x-ray machines. Thirty-six (36) adult wistar rats of both sexes weighing between 120-250 grams were randomly grouped into four groups. Group A, B, C and D each group containing seven (9) rats. Group A rats served as the control, and was maintained on standard feed and water for 28 days, group B, C and D rats were treated orally once daily with 0.09g/kg, 0.18g/kg and 0.2g/kg of lead acetate respectively for 28 days. The weights of the wistar rats were recorded on weekly basis during the treatment. All the wistar rats in group A, B, C and D were sacrificed by cervical dislocation on the 29th day of the treatment. The brain was removed and weighed with a sensitive balance and the cerebellum of each rats was then fixed in 10% formol saline, the tissue was processed and stained with Hematoxylin and Eosin for histological study. Results showed that the mean body weights of the wistar rats significantly decreased in the treated groups when compared with the control group. The mean brain weights of the lead treated groups showed a significant decrease when compared to the control group. Histological study of the brain (cerebellar cortex) of the treated groups demonstrated degenerative changes revealed shrinkage, reduced sized and cellular loss of the Purkinje cells with vacuolations in the Purkinje cell layer compared with normal cerebellar histoarchitecture in the control. The study concluded that lead acetate has a neurotoxic effect on the cerebellar cortex of adult wistar rats which may ultimately impair some cerebellar functions.

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