scholarly journals Measurements of the optical density of the alveolar process bone tissue of the jaws during periodontal diseases with the use of three-dimensional computed tomography

2012 ◽  
Vol 93 (4) ◽  
pp. 660-662 ◽  
Author(s):  
N N Bondarenko ◽  
E V Balakhontseva
Keyword(s):  
Periodontal Disease ◽  
Bone Tissue ◽  
Optical Density ◽  
Periodontal Diseases ◽  
Three Dimensional ◽  
World Health ◽  
Alveolar Process ◽  
Treatment Needs ◽  
Moderate Severity ◽  
Periodontal Tissues

Aim. To determine the optical density of the alveolar process bone tissue in normal conditions and during various forms of periodontal pathology. Methods. With the use of clinical and radiographic methods examined were 120 patients (with a healthy periodontium, with chronic generalized catarrhal gingivitis of moderate severity, with chronic periodontitis of a mild, moderate and severe degree). On the three-dimensional computer tomograms in each group of patients determined was the optical density of the alveolar process bone tissue from the medial and distal sides of the root of the following teeth 1.6, 1.7, 2.7, 2.6, 3.6, 3.7, 4.7, 4.6, 1.1, 3.1 (the teeth numbers have been recommended by the World Health Organization in order to determine the index of treatment needs of the periodontal disease), and studied were its changes depending on the severity of periodontal disease. Statistical analysis was performed using computer programs «Microsoft Excel», «Biostatistica». Results. In periodontal disease noted was a reduction in the optical density of bone tissue of the alveolar processes of the jaws with a firm relashionship with the severity of disease. In chronic generalized catarrhal gingivitis of moderate severity the optical bone density ranged from 40.445±1.264 to 633.744±5.226 arbitrary units, in mild forms of chronic generalized periodontitis - from -119.664±1.511 to 344.972±4.019, in moderate forms of chronic generalized periodontitis - from -232.589±3.088 to 203.841±1.604, in severe chronic generalized periodontitis - from -464.080±2.398 to -53.991±1.435 arbitrary units. Conclusion. Changes in optical density of bone tissue of the alveolar process of the jaws is an objective criterion for evaluating the status of periodontal tissues, an important diagnostic feature, which also makes it possible to predict the course of the disease and monitor the effectiveness of treatment.

scholarly journals MODERN SCIENTIFIC VIEW ON THE OPTIMIZATION OF TREATMENT OF PERIODONTAL DISEASES

2021 ◽  
Vol 21 (1) ◽  
pp. 178-183
Author(s):  
V.O. Kateryniuk
Keyword(s):  
Periodontal Disease ◽  
Bone Tissue ◽  
Periodontal Diseases ◽  
The Body ◽  
Alveolar Process ◽  
Social Significance ◽  
Subsequent Formation ◽  
Periodontal Tissues ◽  
Microbial Invasion ◽  
Rehabilitation Measures

The article presents a retrospective review of professional domestic and foreign literature on modern aspects of treatment of inflammatory periodontal diseases, including vector therapy, plasmalifting, which can be used in various forms of this pathology. Periodontal diseases are one of the most pressing problems of dentistry, which has not only general but also great social significance, due to the high prevalence, intensity of the process, the subsequent formation of chronic odontogenic foci of infection, tooth loss at a young age and adverse effects on the body. Treatment of periodontal disease is a complex and lengthy process that includes general methods of influencing the pathophysiological processes occurring in the body, both local - therapeutic, orthopedic and surgical measures. Before planning treatment, the dentist should determine the patient's medical and dental history, conduct clinical and radiological examinations, determine the degree of loss of the alveolar ridge, functional disorders of the dental system and the possibility of their correction. Depending on this, determine the plan of treatment and rehabilitation measures, the sequence of medical interventions. The main task of periodontal treatment is to optimize the conditions for maintaining a healthy dentition and restoring its physiological functions. The difficulty of treating inflammatory periodontal diseases is that known and standard methods (antibacterial therapy and courses of local therapy) do not always give a positive result and a long period of remission. Therefore, to improve the quality of medical care for patients with periodontal pathology, it is necessary to introduce new innovative methods of treatment in dental practice. Given the patterns of pathophysiological processes occurring in periodontal tissues and bone tissue of the alveolar process, to date, several stages of treatment and rehabilitation measures have been proposed. The first stage is the elimination of the pathogenic action of microbial factors and inflammatory processes in periodontal tissues. Microbial invasion and the inflammatory reaction of periodontal tissues caused by it activate the processes of osteoclastical bone resorption. The task of the second stage of treatment and rehabilitation measures is to restore the physiological structure of gums and bone by normalizing metabolic processes in periodontal tissues, reducing the activity of resorption processes and stimulating reparative osteogenesis in the bone tissue of the alveolar process and the body in general, surgical treatment. At the third stage of treatment and rehabilitation measures, teeth with a significant degree of atrophy of the alveolar process are removed, which cannot be used for prosthetics. To restore the integrity of the dentition, even distribution of masticatory load, appropriate prosthetics are performed. The use of the latest methods contributes to the effective treatment of periodontal disease in the early stages, stabilization of the process at deeper stages, in some cases helps to avoid surgery.

scholarly journals The Assessment of Periodontal Status and Treatment Needs of the Adult Population Aged 34-44 Residing in Lublin Province and Visiting the Dentist Regularly

2014 ◽  
Vol 124 (2) ◽  
pp. 86-88
Author(s):  
Małgorzata Stodókiewicz ◽  
Joanna Krawczyk ◽  
Jacek Szkutnik ◽  
Marcin Berger
Keyword(s):  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Adult Population ◽  
World Health ◽  
Treatment Needs ◽  
Periodontal Status ◽  
Periodontal Tissues ◽  
Periodontal Index ◽  
Community Periodontal Index ◽  
Health Organization

Abstract Introduction. Periodontitis is a group of inflammatory disorders affecting periodontal tissues. This condition manifests by a progressive destruction of the alveolar bone, subsequently leading to tooth loss. World Health Organization introduced Community Periodontal Index of Treatment Needs in order to gain data regarding periodontal health and treatment needs of people with periodontitis Aim. To evaluate the periodontal status of citizens living in the city of Lublin and its surrounding, using Community Periodontal Index of Treatment Needs (CPITN). Material and methods. Community Periodontal Index of Treatment Needs was used to assess the periodontal status among 180 patients aged 35-44 residing in Lublin and the area around it. Results. Periodontal diseases have been observed in over 90% of the examined population. Treatment need index TN1 has referred to 26.11% of the patients, TN2 – 61.67% and TN3 – 2.22% respectively. Conclusions. Patients who visit the dentist regularly have a better periodontal status as compared to groups randomly selected.

Abstract TP85: Impact of Periodontal Disease and -Bacteria on Intracranial Aneurysms

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Shotaro Yoshioka
Keyword(s):  
Periodontal Disease ◽  
Intracranial Aneurysms ◽  
Inflammatory Responses ◽  
Periodontal Diseases ◽  
Gram Negative Bacteria ◽  
Periodontal Pathogens ◽  
Treatment Needs ◽  
Gram Negative ◽  
Periodontal Tissues ◽  
Periodontal Index

Introduction: Periodontal Gram-negative bacteria and their products can initiate inflammatory responses in periodontal tissues with systemic consequences. They are associated with the pathogenesis of atherosclerosis and ischemic stroke. Local inflammation and oxidative stress play a crucial role in the pathophysiology of intracranial aneurysms (IAs). Under the hypothesis that the severity of periodontal disease is associated with the formation and rupture of IAs we assessed which periodontal pathogens contribute to the pathogenesis of IAs. Methods: We enrolled patients with ruptured- (n=5, age 60±11.9) and unruptured IAs (n=13, age 67±6.1) and controls without IAs (n=7, age 58±8.5); their prior informed consent was obtained. The severity of periodontitis was recorded using the community periodontal index (CPI) of the Treatment Needs code. Subgingival plaques (n=23) were evaluated with the quantitative real-time PCR assay to check for the Gram-negative bacteria Aggregatibacter actinomycetemcomitans (Aa), Fusobacterium nucleatum, Treponema denticola, Prevotella intermedia (Pi), Tannerella forsythia, and Porphyromonas gingivalis (Pg). Plasma IgG titers of antibody against Pg, Pi, Aa, and Eikenella corrodens were evaluated by ELISA. Results: The CPI was significantly higher in patients with IAs than the controls (2.7 vs 1.9, p<0.05) and their DNA level of subgingival plaques and their plasma IgG titers of Pg were also higher. Periodontal disease was more severe and the plasma IgG titers of Pg were higher in patients with ruptured- than unruptured IAs, suggesting that Pg is associated not only with the formation but also the rupture of IAs. Conclusions: We present evidence that severe periodontal disease and Pg infection may be involved in the pathophysiology of IAs. The management of periodontal diseases may help to prevent the formation and rupture of IAs.

scholarly journals COMPARATIVE EXPERIMENTAL AND CLINICAL EVALUATION OF OSTEOGENIC PROPERTIES OF BONE MARROW AND FATTY AUTOLOGICAL STOMATIC CELLS

2018 ◽  
pp. 22-26
Author(s):  
V. F. Kutsevlyak ◽  
V. I. Kutsevlyak ◽  
I.V. Tsyganova
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Adipose Tissue ◽  
Bone Tissue ◽  
Periodontal Diseases ◽  
Complex Treatment ◽  
Alveolar Process ◽  
Surgical Methods ◽  
Regeneration Of Bone Tissue ◽  
Regeneration Of Bone

The success of restorative surgical treatment of periodontal inflammatory diseases is largely determined by the processes of reparative regeneration of bone tissue of the patient. Analysis of the causes of unsuccessful treatment of such patients suggests that the ways of overcoming them consist both in improving the technology of the surgical intervention itself and in creating optimal conditions for regeneration of bone tissue. One of the most promising directions for correcting the regeneration process is the transplantation of stem cells of various origin. Using the method of directed regeneration of bone tissue of the alveolar process with the addition of autologous stem cells in periodontal surgery in the treatment of generalized periodontitis II and III degree of severity will not only eliminate the inflammatory process, but also anatomically restore the structural components of the periodontal, in particular, the alveolar bone. The purpose of the study was to compare the osteogenic properties of bone marrow and adipose tissue cells. A complex of experimental and clinical research has been carried out. In experimental studies on the effects of rabbit's autologous cells derived from bone marrow and adipose tissue, rabbits-male Chinchilla breeds of 1 year old were used to heal the pustular defects of the alveolar process; the animals were divided into 8 ordinal groups. Under thiopental anesthesia a defect of bone tissue was created at a depth of the cortical plate in the size of 0.027 cm3, which was filled as follows: a defect under the cluster; Defect and Collapan L; defect, 100000 units bone marrow stem cells, Collapan L.; defect, 500000 units Stem cells of adipose tissue, Collapan L, defect, 1 million units. CCMC, Collapan L.; defect, 100000 units SCJT, Collapan L.; defect, 500000 units SCJT, Collapan L.; defect, 1 million units. SCJT, Collapan L., after which the wound was sutured. Animals were brought out from the experiment by air embolism for 42 or 90 days. In the initial survey, the average indexes of periodontal disease in patients of both groups were equal. Radiologically, in patients of the experimental group, an increase in the height of interalveolar septal walls was determined at 1-1.5 mm, in comparison with preoperative orthopantomograms. There was an increase in the density of the spongy bone of the interdental partitions, an increase in its X-ray contrast. The use of autologous stem cells at the surgical stage of complex treatment of periodontal diseases has evident advantages over the traditional surgical methods of treating these diseases, since restoration of the periodontal structure is restored, periodontal pockets are eliminated, long remission is established, which is confirmed by the improvement of the level of oral hygiene, the normalization of the index assessment of the periodontal condition, processes of bone tissue regeneration. Thus, we have proved that the use of autologous stem cells at the surgical stage of complex treatment of periodontal diseases has evident advantages over traditional surgical methods of treatment of these diseases, since restoration of periodontal structure is restored, periodontal pockets are eliminated, long-term remission is established. Аs a result of the evaluation of the dynamics regeneration of bone defects of the mandible in case of the introduction of stem cells with Collapan into the defect zone, we found that the course was most favorable for the administration of bone tissue stem cells comparing to the introduction of adipose tissue stem cells.

scholarly journals DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE OF MICROBIAL FLORA IMBALANCE IN GINGIVAL BIOFILM

2020 ◽  
Vol 5 (2) ◽  
pp. 76-82
Author(s):  
G. A. Loban ◽  
T. O. Petrushanko ◽  
V. V. Chereda ◽  
M. O. Faustova ◽  
M. M. Ananieva ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Prognostic Significance ◽  
Fluid Composition ◽  
Dental Tissues ◽  
Periodontal Tissues ◽  
Dmf Index ◽  
Increased Risk ◽  
Hard Dental Tissues

Background. Periodontal tissues inflammatory diseases are widespread among young people. Objective. This study was aimed at elaborating the method to assess risks of periodontal inflammatory diseases and determining its efficacy depending on the state of dental tissues, gum tissues and sex.          Methods. The study included 182 students (93 men, 89 women) aged 19-29: 22 individuals had no lesions of hard dental tissues and no signs of periodontal disease; 51 individuals were found to have DMF index <6; 52 individuals – DMF index ≥6; 57 individuals were diagnosed with chronic catarrhal gingivitis. Primary groups were formed in autumn; re-examination was carried in spring. The research participants were assessed for detection of risks of periodontal inflammatory disease by the method developes by the authors (Patent UA 54041). Results. The study revealed that the risk of development of preiodontitis increases in individuals with high caries and gingivitis intensity. In spring, more individuals suffer from microbial imbalance in in the composition of gingival sulcus fluid and decrease in the mean stability coefficient value that indicates an increased risk of inflammatory periodontal disease development. Women were less likely to experience seasonal dysbiotic changes in the gingival sulcus fluid composition compared with men. Conclusions. The method suggested for assessment of the risk of periodontal inflammatory diseases is of high informativeness. It allows clinicians detecting early pre-nosological signs of oral microbiocenosis imbalance that enhances the effectiveness of early diagnosis of inflammatory periodontal diseases.

scholarly journals SOME ASPECTS OF THE EATIOLOGY OF PARODONTUS DISEASES. (LITERATURE REVIEW)

2018 ◽  
pp. 54-59
Author(s):  
N.N. Saveleva ◽  
I.I. Sokolova ◽  
S.I. German ◽  
T.V. Tomilina
Keyword(s):  
Gastrointestinal Tract ◽  
Periodontal Disease ◽  
Structural Damage ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Chronic Obstructive ◽  
Internal Organs ◽  
Periodontal Tissues

The review of the scientific literature is devoted to the topical issues of studying the etiology of periodontal diseases, which are one of the most common and complex pathologies of the maxillofacial region. Analysis of recent studies proves a stable relationship between the development of periodontal diseases and disorders in the immune system, the neurohumoral system, metabolic disorders, genetic predisposition, and so on. The article presents the data obtained in the course of studying the literature on the role of disorders in the functioning of individual organs (gastrointestinal tract, liver, lungs, heart, and urinary system) in the development of chronic periodontal diseases. The article notes that the anatomical and physiological proximity of the periodontal and digestive tract tissues, the generality of innervation and humoral regulation create prerequisites for the involvement of periodontal disease in the pathological process in diseases of the gastrointestinal tract. One of the main etiological factors in the development of inflammatory diseases of the gastrointestinal tract and periodontium is Helicobacter pylori, which is found in the loci of the oral cavity: in the oral and gingival fluid, on the mucous membrane of the tongue and cheeks, and in the periodontal pockets. It is pointed out that the liver also occupies a special place in the development of periodontal diseases, which is explained by the performance of its significant functions for the human body: regulatory, metabolic, antitoxic and other. There is evidence that the pathology of periodontal disease plays a leading role in the structure of dental diseases in patients with chronic obstructive pulmonary diseases, which is clinically manifested by symptoms of generalized periodontitis of the І-ІІ degrees of development and its complications - partial or complete secondary adentia, and with tooth preservation - defects in dental series and violations of occlusion, function, aesthetics. Scientists suggest a general biological mechanism for the development of generalized periodontitis and cardiovascular diseases, linking the development of periodontal diseases in patients with cardiovascular pathology with microcirculatory disorders. The dependence of the severity of inflammatory changes in the periodontal tissues on the disturbances of salt metabolism in urolithiasis is proved. The data obtained indicate that diseases of the internal organs contribute to the structural damage of periodontal tissues and they are a risk factor for periodontal diseases, which necessitate the presence of not only theoretical knowledge and practical skills in dentistry, but also their awareness of the features and clinical manifestations of somatic pathology. An urgent and justified step in the treatment of periodontal diseases is also the involvement in the process of rendering complex dental care to internist doctors capable of quickly and qualitatively assessment the condition of the internal organs and the basic systems of the patient's body.

scholarly journals CONDITIONS OF THE ORAL CAVITY STATUS IN YOUTH WITH ALIMENTARY-CONSTITUTIONAL FORM OF OBESITY

2019 ◽  
Vol 23 (1-2) ◽  
pp. 17-21
Author(s):  
M. Skrypnyk ◽  
T. Petrushanko ◽  
T. Kryvoruchko ◽  
K. Neporada
Keyword(s):  
Oral Cavity ◽  
Periodontal Disease ◽  
Periodontal Diseases ◽  
Young Patients ◽  
Overweight And Obesity ◽  
Obesity Prevalence ◽  
Periodontal Tissues ◽  
Mild Degree ◽  
Inflammatory Processes ◽  
Second Degree

Obesity prevalence has significantly increased especially in young adults, which is caused by a particular lifestyle, food quality and dietary behavior. Obesity leads to development of huge array of comorbid conditions such as arterial hypertonia, heart stroke, arthritis and other diseases. We conducted standard clinical examination of oral cavity of 154 young patients (18-21 years old) – all of them were students of Ukrainian Medical Stomatological Academy. It has been determined that the majority of patients with BMI >30 kg/cm2 have aggravated family heredity, in 66,2% cases one parent of obese students had obesity and 32,43% patients have both parents with obesity that is significantly higher compared with persons with normal BMI and overweight. There was a high prevalence of periodontal diseases about 74% and carious lesions of teeth - 97.4% among young people despite the age and contingent of examined patients - medical students. In patients with BMI >30 kg/cm2 prevalence of generalized forms of gingivitis and periodontitis was by three times higher compared with individuals with normal BMI. The values of oral hygienic indexes were poor in all examined groups, but their values were slightly lower in patients with normal BMI than in those with overweight and obesity. The prevalence of inflammatory changes in gums was higher in persons with obesity: all of them had a mild degree of lesions in periodontal tissues. Inflammatory processes in the gums were the most intense in patients with the second degree of obesity. According to the results of the study, the presence of the first and the second degree of obesity should be considered as a risk factor triggering periodontal tissues diseases. For persons with BMI >30 kg/cm2 with periodontal disease measures for the secondary prevention of inflammatory and inflammatory dystrophic periodontal diseases should be carried out and in persons without periodontal disease on the background of obesity measures primary prevention should be done.

scholarly journals Comparative evaluation of expression of VEGF (vascular endothelial growth factors) in periodontal tissues of healthy, chronic and aggressive periodontitis patients: an immunohistochemical study

2020 ◽  
Vol 9 (1) ◽  
pp. 784-788
Keyword(s):  
Growth Factors ◽  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Control Group ◽  
Vascular Endothelial ◽  
Healthy Controls ◽  
Periodontal Tissues ◽  
Inflammatory Status

Periodontitis is a chronic inflammatory disease of the vascularized supporting tissues of the teeth. Angiogenesis (neovascularization) is the budding of new capillaries and is thought to be an essential process in the development of chronic inflammatory diseases. Inflamed tissues (such as gingiva coincident in periodontal disease) have evidence of enhanced expression of inflammatory mediators, many of which can promote angiogenesis. Of the various cytokines and growth factors that are involved in angiogenesis, the most potent agent that acts specifically on vascular epithelium is Vascular Endothelial Growth Factor. Even though angiogenesis is a prominent feature of both inflammation and healing, information about its role in periodontal lesions is limited. Hence the aim of the present study was the immunohistochemical evaluation of the expression of VEGF in the gingival tissues of chronic and aggressive periodontitis patients compared to the healthy controls. The present study was carried out in a total of 45 subjects with age range of 18-55 years, reporting to the Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore. Gingival tissue samples were collected from all the 45 subjects and categorized into three groups based on their clinical findings as follows: Group 1 (Healthy), Group II (Chronic Periodontitis), Group III (Aggressive Periodontitis). Following sample collection, immunohistochemical staining of tissues was carried out and evaluation was done to compare the grades of expression of VEGF in the three groups. The expression of VEGF in blood vessels was also quantitatively evaluated. The results were statistically analyzed using Kruskal Wallis ANOVA and Mann Whitney test. There was a statistically significant higher expression of VEGF in both chronic periodontitis and aggressive periodontitis group as compared to the control group. Aggressive periodontitis cases showed higher grades of expression of VEGF compared to the chronic periodontitis cases and healthy controls. However, the difference in expression of VEGF was not statistically significant between the two forms of periodontitis. The presence of VEGF in both chronic and aggressive periodontitis clearly indicates the potent role played by VEGF as an inflammatory agent in the initiation and progression of periodontal diseases. Thus, VEGF might be used as a potential vascular marker for the assessment of severity and inflammatory status in periodontal disease.

scholarly journals MICRO BIOLOGY OF PERIODONTAL DISEASE- A REVIEW

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Jageer Chinna ◽  
Jannat Sharma
Keyword(s):  
Periodontal Disease ◽  
Periodontal Diseases ◽  
Disease Process ◽  
Fusobacterium Nucleatum ◽  
Host Cells ◽  
Bacterial Invasion ◽  
Periodontal Pathogens ◽  
Tissue Destruction ◽  
Campylobacter Rectus ◽  
Periodontal Tissues

Periodontal diseases are inflammatory and destructive diseases of the dentogingival complex associated with specific periodontal pathogens inhabiting periodontal pockets. Periodontal diseases lead to damage of the periodontal tissues supporting the teeth (bone and connective tissue) and affect the quality of life of the affected individuals: poor alimentation, tooth loss, social and financial problems. Although it is generally considered that the disease has multifactorial etiology, data show that some specific Gram-negative microorganisms in the subgingival plaque biofilm play a major role in the initiation and progression of periodontitis. Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia form a consortium in the subgingival biofilm and are regarded as the principal periodontopathogenic bacteria. Other microorganisms that have been implicated as predominant species in the disease process are: Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Campylobacter rectus, Peptostreptococcus migros, Eikenella corrodens. In periodontitis, the initiation of the disease is the colonization of the tissues by these pathogenic species. The next step is bacterial invasion or invasion by pathogenic products into the periodontal tissues, interactions of bacteria or their substances with host cells, and this directly/indirectly causes degradation of the periodontium, resulting in tissue destruction. Keywords: periodontal disease, periodontal pathogens, microbiology.

scholarly journals CHARACTERISTICS OF THE COMPOSITION OF GINGIVAL POCKETS MICRFLORA ISOLATED FROM PATIENTS WITH PURULENT INFLAMMATORY DISEASES IN THE PERIODONTAL TISSUES

2021 ◽  
pp. 20-26
Author(s):  
I. A. Voronkina ◽  
V. F. Dyachenko ◽  
A. M. Maryuschenko ◽  
E. S. Serdechna ◽  
V. G. Rusanova
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Disease Incidence ◽  
Specific Weight ◽  
Biochemical Properties ◽  
World Health ◽  
Candida Spp ◽  
Isolation And Identification ◽  
Periodontal Tissues ◽  
Staphylococcus Spp

The problem of the purulent inflammatory disorders of periodontal tissues (PIDPT) at the present time is extremely prevalent. According to the World Health Organization (WHO), around 80% of people suffer from periodontal diseases, and the disease incidence among young people increases significantly and reaches up to 80-95 %. The aim of the present research was to study the composition of microflora of gingival pockets in patients with purulent inflammatory periodontal diseases (PIDPT) in order to establish the specific weight of the determined microbial associations. Materials and methods. Microbiological researches included isolation and identification of bacteria that were present in the gingival pockets of patients with different types of PIDPT. Identification of anaerobic microorganisms and associated microflora was carried out with the help of commonly used classical bacteriological methods, with determination of biochemical properties of the microorganisms cultures using APІ and ANAEROtest 23. Results. There were 192 patients studied in total, all aged older than 20 with diagnoses acute and chronical periodontitis, aggressive periodontitis, hypertrophic pulpitis, granulating periodontitis, parodontopathy, and local periodontitis with a presence of fistula. During the analysis of composition of the microflora isolated from periodontal tissue in patients with PIDPT, the following pathogens were isolated most frequently during the bacteriological research: Streptococcus spp., Staphylococcus spp., Neisseria spp., Stomatococcus spp., and Enterococcus spp. (58%). The quantity of periodontally pathogenic microorganisms was constituted 19,3% from the total quantity of isolated streains (81 isolates). The most numerous group was determined to be the “orange” complex (59,3%) – isolates of Prevotella melaninogenica, Fusobacterium nucleatum, Parvimonas micra. The least numerous was the group of “green” complex - (2,5 %) – Streptococcus mitis. Periodontally pathogenic representatives of microbiota in all cases were isolated as a part of associations with other bacteria. The presented materials signified that the periodontally pathogenic agents of the “red” and “orange” complexes were isolated together with representatives of Streptococcus spp - 33 (56,0 %) associations; Staphylococcus spp - 11(18,6%) – associations. Also in 13 cases (22,1 %) of associations the associated flora was represented by Candida spp. fungi. Conclusions. In course of the research, 4 species of “red” and “orange” complexes were identified, and the quantity of different associations there were present in was significant. There were 22 associations determined. The obtained date concerning microbial associates in the content of gingival pockets in PIDPT show the necessity of individual approach during treatent of this patient group, with taking into account the microbial diversity.

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