Theoretical and practical data on the use of mud in conjunction with some types of electrotherapy

1929 ◽  
Vol 25 (5) ◽  
pp. 574-574
Author(s):  
L. N. Klyachkin
Keyword(s):  
Spinal Cord ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Clinical Picture ◽  
Therapeutic Success ◽  
Radicular Symptom ◽  
Combined Use ◽  
Symptom Complex

SD Bassel (Kl. Med., 6, 1929) believes that the therapeutic success of mud cakes can be increased by the combined use of certain types of electrotherapy, which is feasible in an out-of-resort setting. Favorable results are obtained with skin scars and diseases of individual joints, as well as with forms of diseases of the spinal cord, where the meningeal-radicular symptom complex predominates in the clinical picture. Favorable results in a number of diseases of the peripheral nervous system

scholarly journals The neuropathology of “typical” Friedreich's ataxia in Quebec

1984 ◽  
Vol 11 (S4) ◽  
pp. 592-600 ◽  
Author(s):  
J.B. Lamarche ◽  
B. Lemieux ◽  
H.B. Lieu
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Diagnostic Criteria ◽  
Clinical Findings ◽  
Spinal Ganglia ◽  
Cooperative Study ◽  
Segmental Demyelination ◽  
Dying Back

AbstractWe present the pathological data from the autopsies performed on 6 Friedreich's disease patients since the start of the Quebec Cooperative Study. All patients met the strict diagnostic criteria of the QCSFA. The anatomical lesions found in the peripheral and central nervous system were similar in all 6 cases and do not differ from those described in the literature. The clinical findings correlate closely with the histological lesions found in the peripheral nervous system and spinal cord. The evidence of segmental demyelination and remyelination in the spinal ganglia and posterior roots further supports the dying-back axonopathy hypothesis.

Neurological aspects of spinal disorders in children

2011 ◽  
Author(s):  
Najma Farooq ◽  
S.K. Tucker ◽  
D. Thompson
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Clinical Picture ◽  
Spinal Disorders ◽  
Central Nervous System Tumours ◽  
Urological Symptoms ◽  
Systemic Disorder ◽  
Intradural Extramedullary

♦ Spinal neurological problems may be a focal anomaly or part of a systemic disorder♦ The neuro-orthopaedic syndrome should be considered in any dysraphic patient with a changing clinical picture—urological symptoms respond well to prompt untethering♦ Ten per cent of central nervous system tumours originate in the spinal cord—they may be intramedullary, intradural extramedullary, or extradural.

scholarly journals Sampling and Evaluating the Peripheral Nervous System

2019 ◽  
Vol 48 (1) ◽  
pp. 10-18 ◽  
Author(s):  
Mark T. Butt
Keyword(s):  
Spinal Cord ◽  
Nervous System ◽  
Sciatic Nerve ◽  
Peripheral Nervous System ◽  
Morphological Changes ◽  
Sampling Strategy ◽  
Mechanisms Of Toxicity ◽  
Test Article ◽  
Ganglion Neurons ◽  
The Brain

Many preclinical investigations limit the evaluation of the peripheral nervous system (PNS) to paraffin-embedded sections/hematoxylin and eosin–stained sections of the sciatic nerve. This limitation ignores several key mechanisms of toxicity and anatomic differences that may interfere with an accurate assessment of test article effects on the neurons/neurites peripheral to the brain and spinal cord. Ganglion neurons may be exposed to higher concentrations of the test article as compared to neurons in the brain or spinal cord due to differences in capillary permeability. Many peripheral neuropathies are length-dependent, meaning distal nerves may show morphological changes before they are evident in the mid-sciatic nerve. Paraffin-embedded nerves are not optimal to assess myelin changes, notably those leading to demyelination. Differentiating between axonal or myelin degeneration may not be possible from the examination of paraffin-embedded sections. A sampling strategy more consistent with known mechanisms of toxicity, atraumatic harvest of tissues, optimized fixation, and the use of resin and paraffin-embedded sections will greatly enhance the pathologist’s ability to observe and characterize effects in the PNS.

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