Cholinergic variant of infectious allergic bronchial asthma

1986 ◽  
Vol 67 (5) ◽  
pp. 352-354
Author(s):  
A. D. Ado ◽  
R. M. Zolotareva

Infectious and allergic bronchial asthma occurs on the basis of inflammatory diseases: acute and chronic pneumonia, influenza, bronchitis, pathology of ENT organs. Bacteria, toxins, decay products of own tissues cause sensitization process and subsequent allergic reaction, which is localized in the tissues of the bronchial tree, involves primarily the peripheral structures of the autonomic nervous system and can cause increased excitability of the parasympathetic department.

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 65
Author(s):  
Athanasios Beopoulos ◽  
Manuel Gea ◽  
Alessio Fasano ◽  
François Iris

Dysbiosis secondary to environmental factors, including dietary patterns, antibiotics use, pollution exposure, and other lifestyle factors, has been associated to many non-infective chronic inflammatory diseases. Autism spectrum disorder (ASD) is related to maternal inflammation, although there is no conclusive evidence that affected individuals suffer from systemic low-grade inflammation as in many psychological and psychiatric diseases. However, neuro-inflammation and neuro–immune abnormalities are observed within ASD-affected individuals. Rebalancing human gut microbiota to treat disease has been widely investigated with inconclusive and contradictory findings. These observations strongly suggest that the forms of dysbiosis encountered in ASD-affected individuals could also originate from autonomic nervous system (ANS) functioning abnormalities, a common neuro–anatomical alteration underlying ASD. According to this hypothesis, overactivation of the sympathetic branch of the ANS, due to the fact of an ASD-specific parasympathetic activity deficit, induces deregulation of the gut–brain axis, attenuating intestinal immune and osmotic homeostasis. This sets-up a dysbiotic state, that gives rise to immune and osmotic dysregulation, maintaining dysbiosis in a vicious cycle. Here, we explore the mechanisms whereby ANS imbalances could lead to alterations in intestinal microbiome–host interactions that may contribute to the severity of ASD by maintaining the brain–gut axis pathways in a dysregulated state.


2021 ◽  
Vol 12 (2) ◽  
pp. 13-18
Author(s):  
Vladimir N. Buryak ◽  
Tatyana I. Antonova ◽  
Maria V. Dudko ◽  
Inna V. Malysheva ◽  
Kirill K. Shepelenko

Background. In most industrialized countries, allergic diseases affect up to 20% of the population. This pathology belongs to the most common in children: according to the World Health Organization, more than 15% of the world's child population suffers from it. In recent years, there has been a significant increase in the frequency and more severe course of these diseases, in connection with which they are considered in modern society as a major medical and social problem. Thus, the prevalence of bronchial asthma, according to domestic and foreign authors, ranges from 0.2 to 8.1%. Purpose. In order to clarify the role of the autonomic nervous system in the genesis of the mild course of atopic bronchial asthma in childhood, the features of the interaction of the sympathetic and parasympathetic divisions of the autonomic nervous system in the examined children were clarified. Materials and methods. 126 children aged 10 to 14 years were examined. Atopic bronchial asthma was diagnosed in 91 children. At the same time, 61 of them were diagnosed with an intermittent course, 30 a mild persistent course of the disease. The control group consisted of 35 healthy children also aged 10 to 14 years. Complaints, anamnesis data were studied in all children, an objective and generally accepted laboratory and instrumental examination was carried out. All examined children underwent daily monitoring of the electrocardiogram, according to the results of which, based on the analysis of time and frequency indicators of heart rate variability, a variant of the initial autonomic tone was established. Results. In children with atopic bronchial asthma, both with intermittent and mild persistent course, an absolute or relative dominance of sympathetic influences was revealed against the background of varying degrees of decrease in parasympathetic activity, which was interpreted as a compensatory reaction of the body in response to chronic allergic inflammation.


2016 ◽  
pp. 122-124
Author(s):  
H. K. Honkeldieva ◽  
I. I. Alimdzhanov ◽  
М. E. Abdullaeva ◽  
T. T. Tojiboev ◽  
M. S. Mamatkhyjaev

2016 ◽  
pp. 122-124
Author(s):  
H. K. Honkeldieva ◽  
I. I. Alimdzhanov ◽  
М. E. Abdullaeva ◽  
T. T. Tojiboev ◽  
M. S. Mamatkhyjaev

2021 ◽  
pp. 71-82
Author(s):  
Natalya Anatolievna Lyan ◽  
Maya Alekseevna Khan ◽  
Marina Anatolievna Rassulova ◽  
Irina Ivanovna Ivanova ◽  
Irina Anatolievna Bokova

Review purpose: the presentation of modern technologies of medical rehabilitation of children with bronchial asthma. Basic provisions: Recently, the increasing significance is attached to non-drug methods of treatment of bronchial asthma owing to the high frequency of undesirable effects when using medicinal preparations. The main objectives of medical rehabilitation in bronchial asthma are normalizing respiratory function, rendering anti-inflammatory and anti-edematous effect on bronchial mucosa, normalizing the state of the central and autonomic nervous system, increasing tolerance to an exercise stress, and strengthening protective forces of an organism. Conclusion: The treatment of children with bronchial asthma with the use of non-drug technologies is applied at all stages of medical rehabilitation.


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