scholarly journals Intensive treatment in observing pregnant women with Rh-isoimmunization

2003 ◽  
Vol 52 (1) ◽  
pp. 55-60
Author(s):  
Eduard K. Ailamazyan

Diagnosis and treatment of hemolytic disease of fetus is one of the urgent problems of contemporary obstetrics. This article reveals the cause and pathophysiologic basis of its development. It shows steps in observing pregnant women with Rh-immunization, determines criteria of severity of hemolytic disease. One can find indications for intra-uterine transfusion of donor's erythrocytes.

2018 ◽  
Vol 25 (4) ◽  
pp. 102-105
Author(s):  
O. V. TURICHENKO ◽  
E. E. KORCHAGINA ◽  
A. A. LAPIN

Aim. The aim of the study is to evaluate the effectiveness of the modern methods of prenatal diagnosis and treatment of hemolytic  disease of the fetus based on the analysis of researchers’ own clinical material accumulated during 12 years.Materials and methods. There was performed a prospective analysis of 210 pregnant women with RH-immunization with noninvasive methods of diagnosis and invasive methods of  treatment of HDF. Also there was conducted the analysis of the introduction of the specialized reception and monitoring of the  maximum systolic circulation rate (MSCR) increase in the middle cerebral artery (MCA) in the diagnosis of anemia of the fetus.Results. The specialized reception of pregnant women with RH-immunization organized at the Perinatal Center in 2005 allowed us to carry out timely diagnostics of the anemic syndrome in the fetus and  made it possible to start the prenatal treatment primarily at the moderate severity stage of anemia. Pregnant women with the  edematous form of HDF entered the PC either with an established  diagnosis or it was determined during the first appointment at the PC.Conclusion. As a result, we proved the effectiveness of the intrauterine treatment of severe forms of anemia in the fetus and showed the effectiveness of such tactics of management of pregnant women with RH-immunization.


2017 ◽  
pp. 84-87
Author(s):  
O.V. Islamova ◽  

The main data on general issues of epidemiology, etiology, pathogenesis and classification of chronic glomerulonephritis (CGN) in Ukraine were described in the article. The main information on the peculiarities of this clinic disease in pregnant women, on the course and complications of pregnancy, features of fetal development in pregnant women suffering from chronic pyelonephritis were highlighted. Separately, the questions devoted to the optimal tactics of diagnosis and treatment of CGN in pregnant women with characteristics of medicines and their groups applicable in this category of patients are disclosed. The rules for management of pregnancy, delivery and postpartum period are described. Key words: сhronic glomerulonephritis, pregnancy, treatment.


Cureus ◽  
2020 ◽  
Author(s):  
Suman S Routray ◽  
Jagdish P Sahoo ◽  
Rachita Behera ◽  
Devi Acharya ◽  
Girija N Kanungo

2020 ◽  
Vol 232 (06) ◽  
pp. 314-320
Author(s):  
Marjana Jerkovic Raguz ◽  
Zeljka Prce ◽  
Vedran Bjelanovic ◽  
Ivana Bjelanovic ◽  
Sanja Dzida ◽  
...  

Abstract Objective of the study is to research the epidemiological aspects of maternal alloimmunization against erythrocyte antigens of fetuses (AB0, Rhesus, Lewis, Kell, Duffy and others) and to identify the most common types of hemolytic disease of the newborn (HDN) in the West Herzegovina region. Study Design The 20-year retrospective epidemiological study includes all pregnant women who had been immunologically tested and newborn treated for HDN. Results The indirect antiglobulin (IAT) detected antibodies against antigens in 545 (1.8%) pregnant women of the 29 663 who were tested at the Department of Transfusion Medicine. During the 20-year-long study 310 (1.0%) newborn with HDN were treated. Our results indicate that 42% (230/545) of the pregnant women had AB0 immunization. The most common form of HDN is AB0 HDN 64% (199/310), whereas RhD HDN was treated in 19% (59/310) of the newborn infants. ETR was performed on 29 (19%) infants, 21 (72.4%) with AB0 HDN, and 7 (26%) with RhD HDN. Conclusion This 20-year-long study concludes that, even though there has been significant progress in the prevention of immunization and proactive treatment of HDN, precautionary measures are still required as is the need for gynecologists and obstetricians to be active. The reasons for this are the non-existence of preventive measures for non-RhD immunization, the irregular immunological screening of RhD positive women in pregnancy in the region encompassed by the study in the past few years. The above raises new questions and recommends further research and monitoring of immunization and HDN treatment worldwide.


Parasitology ◽  
2019 ◽  
Vol 147 (2) ◽  
pp. 127-134
Author(s):  
Oyetunde T. Oyeyemi ◽  
Ifeoluwa T. Oyeyemi ◽  
Isaac A. Adesina ◽  
Adebisi M. Tiamiyu ◽  
Yinka D. Oluwafemi ◽  
...  

AbstractToxoplasmosis is a global health threat in which occurrence in pregnant women poses grave consequences to fetal wellbeing. Studies on prenatal Toxoplasma gondii infection are generally limited in sub-Saharan African countries, including Nigeria. The risk of transmission of toxoplasmosis is very high in Nigeria due to the favourable climatic conditions and prevailing behavioural and socio-economic factors that could aid transmission. Currently, there are no systematic and organized procedures for diagnosis and treatment of maternal toxoplasmosis in Nigeria. These conditions forecast possible unabated transmission in many areas and exponential impact on associated adverse events of the disease during pregnancy. This paper highlights the importance of early diagnosis and treatment during pregnancy which may forestall subsequent development of infection in children delivered by infected mothers. Inclusion of toxoplasmosis control policy in the routine antenatal care of pregnant women is therefore strongly recommended.


Blood ◽  
1950 ◽  
Vol 5 (8) ◽  
pp. 767-772 ◽  
Author(s):  
S. P. LUCIA ◽  
MARJORIE L. HUNT

Abstract 1. A series of 1337 obstetric cases, of which 170 were instances of sensitized Rh negative women, were studied with regard to (a) the incidence of the ABO blood groups, and (b) the incidence of ABO compatibility between the mother and child. 2. The incidence of ABO compatibility between the mother and child was found to vary with the blood group of the mother. 3. ABO compatibility between the mother and child was found to be present in 80 per cent of an unselected obstetric population in contrast to 95 per cent in a group of sensitized Rh negative women who bore infants afflicted with hemolytic disease of the newborn. 4. ABO compatibility appears to be related to the occurrence of hemolytic disease of the newborn. 5. In 120 sensitized Rh negative women who bore afflicted infants, the incidence of group A mothers was greater than expected.


2018 ◽  
Vol 11_2018 ◽  
pp. 146-151
Author(s):  
Gadzhieva Z.K. Gadzhieva ◽  
Gomberg M.A. Gomberg ◽  
Grigoryan V.A. Grigoryan ◽  
Gazimiev M.A. Gazimiev ◽  
Kazilov Yu.B. Kazilov ◽  
...  

2009 ◽  
Vol 5 (3) ◽  
pp. 263-268
Author(s):  
Robert Fraser

After many years of uncertainty regarding the true pathological nature of mild gestational diabetes and the possible benefits of treatment, the situation appears to have been resolved by the publication of the Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS). It is now appropriate for obstetric units to review their treatment and screening programs for gestational diabetes mellitus. Furthermore, with the publication of the Metformin in Gestational Diabetes (MiG) trial, consideration should be given as to whether metformin should be the first choice when diet fails to maintain glycemic control.


2018 ◽  
Vol 85 (6) ◽  
pp. 13-17
Author(s):  
Ya. P. Feleshtynskyi ◽  
О. V. Golyanovskyi ◽  
Т. P. Pavliv

Objective. Improvement of the treatment results of an acute pancreatitis in pregnant women, using enhanced early diagnosis and tactics of treatment. Маterials and methods. Analysis of the diagnosis and treatment results was conducted in 123 pregnant women, suffering an acute pancreatitis. In the main group (61 pregnant women) the elaborated algorithm of diagnosis and treatment for an acute pancreatitis in the period 2012 - 2018 yrs was applied, while in a comparison group (62 pregnant women) - the standard methods of diagnosis and treatment in an acute pancreatitis for the period of 2006 - 2012 yrs. Results. In the main group in 100% of the patients an acute pancreatitis was revealed on early stage. This have had guaranteed the effect obtaining from the conservative therapy in 27 (44.3%) pregnant women, using miniinvasive surgical interventions - in 31 (50.8%) and to prevent postoperative lethality. In a comparison group in 26 (41.9%) patients an acute pancreatitis diagnosis was established in (8 ± 2.1) days after the disease beginning. In a comparison group the conservative treatment effect was observed in 21 (33.9%) patients only. Two (3.2%) pregnant women died. Conclusion. Application of the diagnostic-treatment algorithm, comparing with standard methods, permits to diagnose an acute pancreatitis in pregnant women on early stage, to reduce the complications and lethality rate.


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