scholarly journals Clinical and diagnostic criteria of cholestatic hepatosis severity in pregnancy

2015 ◽  
Vol 64 (2) ◽  
pp. 25-32
Author(s):  
Natal’ya Vladimirovna Zhestkova ◽  
Valeriy Grigor’yevich Radchenko ◽  
Zhanna Nikolaevna Tumasova
Keyword(s):  
Alkaline Phosphatase ◽  
Diagnostic Criteria ◽  
Pregnancy Loss ◽  
Placental Insufficiency ◽  
Fetal Hypoxia ◽  
Cholesterol Levels ◽  
Pregnancy And Delivery ◽  
In Pregnancy

The function condition of hepatobiliar system was investigaited in 120 pregnant with cholestatic hepatosis. The main criteria of cholestatic hepatosis severity were skin itching accompanied with increasing of biliar acids levels, transaminazes activities, alkaline phosphatase and cholesterol levels. Based on clinical and laboratory dates the outcomes of pregnancy and delivery were analysed. There were revealed that pregnancy loss, gestosis, placental insufficiency, IUGR and fetal hypoxia were met more often in groups with middle- and high severe cholestatic hepatosis.

scholarly journals Gestation in patients with a combination of antiphospholipid and torch syndromes

2021 ◽  
Vol 6 (2) ◽  
pp. 41-50
Author(s):  
E. N. Kravchenko ◽  
A. A. Goncharova
Keyword(s):  
Pregnant Women ◽  
Medical Records ◽  
Pregnancy Loss ◽  
Preconception Care ◽  
First Trimester ◽  
Placental Insufficiency ◽  
Control Group ◽  
Fetal Hypoxia ◽  
History Of ◽  
Threatened Abortion

Aim. To study the features of gestation in women with a combination of antiphospholipid and TORCH syndromes in relation to preconception care.Materials and Methods. We analyzed 137 medical records of women with a past medical history of pregnancy loss and antiphospholipid syndrome (APS), focusing on the presence or absence of plasmapheresis in the preconception period, and further ranking the patients into 2 subgroups (with and without TORCH syndrome). As a control group, we included 28 pregnant women without both syndromes.Results. Gestation in women with combined APS and TORCH syndromes was accompanied by a 10-fold higher risk of threatened abortion in the first trimester and 3-fold higher risk of placental insufficiency as compared to those without both syndromes. Notably, the combination of the syndromes doubled the risk of placental insufficiency in comparison with APS alone. The lack of plasmapheresis in patients with APS and TORCH syndrome was associated with > 2-fold higher risk of threatened abortion. Further, in patients with APS and TORCH syndrome, lack of plasmapheresis increased the likelihood of developing fetal hypoxia by a factor of 2 and 3 in comparison with those diagnosed with APS alone or control patients.Conclusions. TORCH syndrome is a major risk factor of adverse outcome in pregnant women with APS. Inclusion of plasmapheresis into the preconception care in women with APS and TORCH syndrome significantly reduced the development of pregnancy complications. 

scholarly journals Protein S and pregnancy: Report of a case

2002 ◽  
Vol 130 (1-2) ◽  
pp. 36-37
Author(s):  
Radica Dunjic ◽  
Ivo Elezovic ◽  
Snezana Rakic ◽  
Zeljko Mikovic ◽  
Helena Loncar-Stevanovic
Keyword(s):  
Anticoagulant Therapy ◽  
Pregnancy Loss ◽  
Protein S ◽  
Functional Protein ◽  
The Third ◽  
Low Protein ◽  
Pregnancy And Delivery ◽  
In Pregnancy

Protein S is a cofactor of protein S which lowers the activat- ed factors VIII and V. Pregnancy reduces the level of protein S to 40-50% of normal levels but it is not clear whether the lowered protein S levels increase the risk of developing thrombo-embolism during pregnancy. This is a report of a 39-year old woman, multipart whose pregnancy terminated as IUGR and who had previously two stillbirths. After the third pregnancy loss of functional protein S level was 20%. Two months after delivery protein S activity was 60%. As it was suspected that low protein S level was a risk factor of complications in pregnancy anticoagulant therapy was used. Thereafter pregnancy and delivery at 38.5 weeks of gestation were successful and the baby weighted 3400 gr at birth. The aim of this report is to emphasize the important role of follow-up of the level of protein S in pregnancy in order to avoid the risk of thrombo-embolism in pregnancy. Anticoagulant therapy is very successful in such a pregnancy and may ensure safe birth.

LEUCOCYTE METABOLISM IN PREGNANCY

1960 ◽  
Vol XXXV (IV) ◽  
pp. 575-584 ◽  
Author(s):  
C. Borel ◽  
J. Frei ◽  
A. Vannotti
Keyword(s):  
Alkaline Phosphatase ◽  
Oxygen Consumption ◽  
Pregnant Women ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Lactate Production ◽  
Glucose Consumption ◽  
In Pregnancy

ABSTRACT Enzymatic studies, on leucocytes of pregnant women, show an increase of the alkaline phosphatase activity and a decrease of the glucose consumption and lactate production, as well as of proteolysis. The oxygen consumption, with succinate as substrate, does not vary.

P-006 Polymorphisms of placental alkaline phosphatase gene are associated with recurrent pregnancy loss

2013 ◽  
Vol 131 ◽  
pp. S78
Author(s):  
S. Bouvier ◽  
M. Vatin ◽  
L. Bellazi ◽  
X. Montagutelli ◽  
P. Laissue ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Placental Alkaline Phosphatase

Leukocyte alkaline phosphatase in pregnancy and the puerperium

1970 ◽  
Vol 107 (4) ◽  
pp. 604-609 ◽  
Author(s):  
W.Z. Polishuk ◽  
Y.Z. Diamant ◽  
H. Zuckerman ◽  
E. Sadovsky
Keyword(s):  
Alkaline Phosphatase ◽  
Leukocyte Alkaline Phosphatase ◽  
In Pregnancy

Placental pathology in pregnancy loss

Placenta ◽  
2021 ◽  
Vol 103 ◽  
pp. 256
Author(s):  
Daisuke Fujita ◽  
Misa Nunode ◽  
Masami Sawada ◽  
Yoko Nagayasu ◽  
Takumi Sano ◽  
...  
Keyword(s):  
Pregnancy Loss ◽  
Placental Pathology ◽  
In Pregnancy

Miscarriage After Noninvasive Prenatal Screening—The Value of Genetic Testing in Pregnancy Loss [34J]

2018 ◽  
Vol 131 ◽  
pp. 117S
Author(s):  
Melissa Maisenbacher ◽  
Wendy DiNonno ◽  
Katrina Merrion ◽  
Michael Young ◽  
Styrmir Sigurjonsson ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Pregnancy Loss ◽  
Prenatal Screening ◽  
Noninvasive Prenatal Screening ◽  
In Pregnancy

scholarly journals The Effect of HSV-1 Seropositivity on the Course of Pregnancy, Childbirth and the Condition of Newborns

2022 ◽  
Vol 10 (1) ◽  
pp. 176
Author(s):  
Irina Anatolyevna Andrievskaya ◽  
Irina Valentinovna Zhukovets ◽  
Inna Victorovna Dovzhikova ◽  
Nataliya Alexandrovna Ishutina ◽  
Ksenia Konstantinovna Petrova
Keyword(s):  
Neonatal Period ◽  
Recurrent Infection ◽  
First Trimester ◽  
Placental Insufficiency ◽  
Igg Antibodies ◽  
Pregnancy And Childbirth ◽  
Serological Status ◽  
Anemia In Pregnancy ◽  
In Pregnancy ◽  
Hsv 1

The goal of this research was to evaluate seropositivity to HSV-1 among pregnant women and its effect on the course of pregnancy, childbirth and the condition of newborns. Methods: The serological status, socio-demographic characteristics, parity of pregnancy and childbirth and condition of newborns in women seronegative and seropositive to HSV-1 with recurrent infection and its latent course during pregnancy were analyzed. Newborns from these mothers made up the corresponding groups. Results: Low titers of IgG antibodies to HSV-1 in women in the first trimester of pregnancy are associated with threatened miscarriage, anemia in pregnancy and chronic placental insufficiency. High titers of IgG antibodies to HSV-1 in women in the second trimester of pregnancy are associated with late miscarriages and premature births, anemia in pregnancy, chronic placental insufficiency, labor anomalies, early neonatal complications (cerebral ischemia, respiratory distress syndrome) and localized skin rashes. Low titers of IgG antibodies to HSV-1 in women in the third trimester of pregnancy are associated with premature birth, anemia in pregnancy, chronic placental insufficiency, endometritis, complications of the early neonatal period and localized skin rashes. Conclusions: Our research showed that low or high titers of IgG antibodies to HSV-1, determined by the timing of recurrence of infection during pregnancy, are associated with a high incidence of somatic pathology and complications in pregnancy, childbirth and the neonatal period.

Sign in / Sign up

Export Citation Format

Share Document