scholarly journals Mechanisms of Modificational Variability

2007 ◽  
Vol 5 (1) ◽  
pp. 21-24
Author(s):  
Sergey G Inge-Vechtomov

Types of modifications and their position within the traditional classification of variability are analyzed. Through this approach contradictory status of the classification based upon phenomenology of variability is demonstrated. Interdependency of modifications and of inherent variability permits to pose an alternative classification of variability, based upon its mechanisms. There are variability: (1) connected with storage of genetic information and with replication of its carriers (genetic material) and (2) connected with realization (expression) of genetic information. So, it follows that idea of inherent and non-inherent variability is a secondary one toward their mechanisms and are connected with the taxonomy and life cycle stages. of the biological objects under investigation.

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Charles McCartan ◽  
Robert Mason ◽  
S. R. Jayasinghe ◽  
Lyn R. Griffiths

Cardiomyopathies represent a group of diseases of the myocardium of the heart and include diseases both primarily of the cardiac muscle and systemic diseases leading to adverse effects on the heart muscle size, shape, and function. Traditionally cardiomyopathies were defined according to phenotypical appearance. Now, as our understanding of the pathophysiology of the different entities classified under each of the different phenotypes improves and our knowledge of the molecular and genetic basis for these entities progresses, the traditional classifications seem oversimplistic and do not reflect current understanding of this myriad of diseases and disease processes. Although our knowledge of the exact basis of many of the disease processes of cardiomyopathies is still in its infancy, it is important to have a classification system that has the ability to incorporate the coming tide of molecular and genetic information. This paper discusses how the traditional classification of cardiomyopathies based on morphology has evolved due to rapid advances in our understanding of the genetic and molecular basis for many of these clinical entities.


Author(s):  
Ramana V. Vadarevu ◽  
Peter R. Stopher

Four basic hypotheses about activities that are fundamental to pursuing an activity-based travel-forecasting modeling procedure are presented. They include classifying activities as mandatory, flexible, or optional; using life-cycle stages to differentiate the amount of time spent on different activities; determining whether there are differences in proportionate amounts of time spent on activities by gender; and examining role allocations to activities between people in a household on the basis of working status and gender. The hypotheses are tested by using a subsample of households from a sample collected in Boston in 1991 from an activity diary. Within the limitations of the data, it is found that the classification of activities appears to be sensible, and statistically significant differences are found among life-cycle groups. Differences are also found by gender and working status. Recommendations are made for further research and on some of the implications of these findings for activity modeling.


Author(s):  
Petar Halachev ◽  
Victoria Radeva ◽  
Albena Nikiforova ◽  
Miglena Veneva

This report is dedicated to the role of the web site as an important tool for presenting business on the Internet. Classification of site types has been made in terms of their application in the business and the types of structures in their construction. The Models of the Life Cycle for designing business websites are analyzed and are outlined their strengths and weaknesses. The stages in the design, construction, commissioning, and maintenance of a business website are distinguished and the activities and requirements of each stage are specified.


2019 ◽  
Vol 0 (3) ◽  
pp. 53-60 ◽  
Author(s):  
T.Yu. Altufyeva ◽  
◽  
P.A. Ivanov ◽  
G.R. Sakhapova ◽  
◽  
...  

2009 ◽  
Vol 66 (1) ◽  
Author(s):  
Susana Gómez-González ◽  
Lohengrin A Cavieres ◽  
Patricio Torres ◽  
Cristian Torres-Díaz

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