scholarly journals Photo gallery: Lichen planus

2020 ◽  
Vol 23 (5) ◽  
pp. 356-360
Author(s):  
O. Yu. Olisova ◽  
N. P. Teplyuk ◽  
O. V. Grabovskaya ◽  
Yuliya V. Kolesova
Keyword(s):  
Differential Diagnosis ◽  
Lichen Planus ◽  
Inflammatory Disease ◽  
Chronic Inflammatory Disease ◽  
Clinical Forms

Lichen planus (LP) is a chronic inflammatory disease of skin and mucous from group of papular dermatosis, less often affecting nails and hair. The article presents photographs of patients with various clinical forms of LP for a more thorough differential diagnosis of this disease.

scholarly journals Lichen Planus as a Possible Rare Cause of an Ocular Disease

2019 ◽  
Vol 75 (4) ◽  
pp. 219-223
Author(s):  
Jana Nekolová ◽  
Markéta Středová ◽  
Miroslav Podhola ◽  
Naďa Jirásková
Keyword(s):  
Lichen Planus ◽  
Inflammatory Disease ◽  
Ocular Surface ◽  
Negative Impact ◽  
Rare Event ◽  
Chronic Inflammatory Disease ◽  
Mental Condition ◽  
Unknown Etiology ◽  
Ocular Involvement ◽  
Irreversible Damage

Lichen planus is a relatively common mucocutaneous papulosquamous disorder of unknown etiology that is thought to be immunologically mediated. Ocular involvement of lichen planus (LP) is a rare event, which can lead to irreversible damage to the ocular surface and loss of vision from cicatrizing blepharoconjunctivitis and corneal scarring. Steroids are the first treatment choice. Treatment with topical ciclosporin A is also a possible treatment. We report a case of 79-year-old woman who was treated for long lasting severe inflammatory disease of a ocular surface. It led to blindness of one eye and low vision of the second eye. The diagnosis was made thanks to correlation of biopsy results from oral and ocular surface. The patient was also diagnosed with middle-stage dementia. Negative impact of steroid therapy on mental condition of this patient was considered. On the other hand, dementia could cause worse compliance with recommended treatment regime. Chronic inflammatory disease of ocular surface requires long lasting treatment very often and it is sometimes not as effective as expected. Discovering etiological causes of the disease is a priority for the right treatment. We emphasize also the key role of physical and mental condition in management of ocular surface disease.

scholarly journals A comparative study of apoptosis in reticular and erosive oral lichen planus

2012 ◽  
Vol 23 (5) ◽  
pp. 564-569 ◽  
Author(s):  
Juliana M. C. Brant ◽  
Maria Cássia F. Aguiar ◽  
Helenice A. M. Grandinetti ◽  
Luciana V. Rodrigues ◽  
Anilton C. Vasconcelos
Keyword(s):  
Lichen Planus ◽  
Inflammatory Disease ◽  
Oral Lichen Planus ◽  
Inflammatory Cell ◽  
Chronic Inflammatory Disease ◽  
Clinical Presentations ◽  
Tunel Reaction ◽  
Lymphocytic Infiltrates ◽  
Inflammatory Infiltrates ◽  
Oral Lichen

The oral lichen planus (OLP) is a chronic inflammatory disease, probably autoimmune, with different clinical forms. The most common types are the reticular and the erosive ones. Apoptosis participates in the destruction of basal keratinocytes, but its role in the perpetuation of the subepithelial lymphocytic infiltrates was not yet investigated. To evaluate the involvement of apoptosis in the epithelium and in subepithelial lymphocytic infiltrates, 15 samples of reticular and erosive OLP and 10 samples of healthy oral mucosa were collected and processed histologically. Apoptosis was quantified in the epithelium and in inflammatory cell infiltrates. TUNEL reaction was used to measure apoptosis in the infiltrates. Erosive OLP showed more intense epithelial apoptosis than reticular OLP and controls. In contrast, apoptosis in the inflammatory cell infiltrates was more frequent in reticular than in erosive OLP. Lymphocytes were the predominant cells within the inflammatory cell infiltrates and were more frequent in erosive OLP than in reticular type. These results suggest that different apoptotic levels are involved in the erosive/reticular switch in OLP, determining different clinical presentations. In conclusion, decreased apoptosis in inflammatory infiltrates may contribute to the persistence of T lymphocytes, worsening the attack to the epithelium in erosive OLP.

scholarly journals Management of Eumycetoma

2020 ◽  
Vol 32 (3) ◽  
pp. 232
Author(s):  
Tjokorde Istri Nyndia Vaniari ◽  
Sunarso Suyoso ◽  
Linda Astari ◽  
Yuri Widia ◽  
Sylvia Anggraeni ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Disease ◽  
Chronic Inflammatory Disease ◽  
Minor Trauma ◽  
Difficult Case ◽  
Infectious Agents ◽  
Granulomatous Lesions ◽  
Early Case ◽  
Localized Disease ◽  
A Minor

Background: Mycetoma is a chronic inflammatory disease of the skin that can extend to the fascia, tendons, muscles, and bones. Caused by a bacterium called actinomycetoma and a fungus called eumycetoma are responsible for mycetoma, both of which must be distinguished because they require different medical therapy. Eumycetoma is a localized disease, chronic, and growing slowly. Most of eumycetoma patients had delays in seeking medical care. Purpose: To provide an overview and discuss various aspects of eumycetoma, including its epidemiology, etiology, pathogenesis, classification, clinical picture, diagnosis, differential diagnosis, and therapy. Review: Eumycetoma infection begins as infectious agents enter through the skin with a minor trauma caused by objects contaminated with fungi, forming granular or granulomatous lesions with tract and sinus in there. The infection can spread from the site of inoculation into the muscles and bones. The diagnosis is based on anamnesis (chronic and painless), the triad of tumefaction, draining sinuses and grains, and laboratory investigation. It’s a difficult case, often recur and difficult to be surgical excisison, so that the best first option therapy is the combination of itraconazole and terbinafine itself as an alternative to surgical therapy at least 6 months. Conclusion: Eumycetoma is an infection caused by a fungus with granulomatous lesions with sinus formation and grains in it. The best first option therapy is the combination of itraconazole and terbinafine although it’s still an early case.

A Critical Review on Tamaka Shwasa (Bronchial Asthma) - An Ayurvedic View

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Sandip R. Baheti ◽  
Deepa Sharma ◽  
Saroj Devi ◽  
Amit Rai
Keyword(s):  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Critical Review ◽  
Modern Science ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
The Body ◽  
Natural Immunity ◽  
Shortness Of Breath ◽  
Asthma Symptoms

Difficulty in breathing or shortness of breath may be simply termed as Shwasa (Asthma), As per Ayurveda, Shwasa is mainly caused by the Vata and Kapha Doshas. Shwasa is broadly classified into five types in Maha Shwasa (Dyspnoea major), Urdhawa Shwasa (Expiratory Dyspnoea), Chinna Shwasa (Chyne-stroke respiration), Kshudra Shwasa (Dyspnoea minor), Tamaka Shwasa (Bronchial Asthma). In modern science Tamaka Shwasa can be correlated with Asthma, Asthma which is a chronic inflammatory disease of airway. In modern medicine there is no cure for Asthma, symptoms can typically be improved. In Ayurveda, Asthma can be effectively and safely manage the condition without inducing any drug dependency where Pachakarma procedures and use of internal medication detoxifies the body, provides nutrition and increases the elasticity of lung tissue it also develops natural immunity of the body thus decreasing episodic recurrence of the disease.

Intermammary Hidradenitis Suppurativa: Considerations on a Unique Presentation

2021 ◽  
pp. 1-4
Author(s):  
Ana Luísa João ◽  
Nélia Cunha ◽  
Joana Cabete
Keyword(s):  
Surgical Approach ◽  
Inflammatory Disease ◽  
Pilonidal Sinus ◽  
Hidradenitis Suppurativa ◽  
Chronic Inflammatory Disease ◽  
Pilonidal Sinus Disease ◽  
Sinus Disease ◽  
Case Presentation ◽  
Overweight Women

Introduction: Hidradenitis suppurativa (HS) is a potentially disabling chronic inflammatory disease. The intermammary location, not clearly specified in the usual phenotypic classifications, entails significant functional and cosmetic compromise. Case Presentation: Eleven cases of predominantly intermammary disease with multiple fistulization and disfiguring scarring were observed at our Department between January 2016 and March 2020. They were young (mean age = 22 years) obese or overweight women, in which the medical-surgical approach has led to variable results. Discussion/Conclusion: Intermammary HS possibly represents a unique phenotypic presentation, likely to be fistulizing and severe. We believe that anatomo-functional considerations, which can be paralleled to pilonidal sinus disease, contribute to its pathophysiology and striking appearance, and further emphasize the importance of multidisciplinary endeavor to reduce the morbidity associated with this seemingly overlooked location.

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