scholarly journals VITILIGO AND COMORBID PSYCHOSOMATIC DISORDERS

2019 ◽  
Vol 22 (1-2) ◽  
pp. 33-38
Author(s):  
Asmik A. Varzhapetyan ◽  
I. Yu Dorozhenok ◽  
K. M Lomonosov
Keyword(s):  
Clinical Picture ◽  
Skin Diseases ◽  
The Body ◽  
Stress Effect ◽  
Psychosomatic Disorders ◽  
Psychological Study ◽  
Psychosomatic Aspects ◽  
Subjective Reaction ◽  
Idiopathic Disease ◽  
Significant Factors

Vitiligo is a chronic idiopathic disease characterized by appearance of depigmented spots and discolored hairs in various parts of the body due to the destruction and reducing the number of melanocytes. Despite the absence of somatogenic appearance psychosomatic aspects of vitiligo are extremely relevant to study in view of high psychosocial significance associated with the pronounced stigmatizing effects. 62 vitiligo patients were examined. Among comorbid psychosomatic disorders there were found out psychogenic manifestations - 25 (40.3%) and nosogenic reactions due to stress effect of the dermatosis - 37 (50.7%): sociophobic - 17, masked hypochondria - 13, overvalued hypochondria of beauty - 7 patients. Psychogenic manifestations with the participation of objectively severe and subjectively significant factors can attribute vitiligo to psychosomatic skin diseases. In the clinical picture of nosogenic disorders, various forms of dissociation between the prevalence of dermatosis and subjective reaction to the cosmetic defect were revealed, which is due to the structure of the personality and somatoperceptive accentuation of the patient. The results can be implemented in dermatological practice, which will significantly optimize the treatment and compliance of patients with vitiligo. Objective: a complex clinical (dermatological, psychopathological) and psychological study of psychosomatic disorders in vitiligo.

Inspector Quadro - the complex of preparation for the treatment of ectoand endoparasitoses in cats and dogs

2018 ◽  
Vol 12 (2) ◽  
pp. 75-84
Author(s):  
M.V. Arisov ◽  
I.P. Belykh ◽  
V.V. Artemov
Keyword(s):  
Body Weight ◽  
Clinical Picture ◽  
High Efficiency ◽  
The Body ◽  
Negative Effects ◽  
Laboratory Methods ◽  
Diagnosis Of Infection

The purpose of the research: the study of the efficacy of the preparations for veterinary use "Inspector Quadro C" and "Inspector Quadro K" against ecto- and endoparasitoses of dogs and cats. Materials and methods. Studies were conducted on spontaneously infected dogs and cats of different sexes, age, weight and breed. The diagnosis of infection with ectoparasites was made based on the clinical picture and laboratory methods of investigation (microscopy of scrapings taken from ectoparasitized skin areas, examination of the coat for fleas, lice, worms, ixodids). Infection with helminths was established by detecting eggs of helminths in faeces of animals by the method of Füleleborn and mature segments of cestodes. Preparations were applied to the animals by drip application on dry undamaged skin in places inaccessible to licking in a dose of 0.1-0.4 ml per 1 kg of body weight. The results were statistically processed. Results and discussion. "Inspector Quadro S" and "Inspector Quadro K" showed 100% efficacy at sarcoptosis in dogs, notoedrosis in cats, otodectosis in dogs and cats, ixodidoses and entomoses. "Inspector Quadro C" showed a high efficiency (92.3%) at demodecosis in dogs. However, single mites were found in one dog. 100% efficacy of "Inspector Quadro C" and "Inspector Quadro K" has been established against intestinal nematodes and cestodes in dogs and cats. Negative effects of drugs on the body of animals have not been revealed.

DIAGNOSTICS AND TREATMENT OF POISONING WITH THALLIUM

2018 ◽  
pp. 9-15 ◽  
Author(s):  
L. B. Zavaliy ◽  
A. Yu. Simonova ◽  
M. M. Potskhveriya ◽  
Yu. N. Ostapenko ◽  
M. G. Gadzhieva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Picture ◽  
Clinical Guidelines ◽  
The Body ◽  
Biological Media ◽  
Pathophysiological Mechanisms ◽  
Thallium Poisoning ◽  
The World

Cases of thallium poisonings are regularly reported in media. In the present work, the world experience in diagnostics and treatment of victims with thallium poisoning has been compiled and summarized, search for clinical guidelines for the diagnostics, treatment and rehabilitation of patients has been carried out. The toxicokinetics and toxicodynamics, as well as pathophysiological mechanisms of thallium influence on the body are described in detail. Toxic and lethal concentrations of poison in biological media, as well as its tropicity to various tissues and body systems were determined. The clinical picture depending on the timing of poisoning and the dose of poison is described in detail. Difficulties of the differential diagnosis are defined. The most interesting cases of criminal and household poisonings with various terms of establishment of the diagnosis, doses of poisoning and outcomes are presented.

Molecular Targets of Phytochemicals for Skin Inflammation

2018 ◽  
Vol 24 (14) ◽  
pp. 1533-1550 ◽  
Author(s):  
Jong-Eun Kim ◽  
Ki Won Lee
Keyword(s):  
Skin Diseases ◽  
Molecular Targets ◽  
Skin Inflammation ◽  
Mechanisms Of Action ◽  
The Body ◽  
Cellular Damage ◽  
Aesthetic Appearance ◽  
Immune Mediated ◽  
Skin Conditions ◽  
Effects Of Aging

Skin is a protective organ and the largest of the human body. Due to its pivotal role in aesthetic appearance, skin health has a significant impact on quality of life. Chronic inflammation of the skin often marks the beginning of various skin diseases. Immune-mediated responses serve to protect the body from external insults and require succinct control, and can lead to ongoing cellular damage and various skin conditions if left unchecked. Studies have shown that phytochemicals can alter processes involved in skin inflammation and alleviate the effects of aging, cancer, atopic dermatitis, psoriasis, and vitiligo. Direct molecular targets of some phytochemicals have been identified and their precise mechanisms of action investigated. In this review, we summarize recent findings on the effects of phytochemicals on skin inflammation and the mechanisms of action involved.

STUDIES OF STABLE IODINE METABOLISM AS A GUIDE TO THE INTERPRETATION OF RADIOIODINE TESTS

1961 ◽  
Vol 37 (4) ◽  
pp. 597-606 ◽  
Author(s):  
D. A. Koutras ◽  
W. D. Alexander ◽  
W. W. Buchanan ◽  
J. Crooks ◽  
E. J. Wayne
Keyword(s):  
Clinical Features ◽  
Thyroid Function ◽  
Clinical Picture ◽  
Diagnostic Errors ◽  
Previous Treatment ◽  
The Body ◽  
High Uptake ◽  
Iodine Metabolism ◽  
Inorganic Iodine ◽  
Stable Iodine

ABSTRACT The results of radioiodine tests are dependent not only on thyroid function but also on the size of the iodine pools in which the radioiodine is diluted. The significance of the second factor is analysed in this paper and it is shown that there is a danger in interpreting radioiodine tests in isolation. The uptake of 131I is inversely related to the extrathyroidal inorganic iodine pool and the PB131I is inversely related to the intrathyroidal iodine pool. Both these pools may be diminished in euthyroid persons and thus a high uptake of 131I may be associated with a high PB131I and so lead to false diagnostic conclusions. In order to avoid diagnostic errors standard 131I tests should never be reported without some knowledge of relevant clinical features, for example, whether there is the possibility of prolonged iodine deficiency, of previous treatment, of Hashimoto's disease, or of dyshormonogenesis. In this way due weight can be given to factors which increase or decrease the iodine pools of the body and discrepancies between the clinical picture and radioiodine tests become obvious. More specific investigations can then be undertaken in appropriate cases.

Medyczne i humanistyczne zagadnienia związane z psychodermatologią w praktyce lekarza rodzinnego, ginekologa i seksuologa

2020 ◽  
Vol 23 (3) ◽  
Author(s):  
Grażyna Jarząbek-Bielecka ◽  
Katarzyna Plagens-Rotman ◽  
Małgorzata Mizgier ◽  
Piotr Merks ◽  
Magdalena Czarnecka-Operacz ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Family Doctor ◽  
Holistic Approach ◽  
Self Esteem ◽  
Skin Lesions ◽  
The Body ◽  
Skin Changes ◽  
Developmental Age ◽  
Pain And Suffering ◽  
Similar Search

A family doctor, as well as a sexologist, gynecologist, in his medical practice encounters problems related to skin diseases significantly affecting the sense of femininity or masculinity. An example of such an issue, especially in gynecology of developmental age, is the problem of skin changes associated with androgenization syndromes. Typical dermatological diseases are sometimes associated with enormous pain, not only physical, but also mental, resulting from the fact that skin disease processes significantly disfigure the body, lower self-esteem and significantly affect the sexual sphere. Selected aspects related to the holistic approach to the issue of pain and suffering, also related to skin lesions, are presented. This issue, like all medical fields, is a source of philosophical reflection. It is inseparable from psychodermatology. The experience of the SARS-CoV-2 coronavirus pandemic, taking into account skin lesions, also prompts a similar search.

SCREENING CYTOCHEMICAL METHODS IN THE DIAGNOSIS OF PROFESSIONAL AND PROFESSIONALLY CAUSED SKIN PATHOLOGY

2021 ◽  
Author(s):  
E.K. Krasavina ◽  
◽  
I.V. Yatsyna ◽  
I.Y. Zhadan
Keyword(s):  
Early Diagnosis ◽  
Working Conditions ◽  
Skin Diseases ◽  
Hydrolytic Enzymes ◽  
The Body ◽  
Social Adaptation ◽  
Social Significance ◽  
Low Levels ◽  
Degree Of Severity ◽  
Cytochemical Parameters

Abstract: Introduction: Skin diseases of professional etiology remain to this day an urgent problem, despite the low levels of morbidity according to official statistics, due to the high medical and social significance of this pathology. For early diagnosis of occupational and occupational-related skin pathology, it is necessary to investigate laboratory markers that correlate with this pathology. In this regard, a promising direction is to study the activity indicators of hydrolytic enzymes of neutrophils: alkaline and acid phosphatases, the level of myeloperoxidase. Objective: to study and evaluate the effectiveness of cytochemical methods for diagnosing the reactivity of the body in workers exposed to a chemical factor in the workplace. Research methods: hygienic assessment of working conditions of woodworking workers, assessment of the health status and cytochemical parameters of workers. Analysis of the obtained data by methods of mathematical statistics. Results: A hygienic assessment of working conditions and an inspection, with a complex of cytochemical studies, of 148 employees of the chipboard manufacturing enterprise were carried out. The leading factor affecting the body of workers is chemical. A direct strong correlation (r=0.7) was established between the level of dermatological morbidity and the indicators of air pollution of the working area with formaldehyde. Skin pathology was detected in 32.4% of the examined workers. At the same time, the indicators of cytochemical activity in the examined group correlated with the degree of severity of the skin process. Conclusions: Cytochemical indicators in combination with other clinical and diagnostic studies allow us to assess the risk of developing professional and professionally caused skin pathology, which allows us to use them for early diagnosis, and thus contribute to the preservation of labor potential and social adaptation of workers exposed to occupational hazards.

scholarly journals Developing a Multi-variate Logistic Regression Model to Analyze Accident Scenarios: Case of Electrical Contractors

2020 ◽  
Vol 17 (13) ◽  
pp. 4852
Author(s):  
Pouya Gholizadeh ◽  
Behzad Esmaeili
Keyword(s):  
Logistic Regression ◽  
Regression Model ◽  
Odds Ratio ◽  
Logistic Regression Model ◽  
The Body ◽  
Occupational Accidents ◽  
Multivariate Logistic Regression Model ◽  
Ratio Analysis ◽  
Accident Scenarios ◽  
Significant Factors

The ability to identify factors that influence serious injuries and fatalities would help construction firms triage hazardous situations and direct their resources towards more effective interventions. Therefore, this study used odds ratio analysis and logistic regression modeling on historical accident data to investigate the contributing factors impacting occupational accidents among small electrical contracting enterprises. After conducting a thorough content analysis to ensure the reliability of reports, the authors adopted a purposeful variable selection approach to determine the most significant factors that can explain the fatality rates in different scenarios. Thereafter, this study performed an odds ratio analysis among significant factors to determine which factors increase the likelihood of fatality. For example, it was found that having a fatal accident is 4.4 times more likely when the source is a “vehicle” than when it is a “tool, instrument, or equipment”. After validating the consistency of the model, 105 accident scenarios were developed and assessed using the model. The findings revealed which severe accident scenarios happen commonly to people in this trade, with nine scenarios having fatality rates of 50% or more. The highest fatality rates occurred in “fencing, installing lights, signs, etc.” tasks in “alteration and rehabilitation” projects where the source of injury was “parts and materials”. The proposed analysis/modeling approach can be applied among all specialty contracting companies to identify and prioritize more hazardous situations within specific trades. The proposed model-development process also contributes to the body of knowledge around accident analysis by providing a framework for analyzing accident reports through a multivariate logistic regression model.

Effect of factors of organizational structure influencing nonphysical waste in road projects of developing countries

2020 ◽  
Vol 27 (10) ◽  
pp. 3135-3153
Author(s):  
Muhammad Irfan ◽  
Muhammad Sohail Anwar Malik ◽  
Syyed Sami Ul Haq Kaka Khel
Keyword(s):  
Developing Countries ◽  
Organizational Structure ◽  
The Body ◽  
Management Support ◽  
Cost Overrun ◽  
Cost Overruns ◽  
Content Type ◽  
Factors Influencing ◽  
Road Projects ◽  
Significant Factors

PurposeThe purpose of this research is to rank the most significant factors of organizational structure that can reduce time and cost overruns (nonphysical waste) in road projects of the developing countries. Additionally, the effect of factors of organizational structure on nonphysical waste in road projects is also measured.Design/methodology/approachFactors of organizational structure causing time and cost overrun are extracted through a content analysis of the published literature. Moreover, a questionnaire survey is carried out involving 128 professionals to assess the effect of organizational structure factors on time and cost overrun. Finally, to obtain a more objective evaluation, relative importance index and regression analysis techniques are utilized, and the most severe factors influencing time and cost overrun are indicated.FindingsThis study found out that top management support and procurement procedures are the most significant factors influencing time and cost overruns in road projects of the developing countries.Originality/valueA small number of studies have been conducted to investigate the effect of factors of organizational structure on time and cost overrun in the construction industry. And even more, its relation with respect to road projects of the developing countries is limited. This research highlights the effect of most significant factors of organizational structure that influence the nonphysical waste in road projects of the developing countries. Therefore, this study adds to the body of knowledge by recommending that all the stakeholders of construction project should pay close attention toward these factors to control the enigma of time and cost overrun. It might also prove helpful, if implemented to its full extent, in all the road construction activities undertaken.

Significant factors influencing outsourcing decision for facilities management (FM) services

2015 ◽  
Vol 33 (1) ◽  
pp. 59-82 ◽  
Author(s):  
Dubem Ikediashi ◽  
Onuwa Okwuashi
Keyword(s):  
Point Of View ◽  
The Body ◽  
Public Hospitals ◽  
Facilities Management ◽  
Content Type ◽  
Body Of Knowledge ◽  
Outsourcing Decision ◽  
Practical Implications ◽  
Insight Into ◽  
Significant Factors

Purpose – The purpose of this paper is to investigate and conceptualise significant factors influencing decision to outsource facilities management (FM) services in Nigeria’s public hospitals. Design/methodology/approach – Data for this study were collected using a cross-sectional questionnaire survey. A total of 85 responses were received from the six states comprising the study area while 11 of them were discarded due to missing data resulting in 74 usable responses. This gave an overall response rate of 61 per cent. Data collected were analysed using descriptive and inferential statistics as well as principal component analysis. Findings – Findings revealed that 25 of the 31 factors were significant in explaining the decision to outsource FM service in Nigeria’s public hospitals; while 15 of them grouped into six broad categories were selected based on their factor loadings during further analysis. Besides, it was also established from the study that “to improve performance standard”, “to improve quality of services” and “to improve timely delivery of services” are the top three rated factors. Research limitations/implications – The study complements the body of knowledge on “make or buy” decision theory by provided empirical insight into key attributes of outsourcing decision motives for FM services from the point of view of Nigeria’s public sector spectrum that can serve as benchmark for deciding on whether to outsource or not. Practical implications – The study also has practical implications. More is now known as a result of this research about what factors constitute drivers for outsourcing FM services within the context of Nigeria’s public hospitals. With an aggregate opinion from 74 public hospitals, the study provides hospital administrators and public managers with a list of prioritised factors for making rational informed decision about outsourcing of services in the hospitals. Originality/value – The study complements the body of knowledge on “make or buy” decision theory by providing empirical insight into key attributes of outsourcing decision motives for FM services from the point of view of Nigeria’s public healthcare.

scholarly journals Canine sporotrichosis: report of 15 advanced cases

2018 ◽  
Vol 38 (3) ◽  
pp. 477-481 ◽  
Author(s):  
Mariana B. Mascarenhas ◽  
Natália L. Lopes ◽  
Thiago G. Pinto ◽  
Thiago S. Costa ◽  
André P. Peixoto ◽  
...  
Keyword(s):  
Rio De Janeiro ◽  
Skin Diseases ◽  
Sporothrix Schenckii ◽  
The Body ◽  
Nasal Discharge ◽  
Fungal Culture ◽  
Dimorphic Fungus ◽  
Cutaneous Lesions ◽  
Distal Aspect ◽  
Disseminated Disease

ABSTRACT: Sporotrichosis is a chronic, granulomatous and usually lymphocutaneous infection of animals and humans, caused by a dimorphic fungus, Sporothrix schenckii complex. The disease in dogs is considered rare, however, in the last years a crescent registration of cases was observed in Brazil, especially in the city of Rio de Janeiro. Fifteen dogs with ulcerated cutaneous lesions were seen at the Dermatology Service in the Small Animal’s Hospital at Universidade Federal Rural do Rio de Janeiro, between January 2014 and October 2015. Most lesions were located on the head, mainly the nose. Lesions were even seen on the chest, disseminated on the body and on the limbs. Three dogs (20%) exhibited the cutaneous-lymphatic form, with lesions initially on the distal aspect of one leg and ascending via lymphatics up the leg to the trunk and head. It was not ruled out the disseminated form in at least 3 dogs (20%). They had consistent signs of generalized or disseminated disease exhibiting respiratory symptoms (nasal discharge, sneezing, stertorous breathing), anorexia and weight loss. Draining tracts and cellulitis were very common. Some had large areas of skin necrosis with exposure of muscle and bone. Definitive diagnosis was obtained by cytological examination of exudates, histological examination, and/or isolation of S. schenckii complex by fungal culture. Because of the severity of the lesions that mimic other disorders like neoplasms or autoimmune skin diseases, and due to the difficulties of getting an accurate diagnosis, this study describes 15 advanced cases of canine sporotrichosis.

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