scholarly journals Clinical course, diagnosis and treatment of gastrointestinal stromal tumors

2011 ◽  
Vol 3 (1) ◽  
pp. 59-64
Author(s):  
Yulyi V. Ivanov
Keyword(s):  
Prognostic Factors ◽  
Gastrointestinal Tract ◽  
Case History ◽  
Gastrointestinal Stromal Tumors ◽  
Clinical Course ◽  
Target Therapy ◽  
Diagnosis And Treatment ◽  
Successful Operation ◽  
Stromal Tumors ◽  
History Of

The article summarizes up-to-date data of the pathogenesis, diagnosis, and treatment conceptions of the stromal tumors of gastrointestinal tract (GIST). Prognostic factors for progression (recurrence or metastasis) for GIST are reported. Special attention is given to immuno-histochemical method of diagnostics and target therapy for these kinds of tumors. We present the case history of successful operation in a patient with giant intestinal stromal tumor of the stomach, sprouting into neighbouring organs and tissues.

Clinicopathological Features and Prognostic Factors of Rectal Gastrointestinal Stromal Tumors

2013 ◽  
Vol 17 (4) ◽  
pp. 793-798 ◽  
Author(s):  
C. C. Xiao ◽  
S. Zhang ◽  
M. H. Wang ◽  
L. Y. Huang ◽  
P. Wu ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Gastrointestinal Stromal Tumors ◽  
Clinicopathological Features ◽  
Stromal Tumors

Psoas Abscess: Diagnosis and Treatment

2006 ◽  
Vol 5 (1) ◽  
pp. 13-16
Author(s):  
Raj Kandasamy ◽  
◽  
Asha Srikanth ◽  
SM Rutter ◽  
CJ Butcher ◽  
...  
Keyword(s):  
Clinical Features ◽  
Case History ◽  
Diagnostic Tests ◽  
Psoas Abscess ◽  
Diagnosis And Treatment ◽  
Uncommon Presentation ◽  
Appropriate Treatment ◽  
History Of

Psoas abscess is an uncommon presentation on the acute medical take. However recognition and appropriate treatment is essential. This review is designed to highlight the clinical features, microbiology, diagnostic tests and treatment for this condition. In order to illustrate some of the pitfalls and complexities in the management of psoas abscess we have included a case history of a patient who was recently treated in our department.

Evaluation of Prognostic Factors and Their Capacity to Predict Biological Behavior in Gastrointestinal Stromal Tumors

2011 ◽  
Vol 19 (4) ◽  
pp. 448-461 ◽  
Author(s):  
Silvia Calabuig-Fariñas ◽  
José Antonio López-Guerrero ◽  
Samuel Navarro ◽  
Isidro Machado ◽  
Andrés Poveda ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Gastrointestinal Stromal Tumors ◽  
Biological Behavior ◽  
Stromal Tumors

scholarly journals Primary Extra-gastrointestinal Stromal Tumor of Retroperitoneum

2012 ◽  
Vol 6 ◽  
pp. CMO.S9180 ◽  
Author(s):  
Claudio Casella ◽  
Vincenzo Villanacci ◽  
Filippo D'adda ◽  
Manuela Codazzi ◽  
Bruno Salerni
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumor ◽  
Radiological Evaluation ◽  
Retroperitoneal Mass ◽  
Stromal Tumors ◽  
Mesenchymal Neoplasms ◽  
Paravertebral Region ◽  
Histology And Immunohistochemistry

Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. More rarely neoplasms with histology and immunohistochemistry similar to GISTs may occur outside the gastrointestinal tract (omentum, mesentery and retroperitoneum) and are so-called Extra-gastrointestinal Stromal Tumors (EGISTs). EGISTs arising in the retroperitoneum are extremely rare: to date, only 58 cases have been reported in the literature. Case Report We herein report a case of a primary EGIST of the retroperitoneum surgically treated. The pre-operative radiological evaluation showed a retroperitoneal mass, placed in left paravertebral region. Results Morphological and immunohistochemical features led to a diagnosis of extra-gastrointestinal stromal tumor (intermediate-low risk form). Conclusions As a result of the rarity of reports of primary EGISTs of retroperitoneum we need to analyze the data of reported cases in order to gain a better understanding about the pathogenesis, prognosis and optimal treatment of this disease.

Large Omental Metastases of a Gastrointestinal Stromal Tumor

Medicina ◽  
2011 ◽  
Vol 47 (11) ◽  
pp. 86
Author(s):  
Povilas Ignatavičius ◽  
Tomas Petraitis ◽  
Žilvinas Saladžinskas ◽  
Lilija Butkevičienė ◽  
Kristina Žvinienė
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Interstitial Cells Of Cajal ◽  
Metastatic Tumor ◽  
Stromal Tumor ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Cells Of Cajal

Gastrointestinal stromal tumors are rare tumors, originating from the interstitial cells of Cajal. They are the most common mesenchymal tumors of the gastrointestinal tract. Metastatic tumor is treated with imatinib mesylate. A case of large metastases of a gastrointestinal stromal tumor to the omentum, diagnosis and treatment principles are presented in this case report.

scholarly journals Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors

2013 ◽  
Vol 73 (12) ◽  
pp. 3499-3510 ◽  
Author(s):  
Sylvie Rusakiewicz ◽  
Michaela Semeraro ◽  
Matthieu Sarabi ◽  
Mélanie Desbois ◽  
Clara Locher ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors

scholarly journals Multiple Gastric Gastrointestinal Stromal Tumors in a Patient with Neurofibromatosis Type 1

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Makoto Tomatsu ◽  
Jun Isogaki ◽  
Takahiro Watanabe ◽  
Kiyoshige Yajima ◽  
Takuya Okumura ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Gastrointestinal Stromal Tumors ◽  
Kinase Inhibitor ◽  
Submucosal Tumor ◽  
Neurofibromatosis Type ◽  
Stromal Tumors ◽  
Serosal Surface ◽  
History Of ◽  
Small Intestinal

Gastrointestinal stromal tumors (GISTs) are relatively common in neurofibromatosis type 1 (NF 1) patients. Approximately 90% of GISTs associated with NF 1 are located in the small intestine, while sporadic GISTs are most commonly located in the stomach. Here we report an extremely rare case of an NF 1 patient with multiple gastric GITs (90 or more) but without multiple small intestinal tumors. A 63-year-old female patient who had a history of NF 1 underwent surgery for a gastric neuroendocrine tumor and gastric submucosal tumor (SMT). During the operation, multiple small nodules were identified on the serosal surface of the upper stomach. SMT and multiple nodules on the serosal surface were diagnosed as GISTs consisting of spindle cells positive for KIT, CD34, and DOG-1. Both GIST and the normal gastric mucosa showed no mutations not only in the c-kitgene (exons 8, 9, 11, 13, and 17) but also in thePDGFRAgene (exons 12, 14, and 18). This patient is being followed up without the administration of a tyrosine kinase inhibitor.

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