scholarly journals Practical aspects of cardiovascular risk factors identify in patients with diabetes type 1 and 2

2011 ◽  
Vol 3 (1) ◽  
pp. 4-9
Author(s):  
Mehman N. Mamedov ◽  
Marina N. Kovrigina ◽  
Marina B. Buzurtanov

The aim of this study was to investigate the characteristics of the risk factors and comparative analysis of different methods of identify of cardiovascular risk factors in outpatient with diabetes mellitus (DM) type 1 and 2. Methods. In cross-sectional clinical study included 244 persons with type 1 and type 2 mean age 46,4 yrs. All patients were interviewed using a questionnaire of WHO, they were measured blood pressure, heart rate, anthropometric data, including total fat mass with fat analyzer OMRON BF508. All patients were also measured venous and capillary blood glucose level, glycated hemoglobin (%), total cholesterol and triglycerides. Results. The difference between the two measurement glucose methods (in venous and capillary blood) was 6,7 0,6%. In patients with type 1 diabetes hypertension occurs 2.5 times in less compared with patients with type 2 diabetes. The difference between blood pressure measured by mechanical and automatic devices was less than 1%. The percentage of body fat, including visceral fat, both women and men with type 2 diabetes by age corresponds to the high deviation from the norm. Most men and women with type 1 and type 2 had hypercholesterolemia. Conclusion. Traditional cardiovascular risk factors are identified, not only among individuals with type 2 diabetes, but among patients with type 1 diabetes.

2016 ◽  
Vol 34 (3) ◽  
pp. 421-428 ◽  
Author(s):  
Trevor A. Mori ◽  
Valerie Burke ◽  
Renate R. Zilkens ◽  
Jonathan M. Hodgson ◽  
Lawrence J. Beilin ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1476-P
Author(s):  
MITRA MOSSLEMI ◽  
HANNAH L. PARK ◽  
CHRISTINE E. MCLAREN ◽  
NATHAN D. WONG

2017 ◽  
Vol 25 (2) ◽  
pp. 93-105 ◽  
Author(s):  
Junping Wei ◽  
Huijuan Zheng ◽  
Liansheng Wang ◽  
Qiuhong Wang ◽  
Fan Wei ◽  
...  

Background Mobile health interventions utilising telephone calls are promising tools for diabetes management. However, there is still a lack of convincing evidence demonstrating their beneficial effects on cardiovascular risk factors. The aim of this meta-analysis of randomised controlled trials was to assess the effect of telephone calls on glycaemic control and other cardiovascular risk factors in type 2 diabetes mellitus patients. Methods Two independent reviewers searched three online databases (PubMed, the Cochrane Library and EMBASE) to identify relevant English-language randomised controlled trials up to September 2017. Randomised controlled trials that assessed the effects of telephone calls on glycaemic control and other cardiovascular risk factors in type 2 diabetes mellitus patients were included. Effect size was calculated for changes in glycosylated haemoglobin A1c, weight, blood pressure and lipid levels using fixed- or random-effects models. Results Eighteen studies involving 3954 patients were included in the meta-analysis. Compared with usual care, telephone calls significantly decreased glycosylated haemoglobin A1c, by 0.12% (95% confidence interval: −0.22% to −0.02%). Univariate regression analysis showed that none of the covariates (number of participants, baseline age, baseline glycosylated haemoglobin A1c, duration of diabetes, call maker, number of calls and duration of study) had an impact on glycosylated haemoglobin A1c. For other cardiovascular risk factors, telephone calls significantly reduced systolic blood pressure by 0.19 mm Hg (95% confidence interval: −0.34% to −0.03%) but non-significantly changed diastolic blood pressure, body mass index, low-density lipoprotein cholesterol, total cholesterol, triglyceride or high-density cholesterol levels. Conclusions This meta-analysis supports the hypothesis that telephone calls offer moderate benefits for glycosylated haemoglobin A1c and systolic blood pressure reduction among type 2 diabetes mellitus patients. However, the data remain insufficient regarding the association of telephone calls with lowered diastolic blood pressure, body mass index or improved lipoprotein profiles.


2012 ◽  
Vol 33 (6) ◽  
pp. 313-320 ◽  
Author(s):  
Salvador Muñoz-Barrios ◽  
Iris Paola Guzmán-Guzmán ◽  
José Francisco Muñoz-Valle ◽  
Aralia Berenice Salgado-Bernabé ◽  
Lorenzo Salgado-Goytia ◽  
...  

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolismand is associatedwith obesity, dyslipidemias, hypertension (HTN) and type 2 diabetes mellitus (T2DM).LPLgene polymorphisms can be related with the development of cardiovascular risk factors. The present study was conducted to analyze the relationship of theHindIIIand S447X polymorphisms inLPLgene with cardiovascular risk factors in Mexican families. The study population comprised ninety members of 30 Mexican families, in which an index case had obesity, were included in the study. We evaluated the body composition by bioelectrical impedance. Peripheral blood samples were collected to determine biochemical parameters. Screening for both polymorphisms was made by PCR-RFLPs. In the parents, both polymorphisms were in Hardy-Weinberg’s equilibrium. We found that the genotype T/T ofHindIIIwas associated with diastolic blood pressure ≧ 85 mmHg (OR = 1.1;p= 0.011), whereas the genotype C/C of S447X was associated with systolic blood pressure ≧ 130 mmHg (OR = 1.2;p< 0.001), diastolic blood pressure ≧ 85 mmHg (OR = 1.3;p< 0.001), T2DM (OR = 1.3;p< 0.001) and with increase of total cholesterol (β = 23.6 mg/mL;p= 0.03). These data suggest that theHindIIIand S447XLPLgene polymorphisms can confer susceptibility for the development of hypertension and T2DM in Mexican families.


Author(s):  
Milena M. Cojić ◽  
Ljiljana Cvejanov-Kezunović ◽  
Jelena Stanković ◽  
Nebojša Kavarić ◽  
Maja Koraćević ◽  
...  

Some observational studies have shown that only a small number of diabetic patients achieve optimum control of glycaemia and cardiovascular risk factors. The aim of this study was to analyze whether patients with type 2 diabetes mellitus treated in primary care achieve adequate control of glycemic levels and cardiovascular risk factors. This was a retrospective, record-based, cross-sectional study that included eligible patients from 35 to 90 years old with type 2 diabetes mellitus treated in Primary Health Care Center in Podgorica. We investigated electronic records of 531 diabetic patients. The observed prevalence of type 2 diabetes mellitus among individuals between ages 35 and 90 years, was 11,84 %. Half of the patients were female. The mean age was 65,88±9,86 years. The mean value of HbA1c was 7,56±1,71. Fifty-nine percents of patients achieved optimal levels of HbA1c ≤ 7 %. Also, more than half of patients achieved target levels of blood pressure while 27.9% achieved LDL ≤ 2.6 mmol/L. Fifty percent of patients were non-smokers and 45.1 % were obese. Among patients on primary prevention only 5.7 % had met all target levels while on secondary prevention that number was even smaller 3.7 %. Our study showed that control of HbA1c and blood pressure was similar to other studies but reaching target levels of LDL was challenging for our patients. Further analysis are needed in order to discover the reasons for poor control of certain CVRF and to develop strategies for its optimal management.


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