scholarly journals Ursodeoxycholic acid for the prevention of gallstone disease after bariatric surgery

2021 ◽  
Vol 12 (2) ◽  
pp. 54-59
Author(s):  
Alexander V. Smirnov ◽  
Yuri V. Ivanov ◽  
Vladimir R. Stankevich ◽  
Valentin I. Sharobaro ◽  
Eugen A. Velichko
Keyword(s):  
Bariatric Surgery ◽  
Ursodeoxycholic Acid ◽  
De Novo ◽  
Gallstone Disease ◽  
First Year ◽  
Disease Development ◽  
Prophylactic Effect ◽  
Bariatric Patients ◽  
Longitudinal Gastrectomy

Background: The development of gallstone disease (GSD) after bariatric surgery is a significant problem. The prophylactic effect of ursodeoxycholic acid (UDCA) preparations on the occurrence of cholelithiasis after gastric bypass and longitudinal gastrectomy has been studied. Aims: The aim of the study was to evaluate the effectiveness of ursodeoxycholic acid preparations in the prevention of cholelithiasis in patients after bariatric surgery. Methods: The results of a year-long follow-up for 128 patients after bariatric surgery were analyzed. In 68 patients, the prophylaxis of the gallstone disease development was not performed. 60 patients took a daily 500 mg dose of UDCA orally. Results: Cholelithiasis had developed in 17 (25%) patients who did not undergo the prophylaxis of cholelithiasis. Of these, 10 (14.7%) underwent cholecystectomy. Among those patients who took UDCA drugs, stones in the gallbladder were found in 7 (11.6%), and only one patient (1.7%) required a surgical treatment. Conclusion: UDCA administration during the first year after bariatric surgery in the amount of 500 mg per day significantly reduces the likelihood of the de novo cholelithiasis development. The medical prophylaxis of gallstone disease should be included in the standards of bariatric patients' management.

scholarly journals Prevalence of All-Cause Mortality and Suicide among Bariatric Surgery Cohorts: A Meta-Analysis

2018 ◽  
Vol 15 (7) ◽  
pp. 1519 ◽  
Author(s):  
Russell Lim ◽  
Melvyn Zhang ◽  
Roger Ho
Keyword(s):  
Bariatric Surgery ◽  
Analytical Study ◽  
Meta Analysis ◽  
Well Being ◽  
Mortality Rates ◽  
Pooled Prevalence ◽  
All Cause Mortality ◽  
Bariatric Patients ◽  
Post Bariatric Surgery

Introduction: Prior meta-analysis has reported mortality rates among post-operative bariatric patients, but they have not considered psychiatric factors like suicide contributing to mortality. Objectives: The current meta-analysis aims to determine the pooled prevalence for mortality and suicide amongst cohorts using reported suicides post bariatric surgery. It is also the aim of the current meta-analytical study to determine moderators that could account for the heterogeneity found. Results: In our study, the pooled prevalence of mortality in the studies which reported suicidal mortality was 1.8% and the prevalence of suicide was 0.3%. Mean body mass index (BMI) and the duration of follow-up appear to be significant moderators. Conclusions: Given the prevalence of suicide post bariatric surgery, it is highly important for bariatric teams to consider both the medical and psychiatric well-being of individuals pre- and post-operatively.

scholarly journals Factors associated with different patterns of weight change after bariatric surgery: A longitudinal study

2021 ◽  
Author(s):  
Diana Cristina Henao Carrillo ◽  
Ana María Gómez ◽  
Oscar Muñoz ◽  
Claudia Rubio ◽  
Natalia Rodríguez ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bariatric Surgery ◽  
Weight Loss ◽  
Longitudinal Study ◽  
Estimating Equation ◽  
First Year ◽  
Factors Associated ◽  
Modifiable Factors ◽  
Over Time

Abstract Background Bariatric surgery is the most effective treatment for obesity. During long-term follow-up, weight loss (WL) is variable between subjects. The aim of this study is to assess the change in percentage of total weight loss (%TWL) and excess weight loss (%EWL) and to describe the factors associated with greater or lesser WL over time. Methods Longitudinal study including patients treated with laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (LSG) and followed at Hospital Universitario San Ignacio, Bogotá (Colombia). Baseline data was recorded before surgery. Follow-up was performed at 3 (n=192), 6 (n=190), 9 (n=188), 12 (n=186), 24 (n=99) and 36 (n=30) months. Generalized Estimating Equation (GEE) analysis was used to assess the change in %TWL and %EWL over time. Results 196 patients were included (82.4% female, BMI 41.3±5.2 kg/m2). The tendency to increase on %TWL (31.6±6.6) and %EWL (80.2 RIQ 70.7-97.3) was evident in the first year, stabilizing after that. Nutritionist follow-up, baseline BMI>40 kg/m2 and WL≥10kg before surgery were associated with an average higher increase of %TWL (2.39% p=0.014, 0.41% p<0.001 and 0.37% p=0.003, respectively). Subjects who performed physical activity >30 minutes/day after surgery reduced %TWL in 0.74% (p=0.009). Similar findings were described on %EWL. Conclusion Follow-up during the first year after bariatric surgery is critical to achieving %TWL and %EWL goals. This study suggests that modifiable factors such as nutritional follow-up, WL before surgery and time of physical activity are associated with a significant change in %TWL and %EWL during follow-up by a multidisciplinary team.

Bariatric Surgery is Associated with a Reduced Risk of Mortality in Morbidly Obese Patients with a History of Major Cardiovascular Events

2012 ◽  
Vol 78 (6) ◽  
pp. 685-692 ◽  
Author(s):  
Rebecca J. Johnson ◽  
Brent L. Johnson ◽  
Dawn W. Blackhurst ◽  
Eric S. Bour ◽  
William S. Cobb Iv ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Cardiovascular Event ◽  
Cardiovascular Events ◽  
Event History ◽  
Morbidly Obese ◽  
Risk Of Mortality ◽  
All Cause Mortality ◽  
History Of ◽  
Bariatric Patients

Although the safety of bariatric surgery in patients with established cardiovascular disease has been demonstrated, little is known about the mid- to long-term survival of these patients after surgery. We conducted a retrospective cohort study of bariatric surgical patients (n = 349) compared with morbidly obese surgical controls (n = 903). Data were obtained on all patients 40 to 79 years of age, from 1996 to 2008, with a diagnosis code of morbid obesity, a primary surgical procedure of interest, and a cardiovascular event history. Data sources were the statewide South Carolina UB92 inpatient hospitalization database and death records. The primary outcome was all-cause mortality. A total of 349 bariatric and 903 control patients with cardiovascular event histories were identified. Among bariatric patients, 19 deaths occurred in 986 person-years of follow-up versus 150 deaths among controls in 3138 person-years of follow-up. Unadjusted all-cause mortality was estimated at 7 ± 2 per cent at 5 years in bariatric patients compared with 19 ± 2 per cent ( P < 0.001) in controls. Adjusting for age, comorbidities, and event history, the relative risk of mortality was reduced by 40 per cent in bariatric patients compared with controls [hazard ratios (95% confidence interval): 0.60 (0.36, 0.99)]. In patients with a history of cardiovascular events, bariatric surgery is associated with a significantly decreased risk of all-cause mortality.

scholarly journals Development of De Novo Diabetes in Long-term Follow-up after Bariatric Surgery

2017 ◽  
Vol 13 (10) ◽  
pp. S11
Author(s):  
Zubaidah Nor Hanipah ◽  
Suriya Punchai ◽  
Stacy Brethauer ◽  
Philip Schauer ◽  
Ali Aminian
Keyword(s):  
Bariatric Surgery ◽  
De Novo ◽  
Long Term Follow Up

Lithium and recurrence in a long-term follow-up of bipolar affective disorder

1997 ◽  
Vol 27 (2) ◽  
pp. 281-289 ◽  
Author(s):  
W. CORYELL ◽  
G. WINOKUR ◽  
D. SOLOMON ◽  
T. SHEA ◽  
A. LEON ◽  
...  
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Treatment Decisions ◽  
First Year ◽  
Drug Status ◽  
Prophylactic Effect ◽  
Long Term Follow Up ◽  
Physiological Differences

Background. Though previous studies have clearly shown that lithium affords prophylaxis in bipolar affective disorder, these studies have not demonstrated the persistence of this prophylactic effect beyond the first year of recovery.Methods. One hundred and eighty-one patients with bipolar affective disorder recovered during 5 years of semi-annual follow-up. After 8 weeks of recovery, 139 were taking lithium prophylaxis and 42 were not. Analyses used drug status (lithium v. no-lithium) as a censoring variable to compare these two groups by interval-specific probabilities of recurrence.Results. Recurrence was initially less likely in the lithium group but interval-specific probabilities of recurrence did not consistently favour either group after the first 32 weeks of recovery.Conclusions. Biases in treatment decisions may have both reduced the size and altered the specificity of the lithium effects seen here. Nevertheless, the apparent transience of lithium prophylactic effects is unexplained and may reflect important, physiological differences between relapse and recurrence. This possibility invites a controlled lithium discontinuation study, with gradual taper, of patients who have had at least 8 months of sustained euthymia.

scholarly journals Chew and spit (CHSP) in bariatric patients: a case series

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Phillip Aouad ◽  
Kristin Stedal ◽  
Gro Walø-Syversen ◽  
Phillipa Hay ◽  
Camilla Lindvall Dahlgren
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Disordered Eating ◽  
Weight Loss Surgery ◽  
Eating Pathology ◽  
Post Surgery ◽  
Significant Depression ◽  
Bariatric Patients ◽  
Clinically Significant

Abstract Background Studies into the disordered eating behaviour of chew and spit have alluded to several cohorts more likely to engage in the behaviour, one such group being bariatric surgery candidates and patients. Weight-loss surgery candidates have received little to no attention regarding engaging in chew and spit behaviour. Changes in pre- and post- surgery eating pathology related to chew and spit behaviour has yet to be explored and described in academic literature. Case presentation The current study reports on three cases of individual women, aged 30, 35, and 62 respectively, who indicated engagement in chew and spit. All three cases underwent bariatric surgery (two underwent gastric bypass, one underwent vertical sleeve gastrectomy). Eating pathology—including chew and spit behaviour, anxiety and depression, and adherence to the Norwegian nutritional guidelines were examined pre-operatively and post-operatively (one and two-year follow-up). At baseline (pre-surgery), two participants reported that they engaged in chew and spit, compared to one patient post-surgery. All three cases reported that they, to at least some extent, adhered to dietary guidelines post-surgery. Subjective bingeing frequency appeared to be relatively low for all three cases, further declining in frequency at one-year follow-up. At baseline, one participant reported clinically significant depression and anxiety, with no clinically significant depression or anxiety reported at follow-ups in participants that chew and spit. Conclusions The current study provides a starting point for the exploration of chew and spit as a pathological symptom of disordered eating in bariatric patients. It highlights the need to further explore chew and spit before and after weight-loss surgery.

A quality-improvement optimization pilot of BariFit, a mobile health intervention to promote physical activity after bariatric surgery

2020 ◽  
Author(s):  
Predrag Klasnja ◽  
Dori E Rosenberg ◽  
Jing Zhou ◽  
Jane Anau ◽  
Anirban Gupta ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bariatric Surgery ◽  
Weight Loss ◽  
Quality Improvement ◽  
Mobile Health ◽  
Text Messages ◽  
First Year ◽  
Mhealth Intervention ◽  
Steps Per Day ◽  
Bariatric Patients

Abstract Bariatric surgery is the most effective treatment for severe obesity (body mass index &gt;40), helping individuals lose, on average, 25%–29% of their body weight over the first year. However, many patients begin to plateau and regain weight within 12–24 months, and 20% of patients begin to regain weight within 6 months postsurgery. As physical activity (PA) is an important predictor of weight loss and maintenance postsurgery, there is a need for scalable, effective lifestyle interventions to help bariatric patients increase PA in order to maximize their weight loss and maintenance. To assess feasibility of using mobile health (mHealth) tools to support PA postsurgery, we conducted a quality-improvement optimization pilot of BariFit, an mHealth intervention that combines commercial devices and custom text messages. Fifty-one bariatric patients enrolled in a 16-week optimization pilot of BariFit. To assess feasibility, pre–post changes in PA were assessed using activPAL. In addition, the pilot randomized, using a 2 × 2 factorial design, two adaptive approaches to daily step goals (variable and 60th percentile goals) and provision of rest days (yes/no), and microrandomized provision of SMS-delivered activity suggestions five times a day for each participant. Adherence to using study equipment was over 95% at 16 weeks. Participants increased PA by 1,866 steps from baseline to end-of-study (p &lt; .007). Participants who received variable step goals averaged 1,141 more steps per day (p = .096) than those who received 60th percentile goals. Activity suggestions had no effect. mHealth interventions are feasible for supporting PA postbariatric surgery.

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