scholarly journals Adaptation of the method of pulse wave velocity measurement for screening examinations in outpatient practice

2019 ◽  
Vol 10 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Yulia V. Tkachenko ◽  
Irina D. Strazhesko ◽  
Evgeniy N. Borisov ◽  
Alina G. Plisiuk ◽  
Iana A. Orlova
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Supine Position ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Clinical Manifestations ◽  
Sitting Position ◽  
Oscillometric Method ◽  
Wall Stiffness ◽  
Outpatient Practice

Background. Estimation of the parameters of arterial stiffness allows one to make conclusions about the development of CVD long before clinical manifestations of the target organ damage. The determination of the pulse wave velocity (PWV) is the «gold standard» for the arterial wall stiffness assessment. The oscillometric method of PWV measurement has a number of advantages (convenience and high speed) over the most common «two-point» techniques. Objective. The purpose of this work was to adapt the PWV measurement using the oscillometric method for screening outpatient examinations. Using a BPLab Vasotens diagnostic oscillometric system (Russia), PWV was measured in 152 patients, and a formula was obtained for recalculating PWV values in the supine position on the basis of PWV values in the sitting position. Methods. Using a BPLab Vasotens diagnostic system, PWV was measured in 152 patients, and a formula was derived for recalculating PWV values in the supine position on the basis of PWV values in the sitting position. Results. Measuring aortal PWV in the sitting position gave an opportunity of a simultaneous study of the central and peripheral BP parameters and the arterial wall stiffness. The obtained data may be used during patients’ screening in the outpatient setting. Conclusion. The use of the screening procedure for the PWV measurement in the outpatient practice will allow concluding on the CVD development long before clinical manifestations of the target organs damage and will rid the patient of a possibility of a wrong estimation of their cardiovascular risk.

ARTERIAL WALL STIFFNESS AND THE RISK OF ATHEROSCLEROSIS IN EGYPTIAN PATIENTS WITH OVERT AND SUBCLINICAL HYPOTHYROIDISM

2020 ◽  
Vol 26 (2) ◽  
pp. 161-166
Author(s):  
Shrook Mousa ◽  
Afaf Hemeda ◽  
Hamed Ghorab ◽  
Alaa Abdelhamid ◽  
Aasem Saif
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Subclinical Hypothyroidism ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Density Lipoprotein ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Overt Hypothyroidism ◽  
Wall Stiffness

Objective: Hypothyroidism is associated with an increased risk of atherosclerosis. Pulse wave velocity (PWV) is an index of arterial wall stiffness widely used for noninvasive assessment of early atherosclerosis. We assessed PWV in Egyptian patients with hypothyroidism. Methods: The study included 100 Egyptian females aged 18 to 55 years. They were classified into three groups: group I, 40 women with overt hypothyroidism; group II, 40 women with subclinical hypothyroidism; and group III, 20 euthyroid women as a control group. The three groups were age matched. Doppler ultrasonography was used to calculate the heart-femoral PWV. Results: PWV was significantly higher in women with overt and subclinical hypothyroidism as compared with the control group (9.55 ± 1.81 m/s and 9.30 ± 1.28 m/s, respectively vs. 7.82 ± 2.14 m/s; P<.001 and <.01, respectively). There was a positive correlation between thyroid-stimulating hormone (TSH) and PWV in women with overt hypothyroidism and in those with subclinical hypothyroidism ( P<.05 for both). Multivariate regression analysis showed that age and diastolic blood pressure were independent determinants of PWV in women with overt and subclinical hypothyroidism ( P<.01 for all). TSH was also an independent determinant of PWV in both groups ( P<.05 for both). Conclusion: PWV is significantly higher in Egyptian women with overt and subclinical hypothyroidism as compared with normal control subjects. This denotes early increase in arterial wall stiffness in patients with hypothyroidism, even in the subclinical phase. The positive correlation between PWV and TSH in both groups of patients suggests that the risk of atherosclerosis is proportionate to the severity of hypothyroidism. Abbreviations: ABI = ankle/brachial index; baPWV = brachial-ankle pulse wave velocity; BP = blood pressure; CIMT = carotid intima-media thickness; ECG = electrocardiogram; FT4 = free thyroxine; HDL = high-density lipoprotein; hfPWV = heart-femoral pulse wave velocity; LDL = low-density lipoprotein; PTT = pulse transit time; PWV = pulse wave velocity; SCH = subclinical hypothyroidism; TSH = thyroid-stimulating hormone

MEASUREMENT OF PARAMETERS CHARACTERIZING EARLY VASCULAR AGING WITH THE USE OF OSCILLOMETRIC METHOD DURING SPACE FLIGHT

2021 ◽  
Vol 55 (6) ◽  
pp. 23-27
Author(s):  
E.S. Luchitskaya ◽  
◽  
I.I. Funtova ◽  
J. Tank ◽  
H. Reuter ◽  
...  
Keyword(s):  
At Risk ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Space Flight ◽  
Pulse Wave ◽  
Vascular Wall ◽  
Vascular Aging ◽  
Threshold Values ◽  
Oscillometric Method ◽  
Cardiac Health

The article covers the studies of the vascular wall functioning in cosmonauts using the data of pulse wave velocity as a biomarker of early vascular aging. The investigations were performed with the use of device Mobilograph twice before launch, every 30 days of 6-month ISS missions and on days 4 and 8 of recovery. Pulse wave velocity has never exceeded threshold values suggesting that participation in low-Earth orbital missions does not put at risk cardiac health threatening with vascular pathologies. Yet, the conclusion can be premature given the limited potentialities of the method and hardware used in the investigation.

scholarly journals Relationship of arterial wall parameters to cardiovascular risk factors and cardiovascular risk assessed by SCORE system

Medicina ◽  
2007 ◽  
Vol 43 (7) ◽  
pp. 529 ◽  
Author(s):  
Milda Kovaitė ◽  
Žaneta Petrulionienė ◽  
Ligita Ryliškytė ◽  
Jolita Badarienė ◽  
Alma Čypienė ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness ◽  
Flow Mediated Dilatation

Objective. To investigate the relationship of arterial wall parameters (flow-mediated dilatation of the brachial artery, augmentation index, pulse wave velocity, stiffness index, carotid intima-media thickness) to conventional cardiovascular risk factors and cardiovascular risk assessed by SCORE system. Material and methods. A total of 209 subjects aged 40–65 years without clinically overt cardiovascular disease were examined. Parameters of arterial stiffness were obtained by two methods: augmentation index and carotid-radial pulse wave velocity by applanation tonometry and stiffness index by the means of finger photoplethysmography. Flow-mediated dilatation of the brachial artery, reflecting endothelial function, and carotid intima-media thickness was determined using a high-resolution B-mode ultrasonography. Results. Age and the presence of diabetes strongly influenced all parameters of the arterial wall (diabetes was not independent predictor when evaluating augmentation index). Mean arterial pressure and gender were independent predictors for arterial stiffness parameters – carotid-radial pulse wave velocity and augmentation index. Flow-mediated dilatation was strongly dependent on the diameter of the brachial artery, age, and body mass index. Using logistic regression, it was found that pulse wave velocity (P=0.014), intima-media thickness (P=0.004), and flow-mediated dilatation (P=0.020) were important parameters dividing subjects to the groups of increased (³5%) and low (<5%) cardiovascular risk assessed by SCORE system. The cutoff values for intima-media thickness and pulse wave velocity were 0.078 cm and 8.95 m/s, respectively. Conclusions. Arterial wall parameters are closely associated with conventional risk factors; they are influenced by age and the presence of diabetes. Arterial stiffness parameters are also influenced by mean arterial pressure; high-density lipoprotein cholesterol has influence on carotid intima-media thickness. Cutoff values for carotid intima-media thickness and carotid-radial pulse wave velocity could help to discriminate patients with increased cardiovascular risk.

scholarly journals Blood pressure level and arterial stiffness parameters role in prediction of the antihypertensive therapy efficacy escape phenomenon

2018 ◽  
Vol 15 (2) ◽  
pp. 49-54
Author(s):  
O O Mikhailova ◽  
E M Elfimova ◽  
A Yu Litvin ◽  
A N Rogoza
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Antihypertensive Therapy ◽  
Pulse Wave ◽  
Stiffness Index ◽  
Wall Stiffness ◽  
Artery Stiffness ◽  
Group 1

The aim of the study was to evaluate blood pressure (BP) level and vessel wall stiffness parameters role in antihypertensive therapy (AHT) escape phenomena development on the background of primarily effective AHT use. Materials and methods. Data from 102 patients with arterial hypertension level 1-3, stage I-II were analyzed. All patients underwent individual AHT adjustment for 2-3 weeks (adjustment period). At the end of the adjustment period the therapy effectiveness was evaluated with clinical BP measurement (target BP values less than 140/90 mm hg) and 24-hour BP monitoring (target daily BP values less than 130/80 mm hg). The study included only those patients who reached target clinical and daily BP values on the background of 2-3 antihypertensive drugs use at the end of the adjustment period. At the beginning of the observation period after effective AHT was used carotid-femoral pulse wave velocity was evaluated with applanation tonometry. For the purpose of timely escape phenomena diagnosis clinical BP measurement and 24-hour BP monitoring were performed in 1, 3, and 6 months after the trial start in all patients. Results. After 6 months of observation patients were divided in 2 groups: group 1 included 34 patients with AHT escape phenomena, group 2 - 68 patients with stable, controlled AH. In group 1 on the background of effective AHT use at the beginning of observation higher levels of following measures were observed: clinical systolic BP - SBP (125.2±11.3 mm hg vs 119.7±11.7 mm hg, p=0.021), daily SBP (128.0±3.3 mm hg vs 121.2±7.4 mm hg, p=0.000), daily average SBP (131.6±4.9 mm hg vs 125.3±8.5 mm hg, р=0.000), night average SBP (120.4±8.5 mm hg vs 111.8±8.6 mm hg, р=0.000), daily pulse BP 50.2±4.8 mm hg vs 44.2±7.6 mm hg, p=0.000), daily mean brachial artery stiffness index - ASI (161.9±28.3 mm hg vs 142.2±24.5 mm p=0.000), carotid-femoral pulse wave velocity (11.6±2.5 m/s vs 10.5±2.3 m/s, p=0.029). In single-factor logistic regression models all these measures were shown to have predictive value in AHT escape phenomena development. According to multifactor logistic regression analysis that included carotid-femoral pulse wave velocity more than 10.8 m/s, daily mean ASI>137, daily SBP>124 mm hg, and daily pulse BP>46 mm hg, the only independent predictor on the background of effective AHT at the beginning of the observation was daily SBP>124 mm hg (odds ratio 19.1, 95% confidence interval 3.6-101.8; p=0.0004). Conclusion. BP level and artery stiffness index measured on the background of effective AHT at the beginning of the observation are predictors for escape phenomena development and can be used for effectiveness and required frequency of therapy management prognosis.

P9.02EVALUATION OF PULSE WAVE VELOCITY AND AUGMENTATION INDEX IN SUPINE AND SITTING POSITION

2009 ◽  
Vol 3 (4) ◽  
pp. 167
Author(s):  
J. Nuernberger ◽  
R. Michalski ◽  
A. Opazo Saez ◽  
A. Kribben
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Sitting Position

scholarly journals Plasma levels of the arterial wall protein fibulin-1 are associated with carotid-femoral pulse wave velocity: a cross-sectional study

2013 ◽  
Vol 12 (1) ◽  
pp. 107 ◽  
Author(s):  
Esben Laugesen ◽  
Pernille Høyem ◽  
Jens Christiansen ◽  
Søren Knudsen ◽  
Klavs Hansen ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Plasma Levels ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional
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