scholarly journals Significance of the left ventricular ejection fraction in diagnosis of heart failure

2018 ◽  
Vol 20 (1) ◽  
pp. 68-74
Author(s):  
Yu S Malov ◽  
I I Yarovenko

Left ventricular ejection fraction, not being an indicator of contractility, is widely used in practice for the diagnosis of heart failure. It reflects only a change in volume of the left ventricle. It was found that the ejection fraction is not so much dependent on the shock and final diastolic volume as on the final systolic volume. An inverse relationship was found between the left ventricular ejection fraction and the end systolic volume. The larger the end systolic volume, the lower the ejection fraction. High final ejection fraction corresponds to a small terminal systolic volume of the left ventricle. The ejection fraction, representing the ratio of the impact volume to the final diastolic, reflects structural changes in the left ventricle. The more these disorders, the lower the fraction of the ejection of the left ventricle. Its connection with heart failure is realized indirectly through structural restructuring of the myocardium. Low ejection fraction indicates severe damage to the myocardium and unfavorable prognosis for the patient. The empirically established emission fraction did not receive a scientific justification for the regulatory framework. According to the symmetrical approach to the study of a heart, the volume ratio of the left ventricle represents a golden proportion (0,618). Hence, the ideal left ventricular ejection fraction is 62 %, but not 50-80 %, as is customary. An increase or decrease in the ejection fraction indicates a change in the volume of the left ventricle. The clinical morphological similarity of patients with heart failure, classified according to functional classes and size of the ejection fraction, was revealed, which casted doubt on the introduction of the classification of heart failure by the size of the ejection fraction into practice.

2011 ◽  
pp. 62-70
Author(s):  
Lien Nhut Nguyen ◽  
Anh Vu Nguyen

Background: The prognostic importance of right ventricular (RV) dysfunction has been suggested in patients with systolic heart failure (due to primary or secondary dilated cardiomyopathy - DCM). Tricuspid annular plane systolic excursion (TAPSE) is a simple, feasible, reality, non-invasive measurement by transthoracic echocardiography for evaluating RV systolic function. Objectives: To evaluate TAPSE in patients with primary or secondary DCM who have left ventricular ejection fraction ≤ 40% and to find the relation between TAPSE and LVEF, LVDd, RVDd, RVDd/LVDd, RA size, severity of TR and PAPs. Materials and Methods: 61 patients (36 males, 59%) mean age 58.6 ± 14.4 years old with clinical signs and symtomps of chronic heart failure which caused by primary or secondary DCM and LVEF ≤ 40% and 30 healthy subject (15 males, 50%) mean age 57.1 ± 16.8 were included in this study. All patients and controls were underwent echocardiographic examination by M-mode, two dimentional, convensional Dopler and TAPSE. Results: TAPSE is significant low in patients compare with the controls (13.93±2.78 mm vs 23.57± 1.60mm, p<0.001). TAPSE is linearly positive correlate with echocardiographic left ventricular ejection fraction (r= 0,43; p<0,001) and linearly negative correlate with RVDd (r= -0.39; p<0.01), RVDd/LVDd (r=-0.33; p<0.01), RA size (r=-0.35; p<0.01), TR (r=-0.26; p<0.05); however, no correlation was found with LVDd and PAPs. Conclusions: 1. Decreased RV systolic function as estimated by TAPSE in patients with systolic heart failure primary and secondary DCM) compare with controls. 2. TAPSE is linearly positive correlate with LVEF (r= 0.43; p<0.001) and linearly negative correlate with RVDd (r= -0.39; p<0.01), RVDd/LVDd (r=-0.33; p<0.01), RA size (r=-0.35; p<0.01), TR (r=-0.26; p<0.05); however, no correlation is found with LVDd and PAPs. 3. TAPSE should be used routinely as a simple, feasible, reality method of estimating RV function in the patients systolic heart failure DCM (primary and secondary).


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