Factors Affecting Maternal Mortality in Pregnant Women With Sickle Cell Disease in Ahvaz, Iran: A 10-Year Epidemiological Study

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Razieh Mohammadjafari ◽  
Roushan Nikbakht ◽  
Mahdis Vakili ◽  
Pedram Yavari ◽  
Negin Gholami
Keyword(s):  
Sickle Cell Disease ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Epidemiological Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
Factors Affecting

O945 Maternal morbidity in pregnant women with sickle cell disease

2009 ◽  
Vol 107 ◽  
pp. S362-S362
Author(s):  
K. Tosta ◽  
R. Nomura ◽  
A. Igai ◽  
G. Fonseca ◽  
S. Gualandro ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Maternal Morbidity ◽  
Cell Disease

scholarly journals Factors affecting prepubertal growth in homozygous sickle cell disease.

1996 ◽  
Vol 74 (6) ◽  
pp. 502-506 ◽  
Author(s):  
A Singhal ◽  
J Morris ◽  
P Thomas ◽  
G Dover ◽  
D Higgs ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cell Disease ◽  
Factors Affecting ◽  
Homozygous Sickle Cell Disease

P357 Perinatal and maternal outcomes in pregnant women with sickle cell disease and sickle cell trait

2009 ◽  
Vol 107 ◽  
pp. S516-S516
Author(s):  
K. Tosta ◽  
R. Nomura ◽  
A. Igai ◽  
G. Fonseca ◽  
S. Gualandro ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Sickle Cell Trait ◽  
Maternal Outcomes ◽  
Cell Disease

scholarly journals Iron stores in pregnant women with sickle cell disease: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e026497 ◽  
Author(s):  
Desmond Aroke ◽  
Benjamin Momo Kadia ◽  
Tsi Njim
Keyword(s):  
Systematic Review ◽  
Sickle Cell Disease ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Cell Disease ◽  
Deficiency Anaemia

IntroductionSickle cell disease (SCD) is the most common inherited disease worldwide. The greatest disease burden is seen in sub-Saharan Africa. Early diagnosis and improved care of people living with SCD have led to an increase in the number of women with SCD reaching the reproductive age. Iron deficiency anaemia remains the most common cause of anaemia in pregnancy, affecting 51%–63% of pregnancies in Africa. However, the unavailability of guidelines on supplementation of iron in this pregnant subpopulation often leaves clinicians in a fix. We propose to conduct the first systematic review and possibly a meta-analysis on the prevalence, associated factors and maternal/fetal outcomes of iron deficiency anaemia among pregnant women with SCD.Methods and analysisWe will search the following electronic databases for studies on the iron status of pregnant women with SCD: PubMed, MEDLINE, EMBASE, Google Scholar, African Journals Online, African Index Medicus, Popline and the Cochrane Library. After the selection of eligible studies from the search output, review of full text, data extraction and data synthesis will be performed. Studies obtained from the review shall be evaluated for quality, risk of bias and heterogeneity. Appropriate statistical methods shall be used to pool prevalence estimates for matching studies globally and in subpopulations. This protocol has been reported as per the 2015 guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols.Ethics and disseminationThere is no requirement for ethical approval as the proposed study will use published data. The findings of this study will be published in a peer-reviewed journal and will be presented at conferences.Trial registration numberCRD42018109803.

Transfusion practices in the care of pregnant women with sickle cell disease in Ouagadougou

2019 ◽  
Vol 147 (3) ◽  
pp. 363-367
Author(s):  
Hyacinthe Zamané ◽  
Fabienne Sanou ◽  
Sibraogo Kiemtoré ◽  
Dantola Paul Kain ◽  
Arnaud Kiswendsida Sawadogo ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Cell Disease

Psychological help for pregnant women with sickle cell disease

2009 ◽  
Vol 19 (7) ◽  
pp. 26-29 ◽  
Author(s):  
Veronica Thomas ◽  
Heather Rawle ◽  
Jo Howard ◽  
Mina Abedian ◽  
Neill Westerdale ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Psychological Help ◽  
Cell Disease

Prevalence of Sickle Cell Disease in Pregnant Women and Neonates in Africa

2018 ◽  
Author(s):  
Dr.Callixte Yadufashije ◽  
George Bahati Sangano ◽  
Rebero Samuel
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Cell Disease

Physiologic observations of pregnant women undergoing prophylactic erythrocytapheresis for sickle cell disease

Transfusion ◽  
1991 ◽  
Vol 31 (1) ◽  
pp. 59-62 ◽  
Author(s):  
W Lee ◽  
J Werch ◽  
R Rokey ◽  
J Pivarnik ◽  
J Miller
Keyword(s):  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Cell Disease

Folic Acid Supplementation and Twin Pregnancy in Patients with Sickle Cell Disease.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 3744-3744
Author(s):  
Samir K. Ballas ◽  
Jason Baxter ◽  
Gaye Riddick
Keyword(s):  
Folic Acid ◽  
Sickle Cell Disease ◽  
Pregnant Women ◽  
Sickle Cell ◽  
Folic Acid Supplementation ◽  
Multiple Births ◽  
Cell Disease ◽  
Folate Supplementation ◽  
Acid Supplementation ◽  
Twin Pregnancies

Abstract Patients with sickle cell disease (SCD) usually take 1mg of folic acid daily. The rationale for this approach is to maintain effective erythropoiesis with a stable hemoglobin level. Other potential advantages of folate therapy in patients with SCD include the prevention of hyperhomocysteinemia that may predispose to thrombotic events, which, in turn, may lead to painful episodes. Moreover, folate supplementation during pregnancy is known to prevent neural tube defects in infants. The major disadvantage of folate supplementation in patients with SCD is that it may mask vitamin B12 deficiency. Another controversial effect of folic acid supplementation pertains to its potential effect on the number of twins coming to term. We reviewed our database on patients with SCD to determine the effect, if any, of folic acid supplementation on twin pregnancies. The data were collected prospectively since 1981. All patients routinely took 1.0 mg of folic acid orally on a daily basis. Random testing of the level of folic acid in the steady state in women with SCD including those who became pregnant showed increased levels to > 20ng/ml (Normal range: 3.0–18.0 ng/ml) in most patients. Pregnant patients also took additional perinatal vitamins that also contained folic acid. We selected those pregnant patients in whom the outcome of pregnancy was either a liveborn or stillborn at or after 20 weeks’ gestation. We found that 46 patients with SCD became pregnant 60 times between 1981 and 2002 and who met the defined criteria mentioned above. The average maternal age at delivery was 26 years. Fifty-six pregnancies (93%) ended in liveborn and the remaining four (7%) in intrauterine fetal death. Five pregnancies (8.3%) resulted in the delivery of twins. This is a significantly higher rate of multiple births compared to other pregnant women. The reported rate of multiple births is between 0.34 and 1.1% both in Black and Caucasian women respectively. All twin births were dizygotic in nature. Patients with SCD take higher amounts of folic acid on a regular basis for a longer period of time before and after pregnancy than other pregnant women. This may explain why twin pregnancies are higher in these patients. The reason why folate therapy is associated with twinning is unknown at the present. Further studies may clarify the pathogenetic pathway of this phenomenon.

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