scholarly journals Design and Implementation of High Precision Synchronization Controller for Gated Imaging

CONVERTER ◽  
2021 ◽  
pp. 489-497
Author(s):  
Xiaoxuan Hu, Et al.

In this paper, we have designed a high-precision synchronization controller for gated imaging. The design scheme is proposed according to the semiconductor laser arrays overall range-gated imaging system composition and working principle. The programming of control logic is illustrated in detail from the main time counter, mode control logic, key control decoder, pulse generator, automatic frequency generator and display control. Finally, a synchronization controller with precision of 80 ns and frequency of 12 khz was developed. The whole system joint debugging test shows that the indicators of the synchronization controller have reached the expected goal, and have met the current technical requirements of gated imaging within 3 km in the atmospheric environment.

Author(s):  
Yanzhu Yue ◽  
Xin Li ◽  
Youdong Zhang ◽  
Aibin He

Abstract Mapping holistic cell behaviors sculpting mammalian heart has been a goal, but so far only successes in transparent invertebrates and lower vertebrates. Using a live-imaging system comprising a customized vertical light-sheet microscope equipped with a culture module, a heartbeat-gated imaging strategy, and a digital image processing framework, we realized imaging of developing mouse hearts with uninterrupted cell lineages for up to 1.5 days. Four-dimensional landscapes of cell behaviors revealed a blueprint for ventricle chamber formation in which biased outward migration of outermost cardiomyocytes coupled with cell intercalation and horizontal division. The trabeculae, an inner muscle architecture, was developed through early fate segregation and transmural cell arrangement involving both oriented cell division and directional migration. Thus, live-imaging reconstruction affords a transformative means for deciphering mammalian organogenesis.


2021 ◽  
Vol 6 (52) ◽  
pp. eabd2813
Author(s):  
Ben Wang ◽  
Kai Fung Chan ◽  
Ke Yuan ◽  
Qianqian Wang ◽  
Xianfeng Xia ◽  
...  

High-precision delivery of microrobots at the whole-body scale is of considerable importance for efforts toward targeted therapeutic intervention. However, vision-based control of microrobots, to deep and narrow spaces inside the body, remains a challenge. Here, we report a soft and resilient magnetic cell microrobot with high biocompatibility that can interface with the human body and adapt to the complex surroundings while navigating inside the body. We achieve time-efficient delivery of soft microrobots using an integrated platform called endoscopy-assisted magnetic actuation with dual imaging system (EMADIS). EMADIS enables rapid deployment across multiple organ/tissue barriers at the whole-body scale and high-precision delivery of soft and biohybrid microrobots in real time to tiny regions with depth up to meter scale through natural orifice, which are commonly inaccessible and even invisible by conventional endoscope and medical robots. The precise delivery of magnetic stem cell spheroid microrobots (MSCSMs) by the EMADIS transesophageal into the bile duct with a total distance of about 100 centimeters can be completed within 8 minutes. The integration strategy offers a full clinical imaging technique–based therapeutic/intervention system, which broadens the accessibility of hitherto hard-to-access regions, by means of soft microrobots.


2019 ◽  
Vol 39 (4) ◽  
pp. 0412010
Author(s):  
程虎 Cheng Hu ◽  
李微 Li Wei ◽  
郭文平 Guo Wenping ◽  
杨克成 Yang Kecheng

2011 ◽  
Vol 38 (1) ◽  
pp. 0109001
Author(s):  
韩宏伟 Han Hongwei ◽  
张晓晖 Zhang Xiaohui ◽  
葛卫龙 Ge Weilong

2016 ◽  
Vol 45 (7) ◽  
pp. 0726003
Author(s):  
游瑞蓉 You Ruirong ◽  
王新伟 Wang Xinwei ◽  
周 燕 Zhou Yan

2010 ◽  
Vol 18 (20) ◽  
pp. 21147 ◽  
Author(s):  
ChingSeong Tan ◽  
Gerald Seet ◽  
Andrzej Sluzek ◽  
Xin Wang ◽  
Chai Tong Yuen ◽  
...  

1972 ◽  
Vol 5 (6) ◽  
pp. 233-237
Author(s):  
C R Burrows ◽  
L Lowe

This paper presents some preliminary results of an experimental investigation of a novel fluidic pulse generator. The experiments were performed to establish the useful working range of the device, and to examine the feasibility of constructing a variable frequency generator.


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