scholarly journals Synthesis of 3-trifluoromethyl-3-pyrimidinyl diazirines as photoreactive amino acid analogs

2019 ◽  
Author(s):  
Jackson G. Cacioppo
Keyword(s):  
Amino Acid ◽  
Amino Acid Analogs

PUROMYCIN. SYNTHETIC STUDIES. VII. PARTIAL SYNTHESIS OF AMINO ACID ANALOGS

1954 ◽  
Vol 76 (10) ◽  
pp. 2838-2838 ◽  
Author(s):  
B. R. Baker ◽  
Joseph P. Joseph ◽  
James H. Williams
Keyword(s):  
Amino Acid ◽  
Partial Synthesis ◽  
Amino Acid Analogs ◽  
Synthetic Studies

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells

1988 ◽  
Vol 8 (11) ◽  
pp. 4736-4744
Author(s):  
D D Mosser ◽  
N G Theodorakis ◽  
R I Morimoto
Keyword(s):  
Protein Synthesis ◽  
Amino Acid ◽  
Heat Shock ◽  
Gene Transcription ◽  
Elevated Temperatures ◽  
Binding Activity ◽  
Heat Shock Gene ◽  
Hsp70 Gene ◽  
Heat Shock Element ◽  
Amino Acid Analogs

Activation of human heat shock gene transcription by heat shock, heavy metal ions, and amino acid analogs required the heat shock element (HSE) in the HSP70 promoter. Both heat shock- and metal ion-induced HSP70 gene transcription occurred independently of protein synthesis, whereas induction by amino acid analogs required protein synthesis. We identified a HSE-binding activity from control cells which was easily distinguished by a gel mobility shift assay from the stress-induced HSE-binding activity which appeared following heat shock or chemically induced stress. The kinetics of HSP70 gene transcription paralleled the rapid appearance of stress-induced HSE-binding activity. During recovery from heat shock, both the rate of HSP70 gene transcription and stress-induced HSE-binding activity levels declined and the control HSE-binding activity reappeared. The DNA contacts of the control and stress-induced HSE-binding activities deduced by methylation interference were similar but not identical. While stable complexes with HSE were formed with extracts from both control and stressed cells in vitro at 25 degrees C, only the stress-induced complex was detected when binding reactions were performed at elevated temperatures.

Behavioral effects of alpha-alkylated amino acid analogs in the C57BL/6J mouse

2013 ◽  
Vol 252 ◽  
pp. 432-438 ◽  
Author(s):  
Ajinkya Sase ◽  
Hans Brückner ◽  
Harald Höger ◽  
Arnold Pollak ◽  
Gert Lubec
Keyword(s):  
Amino Acid ◽  
Behavioral Effects ◽  
Amino Acid Analogs

Electrochemical properties of tyrosine phenoxy and tryptophan indolyl radicals in peptides and amino acid analogs

1991 ◽  
Vol 95 (8) ◽  
pp. 3416-3419 ◽  
Author(s):  
Michael R. DeFelippis ◽  
C. P. Murthy ◽  
F. Broitman ◽  
D. Weinraub ◽  
M. Faraggi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Electrochemical Properties ◽  
Amino Acid Analogs
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