scholarly journals THC mediated tolerance to the diuretic effects of cannabinoids & kappa opioids in mice

2014 ◽  
Author(s):  
Viraj A. Parge
Keyword(s):  
Kappa Opioids

Effects of kappa opioids in the inflamed rat colon

Pain ◽  
1999 ◽  
Vol 79 (2) ◽  
pp. 175-185 ◽  
Author(s):  
N J. Sengupta ◽  
Anne Snider ◽  
Xin Su ◽  
F G. Gebhart
Keyword(s):  
Rat Colon ◽  
Kappa Opioids

Anti-inflammatory effects of kappa-opioids in adjuvant arthritis

Life Sciences ◽  
1995 ◽  
Vol 57 (4) ◽  
pp. 371-378 ◽  
Author(s):  
Judith S. Walker ◽  
C.Rolfe Howlett ◽  
Vim Nayanar
Keyword(s):  
Adjuvant Arthritis ◽  
Kappa Opioids ◽  
Anti Inflammatory

Kappa Opioids

1994 ◽  
Vol 17 (5) ◽  
pp. 403-416 ◽  
Author(s):  
Frank C. Tortella ◽  
Mark A. DeCoster
Keyword(s):  
Kappa Opioids

Pharmacological analysis of the rate-decreasing effects of mu and kappa opioids in pigeons

1994 ◽  
Vol 113 (3-4) ◽  
pp. 457-462 ◽  
Author(s):  
Adande J. Mattox ◽  
Mitchell J. Picker ◽  
Linda A. Dykstra
Keyword(s):  
Kappa Opioids ◽  
Pharmacological Analysis

Role of kappa-opioids and neurokinin 1 receptor interactions on visceral nociception in a rat model

2003 ◽  
Vol 124 (4) ◽  
pp. A612
Author(s):  
Tobias Liebregts ◽  
Birgit Adam ◽  
Anton Bertel ◽  
Venus Eishabady ◽  
Guido Gerken ◽  
...  
Keyword(s):  
Rat Model ◽  
Neurokinin 1 Receptor ◽  
Kappa Opioids ◽  
Visceral Nociception ◽  
Receptor Interactions ◽  
Neurokinin 1

Kappa–opioids produce significantly greater analgesia in women than in men

1996 ◽  
Vol 2 (11) ◽  
pp. 1248-1250 ◽  
Author(s):  
Robert W. Gear ◽  
Christine Miaskowski ◽  
Newton C. Gordon ◽  
Steven M. Paul ◽  
Philip H. Heller ◽  
...  
Keyword(s):  
Kappa Opioids

scholarly journals Kappa opioids promote the proliferation of astrocytes via Gβγ and β-arrestin 2-dependent MAPK-mediated pathways

2008 ◽  
Vol 107 (6) ◽  
pp. 1753-1765 ◽  
Author(s):  
Gregory P. McLennan ◽  
Alexi Kiss ◽  
Mayumi Miyatake ◽  
Mariana M. Belcheva ◽  
Kari T. Chambers ◽  
...  
Keyword(s):  
Kappa Opioids

Kappa opioids modulate the arterial baroreflex control of heart rate in conscious young sheep

2007 ◽  
Vol 85 (8) ◽  
pp. 811-817 ◽  
Author(s):  
Wei Qi ◽  
Francine G. Smith
Keyword(s):  
Heart Rate ◽  
Arterial Pressure ◽  
Direct Evidence ◽  
Opiate Receptors ◽  
Random Order ◽  
Arterial Baroreflex ◽  
Baroreflex Control ◽  
Physiological Conditions ◽  
Kappa Opioids ◽  
Before And After

The present study tested the hypothesis that κ-opioids modulate the arterial baroreflex control of heart rate in conscious young sheep. Various parameters governing the arterial baroreflex control of heart rate were assessed before and after activation of κ-opiate receptors (KOR) by i.v. administration of the specific KOR agonist U-50488H (experiment 1) or vehicle (experiment 2) to conscious, chronically instrumented lambs aged 42 ± 2 days (n = 6). The 2 experiments were administered in random order at minimum intervals of 48 h. Thirty min after U-50488H treatment, there was an increase in diastolic and mean arterial pressure and in heart rate, returning to control levels by 90 min. A significant increase in the arterial pressure at the midpoint of the baroreflex range and in the minimum heart rate as well as a significant decrease in the heart rate range over which the arterial baroreflex operates were also seen at 30 min after U-50488H, gradually returning to control levels over 120 min. Vehicle had no effect on any of the parameters governing the arterial baroreflex control of heart rate. These data provide the first direct evidence that under physiological conditions in young lambs, the arterial baroreflex control of heart rate is altered after administration of the specific KOR agonist U-50488H, revealing a previously unidentified role for this opioid receptor.

Sign in / Sign up

Export Citation Format

Share Document