Comparative analytical study of Ashuddha Karaveera and Shuddha Karaveera

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Apeksha D. Patil ◽  
Dhiraj B. Patil
Keyword(s):  
Stainless Steel ◽  
Analytical Study ◽  
Warm Water ◽  
Foreign Matter ◽  
Steel Vessel ◽  
Mild Heat ◽  
Stainless Steel Vessel ◽  
The Impact

Karaveera (Cerebra thevetia Linn.) is reported under Upavisha Dravya in classical ayurvedic pharmacopeias. It is observed that Shodhana (purification procedures) of the mool should be carried out before its internal administration. There are different Shodhana methods mentioned in Ayurveda. In this study Godugdha was used as media. The impact of Shodhana was evaluated by physico analytical study. It clearly proves physico analytical changes during Shodhana. Ashuddha Karaveera was taken on white clean cloth and they dumped in Pottali with Godugdha. Pottali was tied to middle of wooden rod dipped in Godugdha in stainless steel vessel and mild heat given to pottali in Dolayantra. Shuddha Karaveera was obtained and then washed with leuk warm water and dried. Ashuddha Karaveera contains toxin in it which was removed after Shodhana process. So that foreign matter, loss on drying was less in Shuddha Karaveera and due to Shodhan process with Godugdha total ash, acid insoluble ash was more than that of Ashuddha Karaveera.

scholarly journals Structural and functional brain-wide alterations in A350V Iqsec2 mutant mice displaying autistic-like behavior

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniela Lichtman ◽  
Eyal Bergmann ◽  
Alexandra Kavushansky ◽  
Nadav Cohen ◽  
Nina S. Levy ◽  
...  
Keyword(s):  
Social Behavior ◽  
Functional Connectivity ◽  
Mouse Model ◽  
Ampa Receptor ◽  
Social Preference ◽  
Autism Spectrum ◽  
Receptor Trafficking ◽  
Anterior Cingulate ◽  
The Impact ◽  
Ampa Receptor Trafficking

AbstractIQSEC2 is an X-linked gene that is associated with autism spectrum disorder (ASD), intellectual disability, and epilepsy. IQSEC2 is a postsynaptic density protein, localized on excitatory synapses as part of the NMDA receptor complex and is suggested to play a role in AMPA receptor trafficking and mediation of long-term depression. Here, we present brain-wide structural volumetric and functional connectivity characterization in a novel mouse model with a missense mutation in the IQ domain of IQSEC2 (A350V). Using high-resolution structural and functional MRI, we show that animals with the A350V mutation display increased whole-brain volume which was further found to be specific to the cerebral cortex and hippocampus. Moreover, using a data-driven approach we identify putative alterations in structure–function relations of the frontal, auditory, and visual networks in A350V mice. Examination of these alterations revealed an increase in functional connectivity between the anterior cingulate cortex and the dorsomedial striatum. We also show that corticostriatal functional connectivity is correlated with individual variability in social behavior only in A350V mice, as assessed using the three-chamber social preference test. Our results at the systems-level bridge the impact of previously reported changes in AMPA receptor trafficking to network-level disruption and impaired social behavior. Further, the A350V mouse model recapitulates similarly reported brain-wide changes in other ASD mouse models, with substantially different cellular-level pathologies that nonetheless result in similar brain-wide alterations, suggesting that novel therapeutic approaches in ASD that result in systems-level rescue will be relevant to IQSEC2 mutations.

Analytical Study of the Oblique Impact of a Rod with a Flat Using an Elasto-Plastic Contact Model

2015 ◽  
Vol 801 ◽  
pp. 25-32
Author(s):  
Ozdes Cermik ◽  
Hamid Ghaednia ◽  
Dan B. Marghitu
Keyword(s):  
Impact Velocity ◽  
Contact Force ◽  
Analytical Study ◽  
Initial Conditions ◽  
Permanent Deformation ◽  
Oblique Impact ◽  
Coefficient Of Restitution ◽  
Contact Model ◽  
Impact Angles ◽  
The Impact

In the current study a flattening contact model, combined with a permanent deformation expression, has been analyzed for the oblique impact case. The model has been simulated for different initial conditions using MATLAB. The initial impact velocity used for the simulations ranges from 0.5 to 3 m/s. The results are compared theoretically for four different impact angles including 20, 45, 70, and 90 degrees. The contact force, the linear and the angular motion, the permanent deformation, and the coefficient of restitution have been analyzed. It is assumed that sliding occurs throughout the impact.

scholarly journals Pakistan-United States Diplomatic Relations: Analytical Study

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Abdul Rahim , Dr. Adil Zaman Kasi
Keyword(s):  
United States ◽  
Analytical Study ◽  
Reciprocal Relationship ◽  
Impact Factors ◽  
Diplomatic Relations ◽  
Political Factors ◽  
The Social ◽  
Osama Bin Laden ◽  
Relationship Of ◽  
The Impact

This research paper discusses the reciprocal relationship of Pakistan and United States. Pakistan and United States are engaged in transactional relationship for gaining the credibility of through securing their national interest which bought distractive approaches in bilateral relationship. Historically, Pakistan-United States have been supporting each other against the terrorism as had strong diplomatic alignment in countering terrorism, extremism and fundamentalism. The distrust prevailed and occupied which dismantle the international move to dismantle the terror. The uncertainty of relationship causes a cataclysmic events which provides distrust as well as dismantle the international coalition for the peace establishment. This paper includes the diplomatic ties between Pakistan and United States specially post 9/11. The diplomatic successful alignment for the international peace brought effective orientation thereafter the impact factors of diverse misunderstanding which were mismanaged diplomatically as cases of Raymond Davis, Salala Check post, nuclear proliferation, Osama Bin Laden, Drone Attacks, and Memogate. Their diplopic move is essential to be revamped for the social, economic and political factors which sources the regional peace of South and Central Asia.  

scholarly journals Analytical Study on the Impact of GST on Retail Sector: With Reference to Dmart Financial Performance

2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Usha N.
Keyword(s):  
Financial Performance ◽  
Analytical Study ◽  
Retail Industry ◽  
Retail Sector ◽  
Trade Barriers ◽  
Model Law ◽  
The Impact

The imminent implementation of Goods & Services Tax (GST) is expected to result in greater transparency, an improved flow of credit, and reduced trade barriers from a tax perspective. The timely release and revision of the draft GST model law, GST rules, and documentation templates reflect the government’s commitment and keenness to implement the GST law in India in 2017. It is also widely agreed that GST will usher in a series of changes to how businesses will operate and the Retail Industry will be no exception. This thought piece highlights some of the key areas impacted and a number of changes that the industry will need to imbibe over the coming months to ensure that GST is effectively implemented.

scholarly journals A psychrometric model to assess the biological decay of the SARS-CoV-2 virus in aerosols

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11024
Author(s):  
Clive B. Beggs ◽  
Eldad J. Avital
Keyword(s):  
Air Temperature ◽  
Vapour Pressure ◽  
Half Life ◽  
Analytical Study ◽  
Decay Constant ◽  
Meteorological Data ◽  
Environmental Parameters ◽  
Published Data ◽  
Reasonable Accuracy ◽  
The Impact

There is increasing evidence that the 2020 COVID-19 pandemic has been influenced by variations in air temperature and humidity. However, the impact that these environmental parameters have on survival of the SARS-CoV-2 virus has not been fully characterised. Therefore, an analytical study was undertaken using published data to develop a psychrometric model to assess the biological decay rate of the virus in aerosols. This revealed that it is possible to describe with reasonable accuracy (R2 = 0.718, p < 0.001) the biological decay constant for the SARS-CoV-2 virus using a regression model with enthalpy, vapour pressure and specific volume as predictors. Applying this to historical meteorological data from London, Paris and Milan over the pandemic period, produced results which indicate that the average half-life of the virus in aerosols outdoors was in the region 13–22 times longer in March 2020, when the outbreak was accelerating, than it was in August 2020 when epidemic in Europe was at its nadir. However, indoors, this variation is likely to be much less. As such, this suggests that changes in virus survivability due the variations in the psychrometric qualities of the air might influence the transmission of SARS-CoV-2.

Sign in / Sign up

Export Citation Format

Share Document