Inhibition Effect of a Hot Water Extracts from Sargassum Fulvellum AgainstGluten-induced Inflammation and Oxidative Damage in Human Keratinocytes

2019 ◽  
Vol 24 (2) ◽  
pp. 90-98
Author(s):  
Eun-Ji Shin ◽  
Eui Jeong Han ◽  
Min Ju Kim ◽  
Jaekyu Jung ◽  
Junyoung Park ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Human Keratinocytes ◽  
Hot Water ◽  
Inhibition Effect ◽  
Water Extracts ◽  
Sargassum Fulvellum

Inhibitory Effect of hot Water Extracts from Ecklonia Cava on Oxidative Damage and Inflammation Caused by Gluten in Human Keratinocytes

2019 ◽  
Vol 24 (4) ◽  
pp. 246-254
Author(s):  
Eui Jeong Han ◽  
Min ju Kim ◽  
Eun-Ji Shin ◽  
Jaekyu Jung ◽  
Junyoung Park ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Human Keratinocytes ◽  
Inhibitory Effect ◽  
Hot Water ◽  
Ecklonia Cava ◽  
Water Extracts

scholarly journals Protective Effect of Chrysanthemum morifolium cv. Fubaiju Hot-Water Extracts Against ARPE-19 Cell Oxidative Damage by Activating PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway

2021 ◽  
Vol 8 ◽  
Author(s):  
Yiming Hao ◽  
Yanfang Li ◽  
Jie Liu ◽  
Ziyuan Wang ◽  
Boyan Gao ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Protective Effect ◽  
Signaling Pathway ◽  
Chrysanthemum Morifolium ◽  
Hot Water ◽  
Expression Level ◽  
Heme Oxygenase 1 ◽  
Related Factor ◽  
Dependent Manner ◽  
Water Extracts

Chrysanthemum morifolium cv. Fubaiju is a kind of widely consumed herb tea with multiple health benefits. The present study was aimed to evaluate the protective capacity of C. morifolium cv. Fubaiju hot-water extracts (CMs) against ARPE-19 cell oxidative damage. The results showed that pretreatment with 100 μg/mL CM could significantly reduce cell oxidative damage and apoptosis. Proapoptotic protein expression such as Bax, cleaved caspase-3, and cleaved poly(ADP-ribose) polymerase (PARP) was significantly decreased after CM addition, while the expression level of antioxidant enzymes including catalase, glutamate-cysteine ligase catalytic subunit (GCLc), superoxide dismutase 2 (SOD2), and NAD(P)H:quinone oxidoreductase 1 (NQO-1) was significantly promoted. Meanwhile, CM treatment upregulated Akt phosphorylation, nuclear factor erythroid 2-related factor 2 (Nrf2) nuclear translocation, and the expression level of antioxidant gene heme oxygenase-1 (HO-1) in a dose-dependent manner under oxidative stress. Knockdown of Nrf2 by targeted small interfering RNA (siRNA) alleviated CM-mediated HO-1 transcription and almost abolished CM-mediated protection against hydrogen peroxide (H2O2)-induced cell damage. Correspondingly, the protective effect of CM was dramatically blocked after interference with phosphatidylinositol 3-kinase (PI3K)/Akt inhibitor LY294002, indicating that the protective effect of CM on cell oxidative damage was attributed to PI3K/Akt-mediated Nrf2/HO-1 signaling pathway.

Evaluation on the Muscular Strength Activity of Medicinal Herb Hot-Water Extracts

2007 ◽  
Vol 36 (6) ◽  
pp. 678-682 ◽  
Author(s):  
Chang-Ho Lee ◽  
Young-Eon Kim ◽  
In-Ho Kim ◽  
Dae-Seok Han ◽  
Ki-Seung Seong ◽  
...  
Keyword(s):  
Muscular Strength ◽  
Medicinal Herb ◽  
Hot Water ◽  
Water Extracts

Quality Characteristics of Pound Cake Made with Gamma Irradiated Hot Water Extracts of Undaria pinnatifida Sporophyll

2011 ◽  
Vol 40 (10) ◽  
pp. 1460-1468
Author(s):  
Da-Mi Kim ◽  
Kyoung-Hee Kim ◽  
Young-Sik Yun ◽  
Jae-Hun Kim ◽  
Ju-Woon Lee ◽  
...  
Keyword(s):  
Undaria Pinnatifida ◽  
Quality Characteristics ◽  
Hot Water ◽  
Water Extracts ◽  
Gamma Irradiated

scholarly journals Effect of Water and Ethanol Extracts from Hericium erinaceus Solid-State Fermented Wheat Product on the Protection and Repair of Brain Cells in Zebrafish Embryos

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3297
Author(s):  
Shun-Kuo Sun ◽  
Chun-Yi Ho ◽  
Wei-Yang Yen ◽  
Su-Der Chen
Keyword(s):  
Solid State ◽  
Brain Cell ◽  
Hot Water ◽  
Raw Material ◽  
Brain Cells ◽  
Zebrafish Embryos ◽  
Hericium Erinaceus ◽  
Water Extracts ◽  
The Brain ◽  
Wheat Product

Extracts from Hericium erinaceus can cause neural cells to produce nerve growth factor (NGF) and protect against neuron death. The objective of this study was to evaluate the effects of ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product on the brain cells of zebrafish embryos in both pre-dosing protection mode and post-dosing repair mode. The results showed that 1% ethanol could effectively promote zebrafish embryo brain cell death. Both 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product protected brain cells and significantly reduced the death of brain cells caused by 1% ethanol treatment in zebrafish. Moreover, the zebrafish embryos were immersed in 1% ethanol for 4 h to cause brain cell damage and were then transferred and soaked in the 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product to restore the brain cells damaged by the 1% ethanol. However, the 200 ppm extracts from the unfermented wheat medium had no protective and repairing effects. Moreover, 200 ppm of ethanol and water extracts from H. erinaceus fruiting body had less significant protective and restorative effects on the brain cells of zebrafish embryos. Both the ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product could protect and repair the brain cells of zebrafish embryos damaged by 1% ethanol. Therefore, it has great potential as a raw material for neuroprotective health product.

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