scholarly journals Effect of heavy metal and some trace element levels on radiotherapy taken breast cancer patients

2016 ◽  
Vol 3 (3) ◽  
pp. 116
Author(s):  
Halit Demir ◽  
Canan Demir
Nutrients ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 37 ◽  
Author(s):  
Rihwa Choi ◽  
Min-Ji Kim ◽  
Insuk Sohn ◽  
Serim Kim ◽  
Isaac Kim ◽  
...  

The relationships between serum levels of trace elements and breast cancer remain relatively unknown. In this study, we investigate serum levels of seven trace elements in Korean breast cancer patients compared to controls without breast cancer. Serum trace element levels were determined using inductively coupled plasma mass spectrometry in Korean breast cancer patients before initiation of breast cancer treatment. Korean females without breast cancer served as a control group. Trace element levels were measured in the discovery cohort (n = 287) and were validated in an independent cohort (n = 142). We further investigated possible associations between trace element levels and the presence of lymph node metastasis, distant metastasis, or triple-negative breast cancer among breast cancer patients in subgroup analyses. Serum manganese and molybdenum levels were significantly higher (p < 0.05) in breast cancer patients than in controls. Serum copper levels were significantly higher in breast cancer patients with distant metastasis, while selenium levels were significantly lower. Other trace elements were neither significantly different between breast cancer patients and controls nor between subgroups of breast cancer patients. Our study provides insights about the potential roles and impacts of trace elements through an assessment of the associations between trace elements and breast cancer.


2011 ◽  
Vol 17 (6) ◽  
pp. 575-583 ◽  
Author(s):  
Jia-Fu Feng ◽  
Ling Lu ◽  
Ping Zeng ◽  
Yun-Hong Yang ◽  
Jun Luo ◽  
...  

The Breast ◽  
2018 ◽  
Vol 42 ◽  
pp. 142-149 ◽  
Author(s):  
Noemí Cabré ◽  
Fedra Luciano-Mateo ◽  
Meritxell Arenas ◽  
Martí Nadal ◽  
Gerard Baiges-Gaya ◽  
...  

2014 ◽  
Vol 24 (01n02) ◽  
pp. 49-58 ◽  
Author(s):  
Z. Kabiri ◽  
O. Kakuee ◽  
V. Fathollahi ◽  
B. Stout

Development of a number of diseases like cardiovascular diseases and cancer has been related with abnormalities of certain trace elements in some tissues. The purpose of this study was to investigate the levels of trace elements in breast cancer patients in comparison with healthy controls. Particle induced X-ray emission (PIXE) technique was employed to measure the hair trace element concentrations in 30 cancer patients and 30 healthy controls. A 2.2 MeV proton beam was employed to excite the biological samples. The concentrations of Fe and Cu ([Formula: see text]) in the hair of cancer patients were found to be higher compared to those of healthy controls, while the concentration of Zn ([Formula: see text]) was found to be lower. No significant difference was observed for sulfur concentration between the two groups. Also, no meaningful difference was observed in the concentrations of K, Ca, Ti as well as ratios of Cu/Zn and Cu/Fe in the hair of the two groups ([Formula: see text]). These abnormalities could potentially be used as a means of breast cancer screening in women.


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