scholarly journals STRUCTURAL -FUNCTIONAL CHANGES IN THE BRAIN, LUNGS AND HEART OF RATS AT POISONING WITH CARBON GAS IN THE BACKGROUND OF ALCOHOLIC INTOXICATION

2021 ◽  
pp. 95-95
Author(s):  
D.A. Enikeev ◽  
A.E. Ryakhovskiy ◽  
E.N. Khisamov ◽  
D.S. Kuklin
Keyword(s):  
Functional Changes ◽  
Alcoholic Intoxication ◽  
The Brain

scholarly journals Contribution of Neuroinflammation to the Pathogenesis of Cancer Cachexia

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Alessio Molfino ◽  
Gianfranco Gioia ◽  
Filippo Rossi Fanelli ◽  
Alessandro Laviano
Keyword(s):  
Adipose Tissue ◽  
Food Intake ◽  
Proinflammatory Cytokines ◽  
Adaptive Response ◽  
Energy Homeostasis ◽  
Cancer Cachexia ◽  
Behavioral Changes ◽  
Brain Areas ◽  
Functional Changes ◽  
The Brain

Inflammation characterizes the course of acute and chronic diseases and is largely responsible for the metabolic and behavioral changes occurring during the clinical journey of patients. Robust data indicate that, during cancer, functional modifications within brain areas regulating energy homeostasis contribute to the onset of anorexia, reduced food intake, and increased catabolism of muscle mass and adipose tissue. In particular, functional changes are associated with increased hypothalamic concentration of proinflammatory cytokines, which suggests that neuroinflammation may represent the adaptive response of the brain to peripheral challenges, including tumor growth. Within this conceptual framework, the vagus nerve appears to be involved in conveying alert signals to the hypothalamus, whereas hypothalamic serotonin appears to contribute to triggering catabolic signals.

Economics & Practical Applications for Applied Trauma Theory

2013 ◽  
Vol 2 (2) ◽  
pp. 41-55 ◽  
Author(s):  
David S. Bathory
Keyword(s):  
World Wide ◽  
Rural Tourism ◽  
Clinical Population ◽  
Intergenerational Effects ◽  
Mass Trauma ◽  
Practical Applications ◽  
Functional Changes ◽  
The World ◽  
South Eastern Europe ◽  
The Brain

The effects of global warming are becoming apparent throughout the world. Europe has begun to experience more severe winters and increased rain (Steffen, 2011). Massive flooding in South Eastern Europe has devastated communities and repeatedly strains the economy of these regions resulting in mass trauma to the residents of multiple countries. Intergenerational effects of trauma (Kaitz, Levy, Ebstein, Faraone, & Mankuta, 2009) have been noted to be an increasing world-wide concern. These traumatic effects are not only psychologically based but result in structural and functional changes within the brain and body (van der Kolk, Roth, Pelcovitz, Sunday, & Spinazzola, 2005; Bathory, 2011; Bathory, 2012a; Bathory, 2012b). This paper explores the application of sustainable energy and rural tourism to assist mass victims of natural disaster flooding. The author provides the cultural precedents for marketing, as well as the psychoneurobiological rationale and application for an intervention to a large non-clinical population.

scholarly journals Investigating functional changes in the brain to intermittently induced auditory illusions and its relevance to chronic tinnitus

2020 ◽  
Vol 41 (7) ◽  
pp. 1819-1832 ◽  
Author(s):  
Anusha Mohan ◽  
Neil Bhamoo ◽  
Juan S. Riquelme ◽  
Samantha Long ◽  
Arnaud Norena ◽  
...  
Keyword(s):  
Chronic Tinnitus ◽  
Functional Changes ◽  
The Brain

scholarly journals A Multimodal Meta-Analysis of Structural and Functional Changes in the Brain of Tinnitus

2020 ◽  
Vol 14 ◽  
Author(s):  
Shirui Cheng ◽  
Guixing Xu ◽  
Jun Zhou ◽  
Yuzhu Qu ◽  
Zhengjie Li ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Functional Changes ◽  
The Brain

Neurophysiological evaluation of canine congenital hydrocephalus in three dogs

2020 ◽  
Vol 8 (1) ◽  
pp. e000949
Author(s):  
Mary Gutiérrez ◽  
Gimena Feijóo ◽  
Luis J Delucchi
Keyword(s):  
Auditory Evoked Potentials ◽  
Epileptiform Activity ◽  
Clinical Signs ◽  
Congenital Hydrocephalus ◽  
Bioelectrical Activity ◽  
Functional Changes ◽  
Sharp Waves ◽  
Clinical Responses ◽  
The Brain ◽  
Cerebrospinal Fluid Volume

Congenital hydrocephalus is a neurological disorder frequently observed in dogs. It is characterised by an increase of cerebrospinal fluid volume in the ventricular system that can cause atrophy of brain tissue. It can be provoked by diverse causes, as it can be idiopathic or secondary to nervous system abnormalities. Diagnosis is based on clinical signs and imaging studies, but neurophysiological techniques can provide valuable information. This report describes functional changes in the brain and brainstem evaluated by electroencephalogram and auditory evoked potentials. In the three cases, the authors found alterations in background rhythm, slow waves, epileptiform activity, hypsarrhythmic tracing and positive sharp waves. These techniques allow detecting alterations in the brain bioelectrical activity that do not trigger clear clinical responses.

DETECTION OF Ca2+-DEPENDENT NEURONAL ACTIVITY SIMULTANEOUSLY WITH DYNAMIC CHANGES IN CEREBRAL BLOOD VOLUME AND TISSUE OXYGENATION FROM THE LIVE RAT BRAIN

2009 ◽  
Vol 02 (02) ◽  
pp. 189-200 ◽  
Author(s):  
CONGWU DU ◽  
ZHONGCHI LUO ◽  
MEI YU ◽  
HELENE BENVENISTE ◽  
MELISSA TULLY ◽  
...  
Keyword(s):  
Rat Brain ◽  
Blood Volume ◽  
Neuronal Activity ◽  
Cerebral Blood Volume ◽  
Tissue Oxygenation ◽  
Simultaneous Detection ◽  
Fluorescence Emission ◽  
High Temporal Resolution ◽  
Functional Changes ◽  
The Brain

We present a catheter-based optical diffusion and fluorescence (ODF) probe to study the functional changes of the brain in vivo. This ODF probe enables the simultaneous detection of the multi-wavelength absorbance and fluorescence emission from the living rat brain. Our previous studies, including a transient stroke experiment of the rat brain as well as the brain response to cocaine, have established the feasibility of simultaneously determining changes in cerebral blood volume (CBV), tissue oxygenation ( S t O 2) and intracellular calcium ([ Ca 2+]i, using the fluorescence indicator Rhod2). Here, we present our preliminary results of somatosensory response to electrical forepaw stimulation obtained from the rat cortical brain by using the ODF probe, which indicate that the probe could track brain activation by directly detecting [ Ca 2+]i along with separately distinguishing CBV and S t O 2 in real time. The changes of CBV, S t O 2 and [ Ca 2+]i are comparable with the blood-oxygen-level-dependent (BOLD) response to the stimulation obtained using functional magnetic resonance imaging (fMRI). However, the high temporal resolution of the optical methodology is advanced, thus providing a new modality for brain functional studies to understand the hemodynamic changes that underlie the neuronal activity.

scholarly journals Brain Plasticity and Behavior

2003 ◽  
Vol 12 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Bryan Kolb ◽  
Robbin Gibb ◽  
Terry E. Robinson
Keyword(s):  
Brain Plasticity ◽  
Recovery Of Function ◽  
Psychological Disorders ◽  
Abnormal Behavior ◽  
Brain Organization ◽  
Functional Changes ◽  
Brain Circuitry ◽  
And Function ◽  
And Behavior ◽  
The Brain

Although the brain was once seen as a rather static organ, it is now clear that the organization of brain circuitry is constantly changing as a function of experience. These changes are referred to as brain plasticity, and they are associated with functional changes that include phenomena such as memory, addiction, and recovery of function. Recent research has shown that brain plasticity and behavior can be influenced by a myriad of factors, including both pre- and postnatal experience, drugs, hormones, maturation, aging, diet, disease, and stress. Understanding how these factors influence brain organization and function is important not only for understanding both normal and abnormal behavior, but also for designing treatments for behavioral and psychological disorders ranging from addiction to stroke.

scholarly journals Abundance of the α-subunits of Gi1, Gi2 and Go in synaptosomal membranes from several regions of the rat brain is increased in hypothyroidism

1991 ◽  
Vol 275 (1) ◽  
pp. 183-186 ◽  
Author(s):  
M Orford ◽  
D Mazurkiewicz ◽  
G Milligan ◽  
D Saggerson
Keyword(s):  
G Protein ◽  
Signalling Pathways ◽  
Synaptosomal Membranes ◽  
Protein Subunits ◽  
Functional Changes ◽  
Alpha Subunits ◽  
The Central Nervous System ◽  
Quantitative Immunoblotting ◽  
The Brain ◽  
Α Subunits

1. Rats (4 weeks old) were made hypothyroid by treatment with propylthiouracil together with a low-iodine diet for a further period of 4 weeks. Synaptosomal membranes were obtained from six anatomical regions of the brain. 2. The abundances in these membranes of the G-protein alpha-subunits Gi1 alpha, Gi2 alpha and Go alpha were measured by quantitative immunoblotting. 3. Hypothyroidism significantly increased the abundances of all three G-protein subunits in membranes from the cerebral cortex and the striatum. In the medulla oblongata and the hippocampus the abundances of Gi2 alpha and Go alpha were increased significantly. By contrast, in the cerebellum only Go alpha was increased, and in the hypothalamus only Gi2 alpha was increased. 4. It is suggested that this up-regulation of G-protein abundances may modify signalling pathways and may contribute to the functional changes that are observed in the central nervous system in hypothyroidism.

Sign in / Sign up

Export Citation Format

Share Document