scholarly journals ALTERATIONS OF EXPRESSION OF VASCULAR ADHESION MOLECULES IN URINARY DISEASE

Author(s):  
A.G. Berezhnoy ◽  
S.S. Dunaevskaya
Immunobiology ◽  
1997 ◽  
Vol 197 (5) ◽  
pp. 505-512 ◽  
Author(s):  
Bernd Jilma ◽  
Hans-Georg Eichler ◽  
Petra Stohlawetz ◽  
Eva Dirnberger ◽  
Stylianos Kapiotis ◽  
...  

2014 ◽  
Vol 18 (4) ◽  
pp. 869-874 ◽  
Author(s):  
Guoda Pilkauskaite ◽  
Skaidrius Miliauskas ◽  
Astra Vitkauskiene ◽  
Raimundas Sakalauskas

AGE ◽  
2014 ◽  
Vol 36 (5) ◽  
Author(s):  
Berta Anuncibay-Soto ◽  
Diego Pérez-Rodríguez ◽  
Irene L Llorente ◽  
Marta Regueiro-Purriños ◽  
José Manuel Gonzalo-Orden ◽  
...  

Hepatology ◽  
1992 ◽  
Vol 15 (2) ◽  
pp. 269-275 ◽  
Author(s):  
Riccardo Volpes ◽  
Joost J. van den Oord ◽  
Valeer J. Desmet

1998 ◽  
Vol 89 (4) ◽  
pp. 559-567 ◽  
Author(s):  
Richard S. Polin ◽  
Murad Bavbek ◽  
Mark E. Shaffrey ◽  
Kevin Billups ◽  
Christopher A. Bogaev ◽  
...  

Object. The goal of this study was to explore whether the levels of soluble adhesion molecules were elevated in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH). This association was suggested by the known inflammatory response in vasospasm and the role of vascular adhesion molecules in regulating leukocytic adhesion to, and migration across, vascular endothelium. Methods. A prospective analysis was performed on CSF samples obtained in 17 patients who had suffered a recent aneurysmal SAH and in 16 control patients by using quantitative enzyme-linked immunosorbent assays for E-selectin, intercellular adhesion molecule—1 (ICAM—1), vascular adhesion molecule—1 (VCAM-1), and L-selectin. Levels of soluble forms of E-selectin (p = 0.0013), ICAM-1 (p = 0.0001), and VCAM-1 (p = 0.048) were found to be elevated in the CSF of patients after SAH compared with levels in the CSF of normal controls, patients with unruptured aneurysms, and patients tested months after SAH occurred. In addition, individual patients tested at the time of their initial ictus demonstrated a fall in adhesion molecule levels over time. Levels of E-selectin (p = 0.044) were highest in patients who later developed moderate or severe vasospasm. Conclusions. Adhesion molecules are known to be involved in white cell adherence to the endothelium and subsequent diapedesis and migration in which a role in initiation of tissue damage is postulated. The authors have demonstrated the elevation of three adhesion molecules, with severely elevated levels of E-selectin seen in patients who later develop vasospasm. A correlation with a role of vascular adhesion molecules in the pathogenesis of cerebral vasospasm is suggested.


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