scholarly journals RISK FACTORS AND FEATURES OF GENE POLYMORPHISMS OF THE MATERNAL HEMOSTASIS SYSTEM FOR PREDICTING THE DEVELOPMENT OF HEMORRHAGIC DISORDERS IN PREMATURE NEWBORNS

2020 ◽  
pp. 76-76
Author(s):  
A.V. Budalova ◽  
N.V. Kharlamova ◽  
I.N. Fetisova ◽  
E.A. Rokotyanskaya ◽  
A.O. Nazarova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gene Polymorphisms ◽  
Premature Newborns ◽  
Hemostasis System ◽  
Hemorrhagic Disorders

Thrombophilic risk factors are laterally associated with Apolipoprotein E gene polymorphisms in deep vein thrombosis patients: An Indian study

2018 ◽  
Vol 34 (5) ◽  
pp. 324-335
Author(s):  
Pulkit Rastogi ◽  
Narender Kumar ◽  
Jasmina Ahluwalia ◽  
Reena Das ◽  
Neelam Varma ◽  
...  
Keyword(s):  
Risk Factors ◽  
Deep Vein Thrombosis ◽  
Gene Polymorphisms ◽  
Apoe Gene ◽  
Therapeutic Implications ◽  
Vein Thrombosis ◽  
Apolipoprotein E Gene ◽  
Polymerase Chain ◽  
Apoe Genotypes ◽  
Deep Vein

Introduction Deep vein thrombosis is a multifactorial disease with many acquired and genetic risk factors. Polymorphism in the APOE gene is an upcoming potential pathogenic factor whose role is unclear in deep vein thrombosis. Methods An equal number of deep vein thrombosis cases and controls (N = 100, each) were investigated for APOE gene polymorphisms along with known acquired and hereditable thrombophilic risk factors. APOE genotyping was done by polymerase chain reaction. Results The ε3/ε4 and ε2/ε3 APOE genotypes were commoner in deep vein thrombosis cases than controls but not statistically significant ( ε3/ε4 → 18% versus 11%, OR = 1.776, CI = 0.792–3.984, p = 0.16; ε2/ε3 →10% versus 9%, OR = 1.123, CI = 0.436–2.895, p = 0.809). However, the following risk factors were found to be laterally associated with APOE genotypes in cases of deep vein thrombosis: pregnancy with ε2/ε3 genotype positivity (N = 29; p = 0.019), recurrent pregnancy loss with ε3/ε3 genotype (N = 29; p = 0.016), normal antithrombin levels with ε3/ε3 genotype (N = 62; p = 0.03) and non-O blood group with ε3/ε4 genotype (N = 100; p = 0.023). Conclusion APOE genotypes have shown only a modest association with deep vein thrombosis and were not statistically significant. A lateral association of these genotypes with thrombophilic risk factors was observed which may be investigated further for the possible pathogenetic mechanisms and their therapeutic implications.

scholarly journals Multiple Pregnancy and Oligoamnios as Risk Factors for Refractory Hypoxemia in Very Premature Newborns

1999 ◽  
Vol 45 (4, Part 2 of 2) ◽  
pp. 254A-254A
Author(s):  
Jean C Roze ◽  
Caroline Hurtin ◽  
Christelle Gras ◽  
Cecile Bosher ◽  
Thierry Debillon
Keyword(s):  
Risk Factors ◽  
Multiple Pregnancy ◽  
Premature Newborns ◽  
Refractory Hypoxemia

Association of cytokine gene polymorphisms and risk factors with otitis media proneness in children

2016 ◽  
Vol 175 (6) ◽  
pp. 809-815 ◽  
Author(s):  
Olivera Miljanović ◽  
Bojana Cikota-Aleksić ◽  
Dragan Likić ◽  
Danilo Vojvodić ◽  
Ognjen Jovićević ◽  
...  
Keyword(s):  
Risk Factors ◽  
Otitis Media ◽  
Gene Polymorphisms ◽  
Cytokine Gene ◽  
Cytokine Gene Polymorphisms

PARK2 and PARK7 Gene Polymorphisms as Risk Factors Associated with Serum Element Concentrations and Clinical Symptoms of Parkinson’s Disease

2019 ◽  
Vol 40 (3) ◽  
pp. 357-367
Author(s):  
Jaya Sanyal ◽  
Athira Anirudhan ◽  
Tapas Kumar Banerjee ◽  
Gautam Guha ◽  
Ramakrishnan Veerabathiran ◽  
...  
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Gene Polymorphisms ◽  
Clinical Symptoms ◽  
Factors Associated ◽  
Element Concentrations

IL-18 and IL-1β Gene Polymorphisms: The Plausible Risk Factors for Chronic Hepatitis B

2019 ◽  
Vol 32 (5) ◽  
pp. 208-213
Author(s):  
Sahar Amirpour-Rostami ◽  
Mohammad Kazemi Arababadi
Keyword(s):  
Risk Factors ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Gene Polymorphisms

scholarly journals P1.02-007 TP53 and DNA-Repair Gene Polymorphisms as Risk Factors for the Development of Advanced Lung Adenocarcinoma in Serbia

2017 ◽  
Vol 12 (11) ◽  
pp. S1927
Author(s):  
J. Spasic ◽  
A. Krivokuca ◽  
B. Zaric ◽  
D. Radosavljevic ◽  
B. Perin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dna Repair ◽  
Lung Adenocarcinoma ◽  
Gene Polymorphisms ◽  
Repair Gene ◽  
Dna Repair Gene
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