scholarly journals THE ROLE OF CHEMICAL AGENTS IN THE GENESIS OF ACUTE LEUKEMIA IN CHILDREN

2020 ◽  
pp. 93-93
Author(s):  
A.Y. Dulatov ◽  
A.A. Amankulova ◽  
E.K. Makimbetov
Keyword(s):  
Acute Leukemia ◽  
Chemical Agents ◽  
Leukemia In Children

Evidence Against the Role of Hepatitis C Virus in Severe Liver Damage Occurring Early in the Course of Acute Leukemia in Children

1994 ◽  
Vol 13 (1-2) ◽  
pp. 119-122 ◽  
Author(s):  
Anna Locasciulli ◽  
Patrizia Pontisso ◽  
Daniela Cavalletto ◽  
Donatella Fraschini ◽  
Cornelio Uderzo ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Acute Leukemia ◽  
Liver Damage ◽  
Severe Liver ◽  
Severe Liver Damage ◽  
Leukemia In Children

GROUP DISCUSSIONS WITH THE PARENTS OF LEUKEMIC CHILDREN

PEDIATRICS ◽  
1973 ◽  
Vol 52 (6) ◽  
pp. 831-840
Author(s):  
Warren A. Heffron ◽  
Karen Bommelaere ◽  
Ruth Masters
Keyword(s):  
Acute Leukemia ◽  
Information Dissemination ◽  
Death And Dying ◽  
Group Discussions ◽  
Shared Experiences ◽  
Valuable Adjunct ◽  
The Family ◽  
Leukemia Treatment ◽  
Leukemia In Children

Group meetings are being used in increasing numbers in many divergent areas of patient care. A group for parents of children with acute leukemia was established in conjunction with a leukemia treatment program. The group met weekly and served as a means of problem identification and solution. Areas discussed were problems concerning patients, parents, siblings, friends, and the medical team. It also served as a forum for information dissemination. It was found that in the management of leukemia in children, the group served as a strengthening of the family during crisis episodes. Discussions of death and dying were difficult, and the death of another parent's child was traumatic to all. However, the benefits of shared experiences outweighed these difficulties. Parents developed a better understanding of leukemia and its treatment and felt that their ability to cope with associated problems was enhanced. Both the families and staff felt the group was a valuable adjunct to the management of acute leukemia in children. As far as the authors are able to determine this use of a group has not been reported in this form in leukemia management. The evaluation of the success of this group is largely subjective. It is hoped that others will employ the use of such a group and in larger numbers perhaps some degree of objectivity might be able to be developed to adequately evaluate the role of groups in leukemia clinics as well as other areas of medical practice.

The Role of Apoptosis in the Course of Acute Leukemia in Children

2001 ◽  
pp. 120-123
Author(s):  
A. Chybicka ◽  
D. Turkiewicz ◽  
B. Rybka ◽  
R. Ryczan ◽  
J. Boguslawska-Jaworska
Keyword(s):  
Acute Leukemia ◽  
Leukemia In Children

scholarly journals The role of CALM–AF10 gene fusion in acute leukemia

Leukemia ◽  
2007 ◽  
Vol 22 (4) ◽  
pp. 678-685 ◽  
Author(s):  
D Caudell ◽  
P D Aplan
Keyword(s):  
Acute Leukemia ◽  
Gene Fusion

VINCRISTINE IN THE TREATMENT OF ACUTE LEUKEMIA IN CHILDREN

PEDIATRICS ◽  
1966 ◽  
Vol 38 (1) ◽  
pp. 82-91
Author(s):  
Ruth M. Heyn ◽  
E. C. Beatty ◽  
D. Hammond ◽  
J. Louis ◽  
M. Pierce ◽  
...  
Keyword(s):  
Complete Remission ◽  
Maintenance Therapy ◽  
Acute Leukemia ◽  
Median Duration ◽  
Drug Toxicity ◽  
Gastrointestinal Symptoms ◽  
Duration Of Disease ◽  
Common Problems ◽  
Leukemia In Children ◽  
Onset Of Remission

Vcr induced complete marrow remission in 43% of children with all types of acute leukemia who were refractory to other antileukemic therapy. The median duration of disease before Vcr treatment was 13.5 months. The marrow response in those patients achieving an A marrow was rapid with a marked clearing of the blasts by 14 days and a complete remission by 28 days. The median duration of complete remission with and without maintenance therapy was 63.5 and 59 days, respectively. Drug toxicity occurred in about half the patients, limiting the total dose of drug that could be given. Leukopenia, alopecia, gastrointestinal symptoms, and neurotoxicity were the most common problems seen. These were reversible on withdrawal of the drug. Remissions were not improved by increasing the dose of Vcr to 0.1 mg/kg for two or more doses after 4 doses of 0.075 mg/kg. The reduction in dose necessitated by drug toxicity was not detrimental to a good response since the children attaining complete remissions experienced the greatest number of alterations in dose prior to the onset of remission.

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