scholarly journals LONG-TERM IN-STENT RESTENOSIS DEVELOPMENT IN CORONARY ARTERIES AFTER PERCUTANEOUS CORONARY INTERVENTIONS WITH BARE METAL AND DRUG-ELUTING STENTS IMPLANTATION DEPENDING ON CLINICAL DATA AND RISK FACTORS

2017 ◽  
Author(s):  
V.P. Mazaev ◽  
A.A. Komkov ◽  
S.V. Ryazanova
Keyword(s):  
Risk Factors ◽  
Coronary Arteries ◽  
Drug Eluting Stents ◽  
Percutaneous Coronary Interventions ◽  
Bare Metal ◽  
Stent Restenosis ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
In Stent Restenosis

Treatment of In-stent Restenosis – Past, Present and Future

2009 ◽  
Vol 5 (2) ◽  
pp. 74 ◽  
Author(s):  
Fernando Alfonso ◽  
Keyword(s):  
Clinical Problem ◽  
Historical Background ◽  
Drug Eluting Stents ◽  
Bare Metal ◽  
Future Perspectives ◽  
Technical Challenge ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
In Stent Restenosis

In-stent restenosis (ISR) remains a significant clinical problem. The penetration of drug-eluting stents (DES) is quite variable and patients with DES may also suffer from ISR. Treatment of ISR remains a technical challenge and the long-term clinical outcome of these patients may be complicated by recurrences. Different strategies have been used for the treatment of patients with bare-metal ISR. Currently, DES constitute the intervention of choice in this setting. However, the best intervention for patients suffering from ISR after DES implantation remains to be elucidated. This report summarises our clinical and research efforts in this adverse anatomical scenario over the last decade. We will address the treatment of patients with ISR, revisiting the historical background, emphasising the currently available alternatives and disclosing future perspectives.

scholarly journals Drug eluting stents for the treatment of bare metal in-stent restenosis: long-term outcomes in real world practice

2011 ◽  
Vol 6 (6) ◽  
pp. 748-753 ◽  
Author(s):  
Clare Appleby ◽  
Raj Khattar ◽  
Kenneth Morgan ◽  
Bernard Clarke ◽  
Nicholas Curzen ◽  
...  
Keyword(s):  
Real World ◽  
Drug Eluting Stents ◽  
Bare Metal ◽  
Long Term Outcomes ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
In Stent Restenosis

scholarly journals A Case of Very Early Stent Restenosis Following DES Implantation

2019 ◽  
Vol 04 (04) ◽  
pp. 200-203 ◽  
Author(s):  
Shravan Kumar Ch ◽  
Naveen Kumar M. ◽  
Sudhakar Kanumuri
Keyword(s):  
Bare Metal Stents ◽  
Coronary Intervention ◽  
Drug Eluting Stents ◽  
Metal Stents ◽  
Bare Metal ◽  
Stent Restenosis ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
In Stent Restenosis ◽  
Stent Stenosis

AbstractIntracoronary in-stent restenosis (ISR) is more common with bare metal stents. With the introduction of drug-eluting stents (DESs), the incidence of ISR has markedly decreased. Here, we report a case of unusual very early stent restenosis in a patient who presented with unstable angina 15 days after percutaneous coronary intervention with sirolimus-eluting DES. Optical coherence tomography (OCT) was done to know the pathophysiology of the very early stent stenosis and the possibilities of the rare findings of this OCT are discussed.

scholarly journals Clinical Outcomes of Drug-Eluting versus Bare-Metal In-Stent Restenosis after the Treatment of Drug-Eluting Stent or Drug-Eluting Balloon: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Yi-Xing Yang ◽  
Yin Liu ◽  
Chang-Ping Li ◽  
Peng-Ju Lu ◽  
Jiao Wang ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Bare Metal ◽  
Stent Restenosis ◽  
Positive Prevention ◽  
Drug Eluting ◽  
Drug Eluting Balloon ◽  
In Stent Restenosis

Background. Although drug-eluting stents (DES) have reduced the rates of in-stent restenosis (ISR) compared with bare-metal stents (BMS), DES related ISR (DES-ISR) still occurs and outcomes of DES-ISR remain unclear. The objective of this meta-analysis was to investigate the long-term clinical outcomes of patients with DES-ISR compared with patients with BMS related ISR (BMS-ISR) after the treatment of DES or drug-eluting balloon (DEB). Methods and results. We searched the literature in the main electronic databases including PUBMED, EMBASE, Cochrane Library, and Web of Science. The primary endpoints were target lesion revascularization (TLR) and target vessel revascularization (TVR). The secondary endpoints included all cause death (ACD), cardiac death (CD), myocardial infarction (MI), stent thrombosis or re-in-stent restenosis (ST/RE-ISR), and major adverse cardiovascular events (MACEs). A total of 19 studies with 6256 participants were finally included in this meta-analysis. Results showed that the rates of TLR (P<0.00001), TVR (P<0.00001), CD (P=0.02), ST/RE-ISR (P<0.00001), and MACEs (P<0.00001) were significantly higher in the DES-ISR group than in the BMS-ISR group. No significant differences were found between the two groups in the rates of MI (P=0.05) and ACD (P=0.21). Conclusions. Our study demonstrated that patients with DES-ISR had worse clinical outcomes at the long-term follow-up than patients with BMS-ISR after the treatment of DES or DEB, suggesting that DES and DEB may be more effective for BMS-ISR than that for DES-ISR. Positive prevention of DES-ISR is indispensable and further studies concentrating on detecting the predictors of outcomes of DES-ISR are required.

Outcomes of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention With Drug-Eluting Stents Versus Bare Metal Stents for Acute Coronary Syndrome in Octogenarians

Angiology ◽  
2011 ◽  
Vol 62 (8) ◽  
pp. 620-624 ◽  
Author(s):  
Yuichiro Maekawa ◽  
Akio Kawamura ◽  
Shinsuke Yuasa ◽  
Yohei Ohno ◽  
Takahide Arai ◽  
...  
Keyword(s):  
Bare Metal Stents ◽  
Drug Eluting Stents ◽  
Metal Stents ◽  
Bare Metal ◽  
Long Term Outcomes ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Short And Long Term

The number of percutaneous coronary interventions (PCI) performed for octogenarians with acute coronary syndrome (ACS) continue to increase. The short- and long-term outcomes of intravascular ultrasound (IVUS)-guided PCI with drug-eluting stents (DES) or bare metal stents (BMS) for ACS in octogenarians, however, remain largely unknown. We analyzed clinical outcomes of octogenarians undergoing IVUS-guided PCI for ACS with either DES or BMS. During the study period, a total of 776 patients with ACS underwent IVUS-guided PCI and 75 of them were octogenarians. In-hospital mortality tended to be lower in the DES group than in the BMS group. Between 6 months and 1 year of follow up, treatment with DES compared with BMS tended to result in fewer target lesion revascularizations. Major adverse cardiac events were similar between patients receiving DES and BMS. In octogenarians with ACS treated with IVUS-guided PCI, DES appears as safe as BMS, providing similar short- and long-term outcomes.

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