scholarly journals ROLE OF HUMAN PAPILLOMAVIRUS IN CARCINOGENESIS OF DIGESTIVE TRACT

2021 ◽  
pp. 33-37
Author(s):  
G.V. Reva ◽  
V.E. Tolmachev ◽  
Yu.V. Dynda ◽  
A.R. Kim
Keyword(s):  
Human Papillomavirus ◽  
Digestive Tract

scholarly journals Pathogenic Role of Immune Evasion and Integration of Human Papillomavirus in Oropharyngeal Cancer

2021 ◽  
Vol 9 (5) ◽  
pp. 891
Author(s):  
Takashi Hatano ◽  
Daisuke Sano ◽  
Hideaki Takahashi ◽  
Nobuhiko Oridate
Keyword(s):  
Human Papillomavirus ◽  
Immune Evasion ◽  
Oropharyngeal Cancer ◽  
Current Knowledge ◽  
Immune Evasion Mechanism ◽  
Cell Cycle Activation ◽  
Genome Integration ◽  
Integration Mechanisms ◽  
E6 And E7

The incidence of oropharyngeal cancer (OPC) is increasing remarkably among all head and neck cancers, mainly due to its association with the human papillomavirus (HPV). Most HPVs are eliminated by the host’s immune system; however, because HPV has developed an effective immune evasion mechanism to complete its replication cycle, a small number of HPVs are not eliminated, leading to persistent infection. Moreover, during the oncogenic process, the extrachromosomal HPV genome often becomes integrated into the host genome. Integration involves the induction and high expression of E6 and E7, leading to cell cycle activation and increased genomic instability in the host. Therefore, integration is an important event in oncogenesis, although the associated mechanism remains unclear, especially in HPV-OPC. In this review, we summarize the current knowledge on HPV-mediated carcinogenesis, with special emphasis on immune evasion and integration mechanisms, which are crucial for oncogenesis.

scholarly journals Inconclusive role of human papillomavirus infection in breast cancer

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Yi Zhou ◽  
Jinyuan Li ◽  
Yuting Ji ◽  
Ming Ren ◽  
Bo Pang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Human Papillomavirus ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

scholarly journals The Role of Acquired Immunity in the Spread of Human Papillomavirus (HPV): Explorations with a Microsimulation Model

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0116618 ◽  
Author(s):  
Suzette M. Matthijsse ◽  
Joost van Rosmalen ◽  
Jan A. C. Hontelez ◽  
Roel Bakker ◽  
Inge M. C. M. de Kok ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Acquired Immunity ◽  
Microsimulation Model

Prognostic markers of high-grade squamous intraepithelial lesions: the role of p16INK4aand high-risk human papillomavirus

2007 ◽  
Vol 86 (1) ◽  
pp. 94-98 ◽  
Author(s):  
José Eleutério Jr ◽  
Paulo César Giraldo ◽  
Ana Katherine Gonçalves ◽  
Diane Isabelle Magno Cavalcante ◽  
Francisco Valdeci de Almeida Ferreira ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Prognostic Markers ◽  
High Grade ◽  
Squamous Intraepithelial Lesions ◽  
Intraepithelial Lesions

The role of human papillomavirus in carcinoma

1991 ◽  
Vol 25 (4) ◽  
pp. 698-705 ◽  
Author(s):  
Matthew Brett Quan ◽  
Ronald Leonard Moy
Keyword(s):  
Human Papillomavirus

The role of human papillomavirus vaccines in cervical cancer: Prevention and treatment

2018 ◽  
Vol 122 ◽  
pp. 92-97 ◽  
Author(s):  
Giorgio Bogani ◽  
Umberto Leone Roberti Maggiore ◽  
Mauro Signorelli ◽  
Fabio Martinelli ◽  
Antonino Ditto ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Cancer Prevention ◽  
Cervical Cancer Prevention ◽  
Papillomavirus Vaccines ◽  
Human Papillomavirus Vaccines ◽  
Prevention And Treatment

The role of human papillomavirus infection in prostate carcinoma

2010 ◽  
Vol 43 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Arezoo Aghakhani ◽  
Rasool Hamkar ◽  
Mahmoud Parvin ◽  
Nastaran Ghavami ◽  
Mahsa Nadri ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Prostate Carcinoma ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection
Sign in / Sign up

Export Citation Format

Share Document