scholarly journals Helicobacter pylori chronic gastritis: correlation between endoscopic findings and histopathology with special reference to updated sydney system

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Dr. Tarak Banik ◽  
◽  
Dr. Prasenjit Kumar Bar ◽  
Dr Saikat Mandal ◽  
◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Special Reference ◽  
Chronic Gastritis ◽  
Endoscopic Findings ◽  
Sydney System ◽  
Updated Sydney System

scholarly journals Evaluation of chronic gastritis with Helicobacter pylori using updated Sydney system

2021 ◽  
Vol 9 (9) ◽  
pp. 2728
Author(s):  
Anjana M. L. ◽  
Kavitha Yevoor
Keyword(s):  
Helicobacter Pylori ◽  
Chronic Gastritis ◽  
Histological Evaluation ◽  
Statistical Association ◽  
Histopathological Changes ◽  
Biopsy Specimens ◽  
Sydney System ◽  
Updated Sydney System ◽  
H Pylori ◽  
Significant Statistical Association

Background: Helicobacter pylori has been established as a major etiological factor in the pathogenesis of chronic gastritis. The aim of the study was to interpret the histopathological changes in chronic gastritis using updated Sydney system and the association with H. pylori infection.Methods: This was a 3 years study in which 62 gastric endoscopic mucosal biopsies taken from patients presenting with dyspepsia were included. Slides were stained with routine H and E and Giemsa for H. pylori detection in chronic gastritis cases. Grading of the variables were done with reference to Sydney system of classification.Results: Out of 62 gastric biopsy specimens, 55 cases (88.7%) were histopathological diagnosed as chronic gastritis. Among chronic gastritis, 21 (38%) cases showed H. pylori and majority of these being moderately (2+) positive. 27 (49%) cases showed neutrophilic activity with most of them showed mild (1+) activity. Chronic inflammation was seen 52 (94.5%) with majority of these graded as moderate (2+). Intestinal metaplasia was seen in 8 (14.5%) of cases with majority being mild (1+). Atrophy was seen only in 3 (5.4%) of cases with majority being mild (1+). Significant statistical association was found between H. pylori and neutrophilic activity (p<0.001).Conclusions: Histological evaluation of chronic gastritis using updated Sydney system of classification helps in detection of H. pylori infection and prevents further progression of the disease. 

scholarly journals Clinical Endoscopic and Histological Characteristics of Helicobacter Pylori Positive and Negative Armenian Children with Recurrent Abdominal Pain and/or Dyspepsia

2021 ◽  
Author(s):  
Tatevik Shahinyan ◽  
Gayane Amaryan ◽  
Artashes Tadevosyan ◽  
Christian Peter Braegger
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Clinical Symptoms ◽  
Recurrent Abdominal Pain ◽  
Infection Prevalence ◽  
Endoscopic Findings ◽  
Sydney System ◽  
Histological Characteristics ◽  
Updated Sydney System ◽  
Antral Biopsy

Abstract BackgroundRecurrent abdominal pain (RAP) and dyspepsia are common complaints in children. These symptoms are often associated with Helicobacter pylori (Hp)infection. Aim of the present study was to prospectively analyze clinical, endoscopic and histological characteristics of Hp+ and Hp- children with RAP and/or dyspepsia. MethodsPatients aged 2-18 years with RAP and/or dyspepsia, referred for upper endoscopy to Arabkir MC from November 2015 to December 2017, were involved in the study. Histology was assessed according to the updated Sydney system. Gastric and duodenal specimens were stained by modified Giemsa staining for Hp infection. One antral biopsy was cultured in Hp selective media. Results150 patients were included into the study: 70.7% Hp+,29.3% Hp-. Nausea and vomiting were significantly more common in Hp+ patients (p<0.05). Gastric nodularity (p=0.02), erosions in the stomach (p=0.056), and duodenal erosions (p=0.019) were more common in Hp+. Chronic active (p=0.027) and non-active gastritis (p=0.002), cumulative findings of metaplasia/dysplasia/atrophy in the stomach (p=0.014) and chronic non-active duodenitis (p=0.016), were significantly more common in Hp+ patients. ConclusionHp infection prevalence is high in Armenian children with dyspepsia and/or RAP. Clinical symptoms, endoscopic findings and histopathological findings were significantly different in Hp+ patients as compared to Hp- patients.

scholarly journals Helicobacter pylori infection and chronic gastritis; use of the Updated Sydney System in histopathological evaluation of gastritis

2019 ◽  
Author(s):  
Nushka Ubhayawardana ◽  
Manjula Weerasekera ◽  
Kamani Samarasinghe ◽  
Sameera Premalal ◽  
Deepaka Weerasekera ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Chronic Gastritis ◽  
Variable Number ◽  
Ulcer Disease ◽  
Chronic Active Gastritis ◽  
Sydney System ◽  
Histologic Lesion ◽  
Updated Sydney System ◽  
H Pylori

Abstract Objective Helicobacter pylori is a major cause for chronic gastritis and further it is associated with development of peptic ulcer disease and gastric cancer. Therefore, the objective of this study was to classify gastritis according to the updated Sydney system guidelines and find the association of H. pylori with each of graded variable. Number of 152 dyspeptic patients who underwent upper gastro-intestinal endoscopy at a Teaching Hospital were enrolled. Of the 2 biopsies collected one was used for PCR to detect H. pylori. The other biopsy was fixed in formalin followed by paraffin embedding and stained with H&E stain. Gastritis was classified microscopically according to the updated Sydney system. Results : Gastritis was reported over a wide age group ranging from 18-84 years with a mean age of 51 years. Based on histological findings, 12% of patients were diagnosed as H. pylori associated chronic active gastritis. There was no significant association between each graded variable and H. pylori positivity. Of the 152 dyspeptic patients 34 were positive by PCR for H. pylori infection. All the dyspeptic patients with H. pylori infection had chronic active gastritis, suggesting an etiologic role of the bacterium in the histologic lesion.

The Relationship Between Updated Sydney System Score and LDL Cholesterol Levels in Patients Infected with Helicobacter pylori

2008 ◽  
Vol 54 (3) ◽  
pp. 604-607 ◽  
Author(s):  
Metin Kucukazman ◽  
Bunyamin Yavuz ◽  
Muhammed Sacikara ◽  
Zeliha Asilturk ◽  
Naim Ata ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Ldl Cholesterol ◽  
Cholesterol Levels ◽  
Sydney System ◽  
Updated Sydney System ◽  
The Relationship

scholarly journals Chronic Gastritis Is Associated with a Decreased High-Density Lipid Level: Histological Features of Gastritis Based on the Updated Sydney System

2020 ◽  
Vol 9 (6) ◽  
pp. 1856 ◽  
Author(s):  
Dong-Hoon Kim ◽  
Byoung Kwan Son ◽  
Kyueng-Whan Min ◽  
Sang Kuk Han ◽  
Ji Ung Na ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Lipid Profile ◽  
Mononuclear Cell ◽  
Chronic Gastritis ◽  
Mononuclear Cells ◽  
Leukocyte Count ◽  
Low Density ◽  
Histological Features ◽  
Sydney System ◽  
Updated Sydney System

Chronic gastritis could activate a systemic inflammatory response that could result in adverse lipid profiles. To determine the severity of chronic gastritis, Helicobacter pylori (HP), mononuclear cell (lymphocytes and plasma cells), and neutrophil scores were assessed on the basis of the updated Sydney system (USS), which is widely used for histological grading. The aim of this study was to assess the relationships between gastric histological features and lipid profile levels. This study included 15,322 males and 5929 females who underwent a health checkup and gastric biopsy at the Kangbuk Samsung Medical Center (KBSMC). We analyzed whether the HP, mononuclear cell, and neutrophil grades according to the USS were related to serum leukocyte count, unhealthy behaviors, and lipid profile levels. Gastritis with HP, neutrophils, or moderate to severe mononuclear cells was associated with an elevated serum leukocyte count. A high leukocyte count was related to increased low-density lipoproteins (LDL) and triglycerides/very-low-density lipoprotein (VLDL) and decreased high-density lipoproteins (HDL). In multivariate analyses, chronic gastritis with HP or moderate to severe mononuclear cells was significantly associated with decreased HDL in males, while mononuclear cells were significantly related to decreased HDL in females. Chronic gastritis was associated with an increased systemic inflammatory response, which was associated with unfavorable lipid profiles, especially low HDL levels.

scholarly journals Association of Helicobacter pylori infection with nodular antritis and follicular gastritis

2006 ◽  
Vol 63 (3) ◽  
pp. 313-315 ◽  
Author(s):  
Ratko Tomasevic ◽  
Gradimir Golubovic ◽  
Miroslav Kiurski ◽  
Dragana Stankovic ◽  
Radoje Doder ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Case Report ◽  
Chronic Gastritis ◽  
Upper Gastrointestinal Endoscopy ◽  
Antral Mucosa ◽  
Urease Test ◽  
Sydney System ◽  
H Pylori ◽  
The Relationship ◽  
Upper Gastrointestinal

Introduction. Helicobacter pylori (H. pylori) infection is known to be the must common cause of chronic gastritis having some endoscopic and pathologic characteristies as determinated by the Sydney System for Gastritis Classification. The aim of our case report was to point out the relationship between an endoscopic finding of nodular antritis and the presence of H. pylori infection and active chronic gastritis. Case report. Our patient underwent upper gastrointestinal endoscopy for dyspeptic complaints and was diagnosed as having nodular antritis, but also underwent urease test and hystopathologic examination of antral mucosa, to determine the presence and density of H. pylori infection and the presence and severity of gastritis. After a course of anti H. pylori treatment, dyspepsia improved and new biopsy specimens obtained two months and six months afterwards revealed no pathological findings. Conclusion. The case report supported the association of H. pylori infection of lymphoid follicles with nodular gastric mucosis.

scholarly journals Distribución de estadios de OLGA y OLGIM según edad y estado del Helicobacter pylori en un hospital público nivel III en Lima, Perú

2021 ◽  
Vol 51 (1) ◽  
Author(s):  
Andrea Carlin Ronquillo ◽  
Alex Ventura León ◽  
Jorge L Espinoza Ríos ◽  
Eduar A Bravo Paredes ◽  
Paúl Gómez Hinojosa ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
High Risk ◽  
Upper Gastrointestinal Endoscopy ◽  
Gastric Intestinal Metaplasia ◽  
Endoscopic Control ◽  
Staging Systems ◽  
Sydney System ◽  
Group 5 ◽  
Updated Sydney System ◽  
H Pylori

Introduction. The operative link for gastritis assessment (OLGA) and the operative link on gastric intestinal metaplasia assessment (OLGIM) staging systems have been suggested to provide risk of assessment for gastric cancer. Objective. To evaluate the distribution of OLGA and OLGIM staging by age and Helicobacter pylori status. Material and methods. We studied 197 subjects undergoing elective upper gastrointestinal endoscopy. The presence of the H. pylori and histological changes were evaluated using the updated Sydney system. Stages III and IV of OLGA/OLGIM were considered high risk stages. Results. The H. pylori rate was 56.85% (112/197). High-risk OLGA/OLGIM cases were rare: 7/112 (6.5%) cases of OLGA in the H. pylori positive group and 6/85 (7%) in the H. pylori negative group; 5 (4.4%) cases of OLGIM in the H. pylori positive and 6 (7%) in the H. pylori negative. The proportion of advanced stages of OLGA and OLGIM increased with age (p < 0.001). High-risk OLGA was not found before age 40 regardless of the presence of H. pylori, but increased to 16.2%, 10.3%, 17.3% and 40.8% in subjects in the fourth, fifth, sixth and seventh decade of life respectively. The OLGIM high risk showed a similar trend: 0% before 40 years and up to 22.6% in people of 70 years. Conclusions. High-risk OLGA/OLGIM cases are infrequent before age 40 and increase significantly with age. No relation was found with the presence of the H. pylori. According to these protocols, only a fifth of the patients would strictly require endoscopic control.

Correlation Between Endoscopic and Histological Findings in Different Gastroduodenal Lesion and its Association with Helicobacter Pylori

1970 ◽  
Vol 2 (2) ◽  
pp. 6-10 ◽  
Author(s):  
A Sultana ◽  
SM Badruddoza ◽  
F Rahman
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Gastric Carcinoma ◽  
Chronic Gastritis ◽  
Normal Mucosa ◽  
Endoscopic Biopsy ◽  
Endoscopic Findings ◽  
Duodenal Lesions ◽  
H Pylori

This study had been planned to see the histomorphological pattern of gastric mucosal biopsy, demonstrate the organism H .Pylori and correlate with endoscopic findings. The study was carried out in the department of the Pathology Rajshahi Medical College, Rajshahi, Bangladesh, during the period from January 2006 to December 2007. Endoscopic biopsy specimens were obtained from 105 cases of gastro duodenal lesions. According to endoscopic findings out of 105 cases 69(65.7%) had gastric carcinoma, 06 (5.71%) had gastric ulcer, 05 (4.76%) had duodenal ulcer, 05 (476%) had gastritis and 20 (19.04%) had normal mucosa, reported as non-ulcer dyspepsia. Of the 69 endoscopically gastric carcinoma 59 (85.50%) were diagnosed histologically as adenocarcinoma and 10 (14.50%) were diagnosed histologically as chronic gastritis in which H.Pylori was positive in 27.5% and 14.50% positive in chronic gastritis. Of 06 gastric ulcer 03 (50%) was diagnosed histologically as gastritis and 03 (50%) were diagnosed histologically as gastric carcinoma. H. Pylori was positive in cent percent of gastritis. Of 05 duodenal ulcer 03 (60%) were diagnosed histologically as gastritis and 02 (40%) were diagnosed histologically as intestinal metaplasia H. Pylori was positive in 66.6% of duodenal ulcer. Of 05 gastritis were diagnosed histologically as gastritis 60% were postive for H.Pylori. Of 20 NUD 18 (90%) were diagnosed histologically as gastritis, 01 (05%) was diagnosed histologically as ulcer and 01 (05%) was diagnosed histologically as normal mucosa, all these cases no H. Pylori was found. Key Words: Helicobacter Pylori; Gastroduodenal Lesion; Association DOI: http://dx.doi.org/10.3329/akmmcj.v2i2.8164 AKMMC J 2011; 2(2): 06-10

Sign in / Sign up

Export Citation Format

Share Document