scholarly journals Microbial profile and risk factors of central venous catheter associated blood stream infections in Tertiary Care Hospital, Amritsar

2016 ◽  
Vol 4 (8) ◽  
pp. 1437-1442
Author(s):  
Dr. Loveena Oberoi ◽  
◽  
Dr. Pallavi Pallavi ◽  
Dr. Veena Chatrath ◽  
Dr. Pushpa Devi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Central Venous Catheter ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Venous Catheter ◽  
Blood Stream ◽  
Care Hospital ◽  
Central Venous ◽  
Blood Stream Infections ◽  
Microbial Profile

Central venous catheter—related blood stream infections: incidence, risk factors, outcome, and associated pathogens

2004 ◽  
Vol 18 (3) ◽  
pp. 304-308 ◽  
Author(s):  
Mandakini Pawar ◽  
Yatin Mehta ◽  
Pawan Kapoor ◽  
Jitendra Sharma ◽  
Abhinav Gupta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Central Venous Catheter ◽  
Venous Catheter ◽  
Blood Stream ◽  
Central Venous ◽  
Blood Stream Infections ◽  
Incidence Risk

Patient and central venous catheter related risk factors for blood stream infections in children receiving chemotherapy

2014 ◽  
Vol 62 (3) ◽  
pp. 471-476 ◽  
Author(s):  
Joanne Yacobovich ◽  
Tal Ben-Ami ◽  
Tameemi Abdalla ◽  
Hannah Tamary ◽  
Gal Goldstein ◽  
...  
Keyword(s):  
Risk Factors ◽  
Central Venous Catheter ◽  
Venous Catheter ◽  
Blood Stream ◽  
Central Venous ◽  
Blood Stream Infections ◽  
Related Risk

scholarly journals 183. Candidaemia in Children and Importance of Central Venous Catheter Removal

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S112-S113
Author(s):  
Kamile Arikan ◽  
Sevtap Arıkan-Akdaglı ◽  
Ates Kara
Keyword(s):  
Blood Culture ◽  
Central Venous Catheter ◽  
Blood Stream Infection ◽  
Tertiary Care ◽  
Venous Catheter ◽  
Blood Stream ◽  
Attributable Mortality ◽  
Care Hospital ◽  
Central Venous ◽  
Candida Spp

Abstract Background Candida is the most common cause of invasive fungal infection in healthcare settings and is associated with significant increases in healthcare resource utilization and attributable mortality. Methods This study was conducted in a pediatric tertiary care hospital from Turkey. We conducted a retrospective analysis in children ≤18 years with blood culture-proven candidaemia identified between December 2013 and November 2017. Sociodemographic variables,underlying condition, mortality, additional risk factors, origin of specimens were all recorded. Results A total of 236 episodes of candidaemia were identified over the study period. The median age of the patients was 600 days (4-6482). 106 specimens (44.9%) were cultured from patients under 1 year of age and 15 of 106 specimens were cultured from neonates. The most frequently isolated Candida spp. were C. albicans (42.%), followed by C. parapsilosis (30.5%), C. glabrata (7.6%), C. tropicalis (6.4%), C. krusei (2.5%), C. lusitaine (2.5%), C. dubliniensis (2.1%), C. kefir (0.8%), and C. pelliculosa (0.4%). In 11 of the 236 episodes (4.5%), two Candida spp were cultured at the same time.The most common coinfection was C. albicans and C. parapsilosis. 112 of the 236 episodes (47.5%) was due to central venous catheter-related blood stream infection. 47.5% of these patients were receiving total parenteral nutrition at the time of candidemia. Concomitant coagulase negatif staphylococcus bacteremia was present in 50 of 236 candidemia episodes (21.2%). Of 236 isolates, 74 (31.4%) was cultured from peripheral blood culture only, 95 (40.3%) from central venous catheter only, 67 (28.4%) from both peripheral and central catheter blood culture.Trombocytopenia was noted in 117 episodes (49.6%) and neutropenia in 45 episodes (19.1 Of the 112 central venous catheter-related candidemia, 35 (31.3%) resulted in death within 30 days from the onset of candidaemia (Figure 1). In 49 (45.%) episodes of central venous catheter-related candidemia, catheter was not removed and 40% of these episodes resulted as death.Catheter removal, thrombocytopenia, total parenteral nutrion were found to be associated with increased mortality in children under 1 year of age (P < 0.001). Conclusion Clinicians must be aware of candidemia in children due to high risk of mortality. Disclosures All authors: No reported disclosures.

scholarly journals A clinical study of patients with central venous catheter associated bloodstream infections in a tertiary care hospital

2020 ◽  
Vol 9 (11) ◽  
pp. 1665
Author(s):  
R. Abisha Rezia ◽  
R. Vijendra ◽  
Anjana Gopi
Keyword(s):  
Staphylococcus Aureus ◽  
Central Venous Catheter ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Bloodstream Infections ◽  
Venous Catheter ◽  
Care Hospital ◽  
Central Venous ◽  
Enterococcus Spp ◽  
Acinetobacter Spp

Background: Central venous access puts the patients at risk of iatrogenic complications and is associated with bloodstream infections. Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus and Methicillin Resistant Staphylococcus aureus (MRSA) are responsible for at least two-thirds of the infections followed by Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Enterococcus spp and Acinetobacter spp. Due to the scarcity of Central Venous Catheter associated Blood Stream Infections (CVC-BSI) data, this study was taken up in our tertiary care hospital. Aims: This study is aimed to study the profile of organisms causing CVC-BSI, assess their antimicrobial susceptibility, the clinical course and outcome.Methods: All subjects whose central venous catheter samples (n=84) were sent for culture and sensitivity during the study period were included in this prospective observational study. The study was done in the Department of Microbiology from July 2019 to December 2019. The catheter tips were streaked onto blood agar plate using Roll plate technique. After biochemical identification of the organisms, antimicrobial susceptibility testing was performed by modified Kirby-Bauer disc diffusion method as per the Clinical Laboratory Standard Institute (CLSI) guidelines. Results: Growth of pathogens was seen in 64.3% (n=54). The common organisms were Coagulase Negative Staphylococcus aureus (CONS) in 27.78% (n=15), Enterococcus spp, Klebsiella pneumoniae in 14.8% each (n=8) and Acinetobacter spp in 11.1% (n=6). Resistance was seen with amoxicillin + clavulanic acid, cefepime, ciprofloxacin and cefoperazone. The organisms were sensitive to levofloxacin, tetracycline and vancomycin.Conclusion: Aseptic precautions taken by the healthcare personnel will bring down the infections and curb the spread of multi-drug resistant hospital acquired infections.

scholarly journals Central Venous Catheter Tip Culture and Sensitivity Pattern from a Tertiary Care Hospital in Jammu Region, India

2019 ◽  
Vol 7 (4) ◽  
pp. 101-106
Author(s):  
P. Sharma Perika ◽  
S. Sudan N. Rajput ◽  
S. Gupta Y. Bhandari ◽  
R. Tomar
Keyword(s):  
Central Venous Catheter ◽  
Venous Catheter ◽  
Blood Stream ◽  
Care Hospital ◽  
Central Venous ◽  
Gram Positive ◽  
Blood Stream Infections ◽  
Gram Negative ◽  
Catheter Tip ◽  
Gram Positive Cocci

The use of Central Venous Catheters (CVC) in critically ill patients often leads to Catheter Related Blood Stream Infections (CRBSI). Blood stream infections which are associated with catheter is associated with high morbidity and mortality. Aim of the study is to find the type of organisms isolated from Central venous catheter tip and to determine their antimicrobial susceptibility pattern. A total of 100 samples were received in our laboratory over a period of one year. Samples were processed; organisms were isolated and subjected to antimicrobial sensitivity according to standard laboratory procedures. AST interpretation was done according to latest CLSI Guidelines. Of the 100 samples received in our laboratory, 11(11%) showed no growth or insignificant growth. 64% of the total samples were Gram Negative Bacilli and 23% were Gram Positive Cocci, 2% were Candida albicans. Escherichia coli and Staphylococcus aureus were the most common organisms isolated among gram negative bacilli and gram positive cocci respectively. Sensitive drugs in case of gram positive cocci were vancomycin and linezolid and in case of gram negative bacilli were Colistin and polymyxin B.

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