scholarly journals The effect of two different doses of dexmedetomidine to attenuate cardiovascular and airway responses to tracheal extubation: a double blind randomized controlled trial

2016 ◽  
Vol 4 (8) ◽  
pp. 1392-1403
Author(s):  
Dr Deepu Antony ◽  
◽  
Dr Davies C V ◽  
Dr Mariam Koshi Thomas ◽  
Dr Usha Shenoy ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Tracheal Extubation ◽  
Double Blind ◽  
Randomized Controlled ◽  
Airway Responses ◽  
Different Doses

scholarly journals Mivacurium Compared with Three Different Doses of Suxamethonium for Nasotracheal Intubation

1998 ◽  
Vol 26 (5) ◽  
pp. 521-525 ◽  
Author(s):  
R. Hodgson ◽  
P. Harvey ◽  
R. Burrows
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Nasotracheal Intubation ◽  
Maxillofacial Surgery ◽  
Double Blind ◽  
Randomized Controlled ◽  
Intubating Conditions ◽  
Significant Difference ◽  
Rectal Indomethacin ◽  
Different Doses

Suxamethonium in the doses of 1.0, 0.5 and 0.25 mg/kg was compared with mivacurium 0.15 mg/kg in 80 patients requiring nasotracheal intubation for maxillofacial surgery in a double-blind randomized controlled trial. Anaesthesia was induced with thiopentone 5 mg/kg and alfentanil 15 μg/kg. Patients were randomly allocated to one of the four relaxant groups. Anaesthesia was maintained with enflurane in 70% nitrous oxide and 30% oxygen and analgesia provided with intravenous pethidine 0.5 to 1.5 mg/kg and rectal indomethacin 100mg. All patients given mivacurium or suxamethonium 1mg/kg had acceptable intubating conditions. Significantly fewer patients given suxamethonium 0.5 mg or 0.25 mg/kg had acceptable intubating conditions (90% and 70% respectively) (P=0.003). Poor intubating conditions requiring additional relaxation were seen in two patients given suxamethonium 0.25 mg/kg and two given 0.5 mg/kg, while no patients given suxamethonium 1.0 mg/kg or mivacurium 0.15 mg/kg required additional relaxation (P=0.004). Only four patients had postoperative myalgia, all of whom were given suxamethonium 0.5 mg/kg or more but no significant difference between groups could be demonstrated.

Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial

2001 ◽  
Vol 26 (1) ◽  
pp. 67-71 ◽  
Author(s):  
S. A. Ahmadi-Abhari ◽  
S. Akhondzadeh ◽  
S. M. Assadi ◽  
O. L. Shabestari ◽  
Z. M. Farzanehgan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Side Effects ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled
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