Changes in Inflammatory and Vasoactive Mediator Profiles During Valvular Surgery With or Without Infective Endocarditis: A Case Control Pilot Study v1 (protocols.io.9esh3ee)

protocols.io ◽  
2019 ◽  
Author(s):  
Mahmoud Diab
Keyword(s):  
Infective Endocarditis ◽  
Pilot Study ◽  
Case Control ◽  
Valvular Surgery ◽  
Vasoactive Mediator

scholarly journals Changes in inflammatory and vasoactive mediator profiles during valvular surgery with or without infective endocarditis: A case control pilot study

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0228286 ◽  
Author(s):  
Mahmoud Diab ◽  
Raphael Tasar ◽  
Christoph Sponholz ◽  
Thomas Lehmann ◽  
Mathias W. Pletz ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Pilot Study ◽  
Case Control ◽  
Valvular Surgery ◽  
Vasoactive Mediator

scholarly journals 705. Factors Associated with Local Invasion in Infective Endocarditis: a Nested Case-control Study

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S403-S403
Author(s):  
Abarna Ramanathan ◽  
James Witten ◽  
Steven M Gordon ◽  
Brian Griffin ◽  
Gosta Pettersson ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Aortic Valve ◽  
Case Control Study ◽  
Cleveland Clinic ◽  
Case Control ◽  
Paravalvular Leak ◽  
Multivariable Logistic Regression Model ◽  
Local Invasion ◽  
Nested Case Control ◽  
Control Study

Abstract Background A substantial proportion of infective endocarditis (IE) cases are complicated by local invasion. The purpose of this study was to identify patient and disease characteristics that increase the odds of local invasion in surgically treated IE patients. Methods This was a nested case-control study. All episodes of IE for patients admitted to Cleveland Clinic from January 1st, 2013 – June 30th, 2016 were identified from the Cleveland Clinic IE Registry. Patients >18 years of age who underwent surgery for IE were included. Data was compiled by manual review of the Electronic Medical Record. Local invasion, defined as peri-annular extension, peri-valvular abscess, intra-cardiac fistula or pseudoaneurysm, was ascertained from the surgical operative note. Associations of selected factors with local invasion were examined in a multivariable logistic regression model. Results Among 510 patients who met inclusion criteria, 206 had local invasion. Mean age was 56 years and 369 (72 %) were male. Overall 344 (67 %) had aortic valve, 228 (45%) mitral valve, and 66 (13%) tricuspid or pulmonic valve involvement. Aortic valve involvement (OR 5.76, 95% CI 3.44 – 9.98), mechanical valve (OR 7.63, 95% CI 3.63 – 17.07), bioprosthetic valve (OR 3.20, 95% CI 1.99 – 5.19), significant paravalvular leak (OR 2.27, 95% CI 1.09 – 4.97), new atrioventricular nodal block (OR 3.05, 95% CI 1.57 – 6.09), Staphylococcus aureus infection (OR 2.11, 95% CI 1.20 – 3.76), coagulase negative staphylococcal infection (OR 2.38, 95% CI1.27 – 4.54), and non- viridans group streptococcal infection (OR 4.21, 95% CI 1.81 – 10.06) were significantly associated with local invasion. Conclusion Intra-cardiac and microorganism factors, but not comorbid conditions, are associated with local invasion in IE. Disclosures All Authors: No reported disclosures

Geriatric Inclusive Art and Length of Stay in Acute Care Unit: A Case-Control Pilot Study

2012 ◽  
Vol 60 (8) ◽  
pp. 1585-1587 ◽  
Author(s):  
Olivier Beauchet ◽  
Samantha Remondière ◽  
Micheline Mahé ◽  
Florence Repussard ◽  
Frederic Decavel ◽  
...  
Keyword(s):  
Pilot Study ◽  
Length Of Stay ◽  
Acute Care ◽  
Case Control ◽  
Acute Care Unit

scholarly journals Case-Control Pilot Study of Soft Contact Lens Wearers With Corneal Infiltrative Events and Healthy Controls

2016 ◽  
Vol 57 (1) ◽  
pp. 47 ◽  
Author(s):  
Kathryn Richdale ◽  
Dawn Y. Lam ◽  
Heidi Wagner ◽  
Aaron B. Zimmerman ◽  
Beth T. Kinoshita ◽  
...  
Keyword(s):  
Pilot Study ◽  
Contact Lens ◽  
Case Control ◽  
Healthy Controls ◽  
Soft Contact ◽  
Soft Contact Lens

scholarly journals HACEK infective endocarditis: Epidemiology, clinical features, and outcome: A case–control study

2018 ◽  
Vol 76 ◽  
pp. 120-125 ◽  
Author(s):  
Juan Ambrosioni ◽  
Clara Martinez-Garcia ◽  
Jaume Llopis ◽  
Cristina Garcia-de-la-Maria ◽  
Marta Hernández-Meneses ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Clinical Features ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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